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Simple and chic, artisan jewelry designer Judy Morgan's "Micro Life Necklace" is handcrafted of oxidized sterling silver and 18k yellow gold. 2" x 3/4" wide. Hangs from a 20-inch adjustable blackened sterling silver chain.
A massage's quality depends on the giver and receiver of the massage. That's why it's important that you have the right information. The piece that follows will provide you with helpful massage tips. After getting a massage, drink plenty of water. As you receive a massage, there are toxins being released from muscles into your body. Negative side effects can be minimized and toxins flushed out by drinking water. Drink about 2 to 3 the first hour, and drink at least eight more in the next twenty-three hours. Speak with a massage therapist and/or purchase a book that provides you with information about trigger points if you find that your muscles ache continuously. Trigger points, or tiny knots, often reside in tight muscles. Trigger points send pain to different locations in your body, which is why a back injury can cause pain in your buttocks and legs. You can learn how to treat these painful points by visiting a massage therapist or reading books. An open mind is key to a great massage. The process is not always something that you may know about. You should not allow this to keep you from enjoying the experience. Try to just let yourself relax and enjoy the massage that you are receiving. TIP! You should always make use of your thumbs when giving a massage. Your thumbs are a strong part of your hand so you can use them to stimulate the muscles. Do not eat before a massage. If you feel bloated after a meal, lying down can feel very uncomfortable. Wait until you have digested your dinner. This can aid in getting a full treatment by letting you assume various positions. Have a massage done twice a week. Oftentimes, massages on a regular basis helps a person's overall mental and physical health. Massages also relax you and help reduce stress. Although it may not be possible for you, see if you can swing two massages a week. If you are among the many people who deal with arthritis, then you are aware of the amount of pain involved. Medicine can help, but it does not relieve all the pain. Therefore, you should consider getting yourself a massage to treat this condition. A good massage can help improve blood flow and enhance circulation, thus reducing overall pain and discomfort. Massages are therapeutic, whether you're the giver or the receiver. If you'd like to make sure you are having a great massage, use all the tips laid out here. Current techniques are important so stay up-to-date.
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Generally, all the Deidre Knight books are listed in alphabetical order. If you want to buy, just click the format you like and you'll be taken straight away to an online bookstore that sells the Deidre Knight book you're looking at. If you click the book title you'll stay on this site and visit a page here for more information about the particular Deidre Knight book you've selected. I don't add things to your cart at any bookstore so you can also just use the format links to find out more information. Bookstore links do open in a new window though! Enjoy browsing all the Deidre Knight books on the site! Click one of the links below to be taken directly to the search results for Deidre Knight at any of these online book stores. Deidre Knight books in print, ebooks and audio books at Amazon.com. Deidre Knight ebooks for download at ebooks.com. Deidre Knight books in print, ebooks and audio books at Amazon.co.uk. Deidre Knight books in print, ebooks and audio books at Amazon.
Previous work, by us and others, has shown that mammalian galectins-1 have a growth-inhibitory activity for mammalian cells which is apparently independent of their -galactoside binding site. We have made recombinant human galectin-1 as a bacterial fusion protein with an N-terminal hexahistidine tag. This protein displays both haemagglutination and growth-inhibitory activities, even in the presence of the hexahistidine tag. Site-directed mutagenesis of this protein has confirmed the independent nature of the protein sites responsible for the two biological activities. Mutant proteins were created, which displayed each activity in the absence of the other. Human galectin-1 possesses a growth-inhibitory site, which is not part of the -galactoside binding site. A surface loop, comprising amino acid residues 2530, and joining two internal -strands, forms part of the growth-inhibitory site. This region is relatively close to the N-terminus of the protein, and N-terminal substitutions or extensions also affect growth-inhibitory activity. Further experiments will be necessary to fully define this site. It is now widely accepted that several galectins, and galectin-1 in particular, have biological functions over and above their obvious role in the binding or cross-linking of -galactoside-containing glycans [13]. The concept of a galactose-binding protein as a negative growth regulator was first seriously proposed when a protein from mouse fibroblast cultures, the murine homologue of galectin-1, was shown to have both properties . These workers went on to demonstrate that growth-inhibitory activity of this mGBP was present even when it bound a glycan at its galactose-binding site , suggesting that the two properties were independent functions of galectin-1. In fact, evidence for a growth-inhibitory phase could be seen in several earlier reports of the mitogenic activity of galectins from other species [68]. There was some evidence for a similar activity associated with human galectin-1, and it was suggested that proteolysis of secreted galectin-1 could account in part for the action of a growth-related cell-surface proteinase . In an attempt to test this hypothesis, recombinant human galectin-1 was prepared as a bacterial fusion protein with glutathione-S-transferase . Both the fusion protein, and the galectin-1 derived from it by proteolysis and re-purification, functioned as multivalent lectins, and displayed mitogenic activity, which was inhibited by lactose. Growth-inhibitory activity was not a property of the intact GST-galectin fusion protein, but only of the cleaved and purified galectin-1, and lactose did not inhibit this activity. It seemed likely that the GST domain of the fusion protein may sterically restrict access to a growth-inhibitory site on the galectin domain, but it clearly did not have a similar steric effect upon the galactose-binding site. These observations strengthened the case for independent galactose-binding and growth-inhibitory sites on the galectin-1 molecule. Specific mutagenesis of the recombinant galectin molecule is an obvious way of confirming this conclusion. Consideration of both tertiary structure and mutagenesis studies suggests that histidine-45, asparagine-47, arginine-49, tryptophan-69, glutamate-72 and arginine-74 are all involved in, or influence, sugar binding [1114]. (In numbering galectin-1 amino acid residues, we have found it more convenient to number from the N-terminal methionine, rather than to use the convention of Abbott and Feizi , who numbered from alanine-2, which is the N-terminus of the mature, natural protein). It should thus be straightforward to make a substitution mutant of galectin-1, in which galactose-binding activity is greatly reduced, or totally ablated. The assay of growth-inhibitory activity in such a mutant should indicate the existence, or otherwise, of a separate growth-inhibitory site. The earlier mutagenesis studies also suggest, however, that the yield and/or solubility of bacterial mutant galectins may often be low [11, 14]. Our own experience was of poor solubility and yield for mutated or truncated GST-galectin fusion proteins (A. Cameron, K.Y. Chung and KS, unpublished observations). In attempting this study, we therefore thought it worthwhile to adopt another expression vector. The ProEX system produces fusion proteins with a short N-terminal extension, containing a hexahistidine sequence for nickel ion chelation chromatography . This was chosen to produce recombinant proteins that were not dependent on -galactoside binding for their purification, and were at the same time smaller, to minimise problems due to poor solubility and to steric interference between domains. It may also be possible to identify a growth-inhibitory site directly by site-specific mutagenesis. The steric interference with growth-inhibitory activity, exerted by the GST domain attached to the N-terminus of galectin-1 in the fusion protein, does offer some insight into the possible location of such a site. Consideration of the three-dimensional structure of galectin-1 [12, 13], in conjunction with that observation, suggested additional sites for mutagenesis. The structure bears a strong resemblance to that of galectin-2 . Each monomer has a -sandwich structure, comprising two antiparallel -sheets of six (S1S6) and five (F1F5) strands, respectively. The -strands are joined by turns or relatively short loops; almost 70% of the amino acids are in -strands. The galactose-binding site is comprised of residues in the S4, S5, S6 and F3 strands. The N- and C-termini of the monomer are located close together, on the opposite side of the structure from the galactose-binding site. The surface that incorporates both termini is the contact region in the self-association of two monomers. Whilst it seems unlikely that the growth-inhibitory site could be directly on this "dimerisation interface", it may be close to it, as deduced from the steric effects of N-terminal extension. We identified the surface loops of the structure, located close to this interface, and distant from the galactose-binding site, and chose convenient amino acids within them for mutagenesis. Using this rationale, we have created mutant proteins, which displayed either galactoside-binding or growth-inhibitory activites in the virtual absence of the other. A surface loop, comprising amino acid residues 2530, and joining two internal -strands, forms part of the growth-inhibitory site. This region is relatively close to the N-terminus of the protein, and N-terminal substitutions or extensions also affect growth-inhibitory activity. Figure 1 summarises SDS-PAGE analysis of several of the galectin-1 preparations. The hexahis-galectin-1 fusion protein corresponds to a protein band at about 16 kDa, and most preparations contain traces of a dimer at about 32 kDa, as was previously observed with GST-galectin-1 . Despite the altered expression system, many mutant fusion proteins were still produced in low yields. In most cases where the yield of a mutant was low, there was a strong protein band at 16 kDa in the bacterial pellet, probably indicating protein precipitation following expression (not shown). As noted below, several of the mutants tended to precipitate slowly at the higher concentrations used for testing cell growth inhibition, and we also noted that some of these proteins precipitated even from much more dilute solutions after prolonged storage at -20C. Table 1 summarises our findings with each of the mutants of galectin-1. Two of the mutant proteins (R49G and D47N) were produced in such low yields that complete experimental investigation was not feasible, but the partial findings were of some interest. In addition to these positive cases, we also created cDNAs corresponding to the mutants V6D and A28D, but in neither case could we detect expressed protein in E. coli DH5. Yields and Biological Activities of Recombinant Galectin-1 Derivatives For each mutation in galectin-1, the yield of protein per litre of bacterial culture, the endpoint of the haemagglutination titration (in g/ml) and the concentration giving 50% inhibition of fibroblast growth (I50, in g/ml) are listed. The three entries marked * are for low-yield mutations, for which full analysis was not feasible. The final row contains data for the M1R mutant following thrombin cleavage and repurification. One hope was that, with a relatively small fusion peptide tag, the recombinant hexahis-galectin-1 (wild-type) would display full biological activities without the need for proteolytic cleavage and protein re-purification. This was indeed the case. The endpoint of the haemagglutination titration was 1 g/ml for the hexahis-galectin-1, compared to 1.3 g/ml for the GST-galectin 1 fusion protein. It should also be noted that the growth-inhibitory activity seen here (I50 = 5 g/ml) was about 1215 times greater than with the recombinant galectin-1 cleaved from a GST-galectin 1 fusion protein by thrombin , and roughly comparable with that of natural human galectin-1 . It is still, however, about tenfold less active than recombinant mouse or human galectin expressed in COS-1 cells [4, 22]. The different growth-inhibitory activities of our two recombinant galectins-1 may indicate that the chemical nature of the N-terminal extensions may have a greater effect on this activity than their size, though a very large extension, such as the entire GST molecule, was clearly inhibitory. Although the linker peptide of hexahis-galectin-1 contains a renin-sensitive site for proteolysis, renin action was not tested experimentally, as it would still leave an N-terminal tripeptide extension. Arginine-49 is located in the S4 -strand, in the scheme of Lobsanov et al. To our knowledge, it has not been modified in galectin-1 before now, but it has been shown to be located at the galactose-binding site, interacting with the 4-hydroxyl of the galactose residue, in the three-dimensional structures proposed by Bourne et al. and Liao et al. We thus expected that the R49G mutant galectin-1 would show reduced, or at least altered lectin activity, but in fact it was not significantly different from that of the control recombinant galectin-1. Because the yield of soluble protein was low, no further work was done with this mutant. A D47N mutation, also in the S4 -strand, has been previously reported as lectin-negative . We were able to confirm this finding, but, again, the yield of soluble protein was too low to carry out further experiments. In the cases of two mutant proteins with reduced haemagglutination activity, additional experiments were done, to distinguish between a failure to bind to erythrocyte surface -galactoside binding sites, and a reduction in erythrocyte cross-linking, either of which would result in reduced haemagglutination. Pretreatment with saturating concentrations of the mutant galectin-1 was followed by a haemagglutination titration with wild-type galectin-1. For both the P79R and the C131S mutants, this procedure resulted in agglutination at approximately the same endpoint (1 g/ml) as with wild-type galectin-1 in a control experiment. If the mutant galectin-1 was binding to the erythrocyte surface, but failing to cross-link erythrocytes, we would have expected to see reduced haemagglutination with the wild-type galectin, as the mutant would block binding sites. Thus, in each case, the mutations disrupt the -galactoside binding site, rather than the dimerisation of the galectin-1. This finding was confirmed by failure of the mutant protein in lectin-affinity chromatography (not shown). The dimeric nature of several of the mutant galectins-1, including P79R, is also shown by gel filtration (Figure 2). Lysozyme (14.5kDa) was used as a standard, which would co-elute with the galectin-1 monomer, but it is clear that all of the galectin preparations are substantially bigger under non-denaturing conditions. Gel Filtration of Recombinant Galectin-1 and Variants. Galectin-1 preparations purified by metal chelation chromatography were subjected to gel filtration on a Sephadex G-50 gel filtration column (60 1 cm; equilibrated in 30 mM Tris-HCl buffer pH 7.5). Fractions of 2 ml were collected, and absorbances at 280 nm measured. Normal galectin-1 ▪️ N46 D mutant P79R mutant Bacterial lysozyme. The P79R mutation occurs in a conserved, surface loop, between the S6 and F3 -strands. It is relatively distant from the galactose-binding site, but is closer to the dimerisation interface of galectin-1 [12, 13]. It was thus somewhat surprising that this mutant protein had a greatly reduced haemagglutinin activity, over two orders of magnitude below the control. This reduction was due to a loss of affinity for glycans, rather than to loss of cross-linking ability. Equally surprising was the observation that P79R retained full antiproliferative activity. Even if the substitution affects glycan binding as a consequence of a generally disruptive effect on tertiary structure, the retention of growth-inhibitory activity is significant. This is a clear confirmation that the galactose-binding and growth-inhibitory sites of galectin-1 are largely or wholly independent. It may be noteworthy that the elimination of the galactose-binding activity does not seem to result in more productive binding at the growth-inhibitory site. The C131S mutation is also located close to the dimerisation interface, but in a surface -strand (F1), rather than a loop. This galectin-1 variant was produced in low yield, and was totally devoid of haemagglutinin activity, but retained most of the growth-inhibitory potential of the wild-type. The loss of haemagglutinin activity is apparently caused by disruption of the -galactoside-binding site. An earlier analysis of a C131S substitution confirmed the low yield of protein, but reported a relatively normal lactose binding value . Substitutions in the extreme N-terminal region have been reported to disrupt hamster galectin-1 dimerisation, but concomitant substitutions in the C-terminus (F127, I129 and V132) led to a loss of lactose-binding affinity . Cysteine-131 can potentially form a disulphide bond with C2, but failure to make this, and other disulphide bonds (C17 C89 and C43 C61), favours lectin activity . A human galectin-1 variant with all six cysteines replaced by serines retains haemagglutinating activity . It has been shown that the oxidative loss of lectin activity correlates with the formation of disulphide bonds , and two more recent reports suggest that some biological activities are associated only with this structural form [24, 26]. In the present case, the ability to demonstrate lectin and growth-inhibitory activity with identical galectin-1 samples argues against the proposal that the growth-inhibitory activity is a property only of the oxidized, disulphide-bonded form. The D103A mutation is located in a surface loop, connecting adjacent antiparallel -strands (F4F5), but is distant from both the dimerisation interface and the galactose-binding site. This substitution did not appear to affect the lectin function of galectin-1 (Table 1), though growth-inhibitory activity was somewhat reduced, and the titration of this activity was obscured by precipitation at higher concentrations. This latter finding was somewhat surprising, in view of the very high yield of this protein (8 mg/l) in the bacterial expression system. Following our failure to detect expression of an A28D mutant (in another surface loop, F2S3), we were able to express an A28R mutant, though the A28R protein was in low yield, and impure following Ni-NDA affinity chromatography, and we were unable to further purify it by Sephadex gel filtration or galactosyl-agarose affinity chromatography (not shown). An unknown protein of about 25 kDa was a persistent contaminant. The data reported in Table 1 was obtained with a protein sample containing 5060% of the galectin-1 component, as estimated from the SDS-PAGE result. Again, the mutation affected galactose binding, but, in this case, growth-inhibitory activity was also greatly reduced. Despite the reservations imposed by the low yield and impurity of the sample, this observation offered a clue to the possible localization of the growth-inhibitory site, and we decided to make further mutational substitutions in this region of galectin-1. The K29M mutation, also in the F2S3 loop, resulted in a galectin that retained its galactose-binding activity. Testing of growth-inhibitory activity was initially obscured by the precipitation of this protein at high concentrations (above 100 g/ml), but it became clear that it had totally lost its ability to inhibit fibroblast growth. Whilst this radical substitution, of a moderately hydrophobic amino acid for a charged residue, clearly had an effect upon the solubility of the protein, (though, again, not on protein expression) the complete retention of lectin activity argued for the maintenance of overall three-dimensional structure. The K29T mutant, with a less radical substitution, was also a normal lectin, but equally devoid of growth-inhibitory activity (see Table 1). As a further check upon the importance of this part of the galectin-1 molecule to its growth-inhibitory activity, a D27N mutant was made and tested, and demonstrated full lectin activity, but significantly reduced growth-inhibitory activity (Table 1). If the D27 K29 region of galectin-1 is part of a growth-inhibitory site, then the effect of N-terminal modifications on growth-inhibitory activity may be explicable, as the "natural" amino terminus is within 810 Angstroms of these amino acids . It seems possible that the reduction of this activity, seen in both of our recombinant galectin types, hexahis- and GST-derived, may be due to modification of the N-terminus. As already discussed, it cannot simply be a steric restriction by the extended N-termini, as this would have a more marked effect on hexahis-galectin-1, whereas the reverse is true. To further investigate this region, we designed a forward PCR primer intended to substitute methionine-1 with an arginine (M1R). The M1R fusion protein was expressed in high yield, and was fully functional as a haemagglutinin, but was devoid of growth-inhibitory activity (Table 1). Rather than allowing it to substitute for the terminal amino group, the positioning of the positively-charged arginyl side-chain acts to inhibit the action of the growth-inhibitory site, which helps confirm that the N-terminal region of the normal protein is close to, or part of this site. It also seemed possible that thrombin might remove the N-terminal 14-residue peptide (hexahis-linker-arginine) from the M1R recombinant protein, and thus re-create the natural, methionine N-terminus. Thrombin treatment and repurification of the protein resulted in a fraction that did not bind to the Ni-NDA-agarose affinity column, so had lost the N-terminal hexahis region. It retained haemagglutinin activity, and had also recovered growth-inhibitory activity, though was not as effective as the wild-type galectin-1. It is possible that this reduction in growth-inhibitory activity (I50 = 24 cf 5 for wild-type galectin-1) reflects the effect of other thrombin cleavages within the molecule, as was seen previously with the GST-derived galectin-1 . In this case, N-terminal amino acid sequencing, following removal of the GST with thrombin revealed a minor component corresponding to the sequence beginning at F50. We deduced that this could be due to a thrombin cleavage at R49-F50. This protein was indistinguishable from intact recombinant galectin-1 in SDS-PAGE. In the present case, we have not examined this experimentally. Figure 3, derived from a structural model , shows the part of the protein (shaded region c) that has been demonstrated to have a role in the growth-inhibitory activity. The -galactoside-binding site (region a), and the dimerisation interface (region b) are also indicated. The elements of the growth-inhibitory site that have so far been identified would all be contained within a truncated galectin-1, containing the first 35 residues (the S1, F2 and S3 -strands, and connecting loops), in addition to the fusion tag. Although we were able to amplify this part of the galectin-1 cDNA, and clone it into the ProEx vector, we were unable to detect any expression in E. coli (not shown). Fusion proteins with an N-terminal tag have given valuable clues to the nature of the growth-inhibitory site, but, for further elucidation of the involvement of the N-terminus, it would be better in the future to use C-terminally-tagged proteins, or to express galectin-1 without any tag, and to use glycan-agarose affinity chromatography for purification of the recombinant proteins. The extreme C-terminus is also part of the dimerisation interface, but points in the opposite direction to the N-terminus (see Figure 3), so C-terminal extensions may not affect the growth-inhibitory site, though, as already noted, C-terminal substitutions may inhibit -galactoside binding . Location of Active Sites within the Galectin-1 Structure This figure is adapted from one designed to show the three-dimensional structure of galectin-1 (Bourne et al., 1994). The three shaded boxes indicate regions involved in glycan binding (a), dimerisation (b), and cellular growth inhibition (c). The D27 K29 region forms part of a DAKSF sequence (residues 2731) that is totally conserved in the mammalian galectins-1 , but is totally different from the corresponding residues in other galectins , for which growth-inhibitory properties have not been reported. However, there is no strong argument here for the evolutionary conservation of a functional part of the galectin-1 structure. Most of the sequences of the mammalian galectins-1 are strongly conserved throughout, whereas, when we consider the whole galectin family, the interstrand loops, and even the -strands not involved in galactose binding, are not strongly conserved. In summary, we have shown that we can ablate the -galactoside binding activity of human galectin-1 by mutation, with no effect on the cellular growth-inhibitory activity, confirming that these are two independent functions of the protein. By further mutational studies, we have at least partially defined the amino acids that make up the growth-inhibitory site in galectin-1. A surface loop, comprising amino acid residues 2530, and joining two internal -strands, contains amino acids which contribute to the growth-inhibitory site. This region is relatively close to the N-terminus of the protein, and N-terminal substitutions or extensions also affect growth-inhibitory activity. Further mutational studies may be necessary to fully define the growth-inhibitory site. The ProEX expression system offers some advantages in the production of bacterial recombinant galectin-1. Our original interest in galectin-1 was as a putative substrate for a growth-regulatory, cell-surface proteinase . Inhibition of the proteinase led to an accumulation of endogenous galectin-1 in the culture medium. The inhibitory action of this galectin-1 could, at least in part, account for the growth-inhibitory effect observed when the proteinase was inhibited. The fact that the recombinant hexahis-galectin-1 has a similar growth-inhibitory activity to the natural protein means that it can be used more realistically in future experiments in this area. Some of these mutants may enable us to assess the significance of each galectin-1 function to tumour growth and metastasis. We have shown that HEp-2 tumour cells do not express galectin-1, but respond to exogenous galectin-1 as a growth inhibitor . Transfection of HEp-2 cells with each galectin-1 gene variant will permit the study of effects on growth and metastasis, both in vitro, and then in vivo. The galectin-1 variant, P79R, which retains growth-inhibitory activity and reasonable solubility, but has little lectin activity, may be the starting-point for the creation of an effective antitumour agent. It would not have the mitogenic activity seen with native galectin-1 , nor would it be involved in non-productive binding to galactosides in the extracellular matrix. This galectin-1 variant could also be used to identify the cellular receptor responsible for the growth-inhibitory effect, since binding to cellular glycans will be minimised. Unless otherwise noted, molecular biology reagents were purchased from Gibco-BRL and all other reagents were from Sigma. The plasmid expression vector ProEX was purchased as part of a kit, which also included the corresponding nickel-containing affinity matrix. We used standard protocols for techniques such as DNA restriction and ligation, bacterial transformation, and agarose gel electrophoresis . Galectin-1 cDNA was re-amplified from human fibroblast cDNA, using the GRP3 and GRP4 primers, as previously described . Specific mutations were introduced using the Overlap Extension PCR technique , which uses complementary forward and reverse oligonucleotide primers incorporating the intended substitution. Primers were used as specified in Table 1, in conjunction with the GRP3 and 4 primers. For mutations close to either end of the galectin-1 gene, extended and modified versions of GRP 3 or 4 were used. MasterMix (Qiagen; 25 l) was used as a source of buffer, nucleotides and polymerase for the PCR reaction, together with 20 pmol of each primer and 2 g template DNA in a final volume of 50 l, containing 1 mM Mg Cl2. Thirty cycles of PCR were performed, with 30 s at 95C for denaturation, 90 s at 55C for annealing, and 60 s at 72C for polymerase extension. In some cases, the 55C annealing temperature was inappropriate for particular overlapping primers, and was modified to suit the primer composition, usually to 4547C. The amplified product was run on a 1.0% agarose horizontal gel in 40 mM Tris-acetate, pH 8.0, containing 1 mM EDTA buffer, cut out of the gel and purified using the Rapid Extraction protocol (Gibco-BRL). The product was restricted with Bam H I and Sal I restriction enzymes and ligated using T4 DNA ligase into the ProEX HTb vector restricted with the same enzymes, then transformed into competent E. coli DH 5 cells, as previously described . After plating on ampicillin-L-broth agar culture plates, to select plasmid-bearing clones, PCR was used to screen cloned colonies for transformants, using part of each colony as a source of the template, with the GRP 3 and 4 primers, and using agarose electrophoresis to check for the presence of a 450-bp galectin-1 band . Following PCR amplification and cloning of normal and of putative mutated galectin-1 cDNAs, each was sequenced bidirectionally by a modified Sanger technique using a 377 Sequencer (ABI) in the Sequencing Unit of the School of Biological Sciences, to confirm the expected mutated sequence, and to check the integrity of the rest of the cDNA. R49G-F: TTC AAC CCT GGC TTC AAC GCC. R49G-R: GGC GTT GAA GCC AGG GTT GAA. Forward primer for galectin-1 gene GRP3: CTG GGATCC ATG GCT TGT GGT CTG GTC (BamH I site is bold and underlined) Reverse primer for galectin-1 gene GRP4: ACGC CTCGAC TCA GTC AAA GGC CAC ACA (SaI I site is bold and underlined). Mutagenesis in Galectin-1 In the case of internal mutations, the primers listed were used in conjunction with the 5' and 3' primers (GRP3 and GRP4), to make two, overlapping galectin-1 cDNA fragments, which then were annealed and extended to create galectin-1 cDNA with the intended substitution. In the case of substitutions near the ends of the molecule, a modified version of GRP 3 or 4 was used, in conjunction with the other, normal primer, for conventional PCR amplification of the cDNA. Transformant colonies having the insert were innoculated in 3 ml L-broth/ampicillin medium and grown at 37C in a shaking incubator until the absorbance at 600 nm reached 0.8. At this stage the cultures were induced for 3 h with 0.6 mM IPTG, and then microfuged for 10 min at 5000 rpm. The cell pellets were boiled in gel loading buffer, and applied to a 15% SDS polyacrylamide gel (Biorad), to test for expression of the fusion protein. For large-scale expression, 2 litre cultures were grown and induced under the same conditions. Where protein yields were low, cultures of up to 8 litres were used. The cultures were centrifuged in a Sorvall GSA rotor at 5,500 rpm for 10 min to collect cells and the pellet was resuspended in 10 ml of ice-cold sodium phosphate-buffered isotonic saline (PBS) and extensively sonicated at 4C to lyse the cells. The lysate was centrifuged (15,000 rpm in Sorvall SS34 rotor for 20 min) and the supernatant was used for affinity chromatography. For affinity purification of the recombinant fusion proteins, a Ni-NDA-agarose column (4 ml) was equilibrated in 20 mM Tris-HCl buffer, pH 8.5, containing 100 mM KCl, 5 mM 2-mercaptoethanol, 10% (v/v) glycerol and 20 mM imidazole at room temperature. The culture supernatant was applied at a flow rate of 0.5 ml/min. The column was then washed with the equilibration buffer until the A280 of the eluant was stable, and then with 10 ml of 20 mM Tris-HCl buffer, pH 8.5, containing 100 mM KCl, 5 mM 2-mercaptoethanol and 10% (v/v) glycerol, and then with a further 10 ml of equilibration buffer. The recombinant protein was eluted with 20 ml of 20 mM Tris-HCl buffer, pH 8.5, containing 100 mM KCl, 5 mM 2-mercaptoethanol, 10% (v/v) glycerol and 100 mM imidazole . Protein-containing fractions were pooled, desalted by overnight dialysis against distilled water at 4C, and freeze-dried. Protein purity was checked by electrophoresis in SDS-PAGE, as already described. To a recombinant protein with an introduced arginine residue at the N-terminus (mutation M1R), thrombin (1%, w/w) was added, under the same conditions as were previously used to cleave GST-galectin-1 fusion proteins . The resulting protein was purified by gel filtration on a Sephadex G-50 gel filtration column (60 1 cm; equilibrated in 30 mM Tris-HCl buffer pH 7.5), to remove small peptides, and was then re-chromatographed on the Ni-NDA-agarose column, to test for the presence of the N-terminal hexahistidine tag. Erythrocyte agglutination by recombinant lectins was tested using freshly-trypsinised rabbit erythrocytes . Agglutination experiments were carried out with serial threefold dilutions of the purified fusion protein in ceramic tiles. Each well contained 100 l of 1% bovine serum albumin in 0.15 M NaCl, 100 l of 0.15 M NaCl and 100 l of erythrocyte suspension, and 100 l protein solution (1 mg.ml-1 in phosphate-buffered saline) was used to start the serial dilution. Visual identification of the endpoint of the titration of agglutination was confirmed by microscopic detection of agglutinated erythrocytes. Erythrocyte agglutination by wild-type hexahis-galectin-1 (unmodified, apart from the fusion tag) was maximal at concentrations of 100300 g.ml-1, and declined at higher concentrations. Where agglutination was not observed with a mutant galectin-1, trypsinised rabbit erythrocytes were incubated with the protein at 250 g.ml-1 for 30 min, washed several times with saline, and then used for agglutination testing with wild-type galectin-1, as described above, so as to distinguish between a failure of glycan binding, or of cross-linking by the mutant protein. WI 3 8 or GM 1604A are normal human diploid fibroblast strains previously used by us in many experiments on growth-related proteolysis. The conditions for maintenance and culture of cells have been previously described, as have assays for inhibition of cell proliferation in microwell culture plates, using an ELISA spectrophotometer to measure fixed and stained cells . In cell proliferation assays, the hexahis-galectin fusion proteins were added to normal culture media at known concentrations. For each assay series, the galectin-1 concentration was plotted semi-logarithmically against percentage of cell growth inhibition , to determine the concentration causing 50% growth inhibition (I50). This work was supported by the University of Auckland Research Committee, through the Staff Research Fund. The Animal Resources Unit supplied rabbit erythrocytes. We wish to thank Linda Adams and Julia Mount, for technical assistance in the early part of this work, and Andrew Cameron and Kong Wai Chung, for preliminary attempts to make galectin-1 mutants. Libby Hitchings and, particularly, Dr Clyde Smith, helped with molecular graphics, and Dr Cristina Weinberg continued to take an interest.
It's important to understand that when you're having your roof replaced, your home becomes a construction site. There will be roofers on, inside, and around your house. Your home might feel a little hectic for a few days, and yes, things will be messy and loud. Being mentally prepared for the mess and chaos of living through construction can sometimes be the hardest part of having a new roof installed (or any construction for that matter). Just remember that your roofer wants the job to go just as quickly and efficiently as you do. Luckily, there are a few things that you as a homeowner can do to prepare your for a residential roof replacement. First, the roofing company will deliver shingles, tools, and other supplies. They will probably bring a dumpster to your driveway for disposing of rubble and other debris. They might also bring a port-o-potty so they don't need to go inside your home to use the bathroom (and in the process, bring the mess inside). The roofers might cover up trees and other plants in your yard to protect them from debris. It's common for debris to drop in the attic or the area outside and around your home. The roofers may be using brooms, wheelbarrows, shovels, and other tools to prepare the substrate for a new roof, and this can get pretty loud. The noise level depends on what kind of roofing material is being used. Shingles that need to be nailed down will cause more noise than other kinds of roofing materials. When the project is complete, the roofers will clear the roof and the area around the home of debris. They will remove any tools and unused building materials, and they will check the area for any nails that have fallen into the yard. Preparing the space around your home for the delivery of materials can be a huge help to the roofers. There will be a considerable amount of waste, so clearing a space (preferably in your driveway, right up to the house) for the dumpster is important. This prevents litter from making it all the way to the street, reduces labor, and makes the job go faster. Making arrangements to park your vehicles down the street or in a neighbor's driveway during construction is be a good idea. Not only will this make sure there is plenty of space for the dumpster and supplies, but it will prevent your car from being damaged by falling debris. Plan ahead if you need to remove vehicles or anything else from your driveway. Clear the perimeter of your home of obstacles such as outdoor furniture, grills, potted plants, and trashcans. The general rule of thumb is to keep things 20 feet away from the perimeter of your home during roof installation. This gives the workers easier access to the work area, ensures a safer working environment, and protects your property from falling debris. If you have an air conditioning unit or home generator installed next to your house, you may want to protect it from debris by laying a piece of plywood on top of it. If you have a pool, keep it covered until the job is finished to prevent debris from making it into the pool. Finally, children and pets don't belong on a construction site. For their safety, please make other arrangements for them while the roof is being replaced. There may be a lot of vibration in your home caused by construction. You might want to remove pictures, mirrors, and other fragile objects from the walls. Even though the roof installation is outside, you never know what might get knocked loose during construction. Consider covering your clothing, furniture, and bedding as well. Roof replacement sometimes requires access to the attic. Make sure the path to the attic door is free of clutter and is not restricted. Show the project manager the way to the attic so the workers can access it if needed. Lastly, clear communication with your roofing company is imperative. When you choose E3 Roofing and Remodeling, you're choosing a company that's committed to providing outstanding service. We use high-quality materials and treat your home like it's our own. Contact us today!
This childhood classic has become an interactive, fun game for your little cherub. This Wooden Classics Shape Sorter is a great way for children to learn about dimensions, co-ordination and colours. The surface can be wiped clean and has a convenient carry handle.
Sexual Abuse, Stories, Welcome to our home! and-a-half years old. She was non-verbal and had not spoken a word since she was put into foster care. Both she and her six-year-old sister were being treated for gonorrhea. Both of their parents were in jail. That was the fall of 1981. I was twenty-nine years old. I was a trained volunteer for The Center Against Sexual Assault. I had been taking regular shifts answering the 24-hour hotline. Based on my undergraduate work as a research assistant and strong statistics background, the agency hired me as a data analyst for four hours per week at five dollars per hour. This was not the work I planned on doing forever. I figured that if I could learn some counseling skills with that agency's clientele, then I could probably handle just about any counseling situation that would come up in life. My real goal was to get my Ph.D., go into Organizational Psychology, and make big bucks doing corporate work, solving interpersonal and group problems, helping big business function more efficiently. Secondly, and more deeply important . I thought this sexual assault organization might hold some insights or answers into my nagging dissatisfaction with my religious upbringing. I thought that if there was a God, and I was asking that question at that time in my life, then surely there would be something to discover in this fringe element of the counseling profession. A few weeks after starting the job, a veteran therapist there, who knew I was in the Masters of Counseling Program, asked me if I would like to help her with the children's play-therapy group. I said that I would like to do that. The therapist explained that the half-dozen children in the group were pre-school to second grade. There were two sisters just starting the group, ages 3-1/2 and 6. The foster parents of these two girls were very involved in the kids' therapy and formed a good supportive family. The lead therapist asked me to pay special attention to the littlest girl. She was going to need a lot of help. The other children we making progress at a reasonable pace. Over those first three weeks I used what I learned in Early Childhood Development to build trust with Marie, making periodic eye contact, smiling, using a gentle voice, encouraging her to draw pictures and make choices. Session four, she was smiling back and engaging in some of the projects the other children were involved in. Then late in that session, there was a group sing along, and out of the blue, Marie joined in. The first words I heard from Marie were in her singing a joyful sound. From there she grew by leaps and bounds. The thing that drove the lesson home for me was a chance meeting two weeks later at a street fair in downtown Tempe. On a crowded sidewalk on a Saturday morning, I heard a little voice calling from behind me somewhere. I stopped and turned around, the crowd parted like the Red Sea. The little girl named Marie was running up the sidewalk calling out, "Mr. Kookendall, ( She had trouble pronouncing my name Kirkendall) Mr. Kookendall, Mr. Kookendall!" Her foster parents and sister were walking hand-in-hand behind her smiling at having surprised me. I knelt down and greeted Marie. She gave me an appropriate hug. While I knelt at eye-to-eye level with Marie, we all talked for a while. Then I watched them walk away together Marie waving as she looked back. My life changed that day forever. Something Godly had happened, and I was a part of it. I could not . I could not . I could not turn away. For me, no work in the world could be more precious. I was right. I worked saving children for 20 years. It was this time of year thirty-four years ago that I met that little girl named Marie. I imagine her now in her late thirties, and I wish I could send her a letter. Thank you . where ever you are. Thank you Marie. Music & Books, Poetry, Sexual Abuse, Welcome, Welcome to our home! things that I want to remember. Mostly I want to remember the stories. I want to remember what I learned, the people I met, the unusual experiences, and how it all unfolded. I am regularly amazed and grateful for my life adventures. I am rich with memories. Talking about my late wife Carol at the Peregrine Book Company was fantastic. It was like bearing witness, or describing a rare and beautiful phenomenon in nature, or giving a toast to her in front of my peers. I belong to the Professional Writers of Prescott. It is an organization and a monthly meeting of local authors, writers, poets, readers, all getting together to share our crafts, learn from each other, and hopefully inspiring one another to keep writing and sending out our messages in a bottle. Five of us were at the Peregrine Book Company in Prescott Arizona to tell about our Co-authoring Adventures. Herbert Windolf recalled his precious long-distance relationship with a German woman, whose poetry he translated into English. Herb, an accomplished poet himself, dazzled us all by reading a poem in German and then the same poem in English. His book is The Year Mirrored in Poems. It was marvelous experience collaborating with these writers, these kindred spirits, holy scribes, keepers of ancient traditions. I had a nice laugh with the audience when I finished my presentation by explaining that I was going to convince my colleagues Carole, Connie, Herb, and Bill to join forces, rent a van, and go on a national book tour of our own. I know it doesn't sound that funny the way I describe it now, but it really was cute and everyone in the audience laughed. As a storyteller and teacher and entertainer long ago, it felt great to be back. I spoke of my experiences co-authoring the book Without Consent: How to Overcome Childhood Sexual Abuse with my late wife Carol Jarvis-Kirkendall. I explained how our writing together was a big part of my decision to marry her. We were great together saving families. easing suffering, and sometimes helping send bad guys to prison. She had my back, and I had hers, and sometimes when people are really good together, one plus one can equal three. Our work has been a healing influence in thousands of lives. I read my popular story Marriage Decision Vision. (
Open Question: Who has just finished learning to drive a car? What was your experience like? When you first learn to drive a car, you quickly learn that the only way the car will turn is when it's in motion. If we sit in a car and turn the wheel while the car is in park, all we will get is an arm ache! God cannot direct our path without our getting ourselves in gear. God cannot use us unless we are growing in faith and practice (that is moving for Him)! The confirmation comes out of obedience along with patience and faith! Matthew responded to Jesus' radical command to leave all and follow Him. He could never return to his job, as he would be viewed as a traitor. For us as well as for them, it required steadfast faithfulness, obedience, and trust to undertake His path. Matthew actually got up and followed! This man, with so much to lose by the world's standards, left it all. Yet, he gained so much more. Matthew showed great faith by being willing to leave his prosperous position and follow Jesus to a life-from his perspective-of the unsecured and unknown. In reality, there is nothing more secure than following Jesus! Life seems like putting together a puzzle without looking at the picture on the box. We pray and hope we are doing it right, but sometimes it is like working in the dark. God's will is a mystery; there is no doubt about it. Mainly because we are not mature enough to handle the truth of what is ahead. If we do know, then we are likely to be cowards and flee! So, God reveals his plan to us slowly, just as you start feeding a toddler. You start slowly and gradually increase in the amount and types of food. Only God knows for sure what our finished life will be like; there is no final picture, only a template of trust and obedience. God does offer us the plans and instructions that we walk in His Grace by faith (see Hebrews 11). "Without Faith it is impossible to please God." So, the basic idea is for us to focus our minds on FAITH, not on worrying about the future! The great news of life, whether it seems to be a puzzle or not, is that we have a great God who cares! He seeks us out, and we sinners become His friends as He offers us fellowship and the transformation of our sickly selves to healthy, robed in His righteousness. As Christians, we are powered by the Spirit. He will change us to the core person that we can be by our response of faith. Matthew made such a response; he showed great faith to permanently leave his prestigious job, and with overwhelming gratitude, throw a big feast in Jesus' honor so his friends could see for themselves this most incredible God-Man. 1. How important is it to make good decisions while you are driving? 2. Does life seem like a puzzle to you? If so, how so? How would following Christ help you? 3. What are some of the advantages of not knowing what lies ahead in life? 4. Do you really believe, with confidence, that there is nothing more secure than following Jesus? What does secure mean to you, considering eternity versus the materialistic? 5. What is the difference to you between moving and not moving? 6. What is the difference between waiting on the Lord and moving? 7. What part does faith have in the confirmation process? 8. What is it about Jesus' words, "Follow me," that causes some to respond with passion, and others to flee in anger? 9. Follow me are two very powerful words, yet are so easily blocked when we are too puffed up with ourselves. How can you make a commitment so this will not happen to your faith? 1 Surrender your will to God before anything else. 2 Cultivate a consistent quiet time with devotions, prayer, and Bible reading. 3 Read the Word of God and let it transform your life. 4 Never forsake your responsibilities as a follower of Christ, as a family member, or in your job. 5 Discover your natural talents and spiritual gifts, then find people who are mature and have the same gifts to disciple you. 6 Discover your unique calling in life, which is usually found in your natural gifts and abilities. 7 Remain open to God's instruction and His interruptions that change your attitudes and ways of thinking. With most things in life, attitude will make the difference on how we live and respond, not only to God but also to those around us. Part of our attitude involves having the heart of a servant. Deeper thought: Follow me are two very powerful words, yet are so easily blocked when we are too puffed up with ourselves. If you think you do not need a doctor, you are very mistaken, for you would be the sickest of all. Jesus did not come for the righteous because there are no righteous people. There are only those who think they are. Their invitation to join His Kingdom will never be opened and read, because there is too much of them in the way; the words cannot be seen. The faith to respond will never grow in the shallow soil of pride.
We have win 2000 installed on these systems. First the problem came on Quality control deptt's PC's and after that is is beginning to occur on all HP pc's. We have IBM pc's also and they are working absolutely fine. We have win 2000 installed on these systems. First the problem came on Quality control deptt's PC's and after that is is beginning to occur on all HP pc's. We have IBM pc's also and they are working absolutely fine. Hi pank, Take a look at the BIOS setups in these machines. Business HPs and Dells have a setting to allow automatic shutdown and startup based on time. Another explanation is timer software; all of the computers I manage run a software timer that shuts down automatically at night. You might also want to talk to your network administrator since there are lots of management tools that allow remote shutdown of computer. It could be something they?re doing on purpose ?. There are lots of other possibilities but I would check these out first since they?re more likely. Let us know how things go and please don't forget to rate the posting. Turn the computer off, then turn it on and immediately start hitting the F8 keyrepeatedly until you see SAFE MODE. Scroll down below Safe Mode and youwill see an option to Disable Automatic Restart. Select it and rebootyour machine. Next time it boots up you will be able to read the errormessage. You'll probably need a system disc or repair disc to fix theblue screen error message. Turn the computer off, then turn it on and immediately start hitting the F8 key repeatedly until you see SAFE MODE. Scroll down below Safe Mode and you will see an option to Disable Automatic Restart. Select it and reboot your machine. Next time it boots up you will be able to read the error message. You'll probably need a system disc or repair disc to fix the blue screen error message. Depending on if you get any error messages at all. Then do the following. If you get an error message, Post it back here for more specific directions on how to fix this issue. First, remove all devices attached to the computer except the keyboard, mouse, and monitor. Then. Shut the computer down, start it, and press f8 to enter safe mode. Does the computer randomly shut down in safe mode? If not then your issue is software, and can be fixed without replacing anything. If the computer appears to shutdown and then attempt to restart without displaying an error message, do the following to disable the automatic restart on error setting. Click Start , right-click Computer , and then select Properties . Click Advanced system settings , grant permission to continue if prompted, and then click the Advanced tab. Click Settings in the Startup and Recovery section of the Advanced tab. Deselect the Automatically restart checkbox under System failure . Click OK to close the Startup and Recovery window, click OK again to close the System Properties window, and then close the Control Panel window. Disabling the automatic restart setting allows time to view the error message that displays on the screen. Contact the manufacturer of the program or device that is causing the error for specific information about the error message. this means that your cpu fan is facing some problems so its better change it or else your pc will encountered on and off. you can use it for 2-5 minutes then turned off automatically and you will notice the the lights is still on. How to automatic torn of the computer? the bios on you computer has changed get to your bios or setup screen when you turn on your computer hit deleter or F2 key it should promp you what to hit then in there their will be shut down options set it to when i hit button shut down save and exit. be carefull not to adjust any thing else. or you may drastically effect you system unless you know what you are doing. Shut off your computer and turn it back on- immediately start pressing the F8 key repeatidly until you get an advance boot menu- then go to safe mode with networking and press enter on your keyboard- See if Windows operates normally while in safe mode- If so then issue is probably a Virus. HP Compaqdc 7600 chasis fan speed is variable and mostly runs at full speed. How can I tame it down? Help! RED LIGHT BEEPING THREE TIMES I'll narrate the story of this problem. It all started when I performed a System Restore operation. The computer was performing the operation so long so I had to turn off my monitor. After I turned it on again, it was like a TV w/o a cable connection. something like gray-white particles. Then, I had to turn off my PC via the Power Button. Then this is where the problem starts -> The CPU beeps three times with the red light along with it. HELP!! Have a manual for HP Compaq dc7600 PC Desktop?
At NoveBluesky, one of the materials we are using is palmleaves aka ensansa. The palm leaves are collected, dried and in most cases dyed. Out of the leaves you weave a braid, with 4-16 leaves. When the braids are sown together they can be transformed into different items like bags, hats and rugs. It is a very common technique that most Ugandan ladies master. I'm proud to say I'm now one of them!
Points in the paint: UCSCW-28, OXY-30. Points off turnovers: UCSCW-5, OXY-19. 2nd chance points: UCSCW-14, OXY-17. Fast break points: UCSCW-4, OXY-
I have mostly lived in Glasgow with connections in Agriculture. My family used to have the surname Pratt until my Grandma re-married. Real ''Grandad'' called Alf and he has a sister called Robena. My family originally from Kent dad called Russell and I have a sister caled Amy. Live in Plymouth because dad was in the navy. I'm looking for a long lost family friend. Both my sister and I grew up with her daughter.I'm in my mid-thirties now studying a degree. I'm married and have a little boy who is 3yrs
For most homeowners, finding a way to interject a bit of fun into their residence is a main concern. There are a number of things that can be added to a home to increase the fun in the residence, which will require the owner to do some research. Among the most popular fun additions to a home is a ping pong table Calgary. In order for the right table to get purchased, a homeowner will have to find the right suppliers in their area. The following are a few tips to use when trying to find the right supplier for your ping pong table needs. The first thing to look for in a ping pong table supplier is their knowledge of the products they carry. For most homeowners, finding the right table is a chore due to their lack of experience with them. By finding a supplier with experience, a homeowner will be able to find their perfect table. Make sure to take some time to research the suppliers in an area to figure out which one can best meet your needs. What Type of Selection Do They Have? The next thing you need to consider when trying to find the right supplier for your ping pong table needs is the selection they have. You want to make sure that you have plenty of selection when it comes to choosing the right table. The more you have to choose from, the easier your decision will become and the better equipped you will be to find the right table. The last thing you want to do when trying to find the right ping pong table is to be limited on the options you have. Another very important thing you have to consider when trying to find the right ping pong table is the price you will be able to get it at. In order to find out what the best price on the table you want is, you will have to go online and get an idea of what they are going for. The more you are able to find out about the price of the table you want, the easier you will find it to get a good deal. The time that goes into this type of research will be more than worth it in the end. When in need of a great ping pong table, be sure to call on the pros at J & J Service Tech. They have the selection and the prices that you are looking for. Call them or go to their website for more information.
Think of this time as a great opportunity it's like the New Year Resolutions of homeschoolers. We're out with the old and in with the new. And with that always comes a time of reflection, of celebrating being done, and also making resolutions/goals for the upcoming year. And just since we're already going there, I want to point out this article that I just read today. WOW. Powerful stuff. But really, has the "homeschooling" become the driving force in all that you do in your home? Sadly, I've seen several "discussions" online that give me pause. Maybe because I'm led a Bible study in past years, entitled "No Other Gods" that I'm hypersensitive about this particular topic?
We retired people eat out. And we eat out often. I never ate a meal in a restaurant as child. It just wasn't done. It was probably related to having five children in the family and being relatively poor. We were all skinny. This was before Mc Donald's, Burger King, and Pizza Hut existed. Living on an acreage in Iowa we produced most of the food we consumed. There was the large garden that provided vegetables that were eaten fresh or canned for off season meals; the orchard provided fruit and nuts. Then there was Granny, the cow that supplied the milk; the chickens gave us eggs and meat and hogs provided the pork. When I think about it today, I realize that it was an organic diet. At that time we just called it growing our own food. Not because it was healthy but because it was inexpensive. For whatever reasons eating out has come to play a major role in our lives. Retirement and eating out certainly seem to go together. Thus retirement and gaining weight seem to go together. That's a problem. Last week we had three invitations to dinner in three days. This meant three days in a row of eating too much. I have little to no resistance to consuming every thing set on a dinning table. My wife has learned to prepare only just enough. She knows that if she prepares more, I will eat more. We all know that pounds go on much easier than they come off. I know it seems arrogant to complain about too much good food, but as mothers tell children too much of a good thing can ruin you. Don't get me wrong. I love eating good food. My wife is an excellent chef. She grew up on a farm and learned to cook wholesome, home grown food. She had four brothers and a farming father to help feed. She learned cooking hardy and healthy food. She got an undergraduate degree in Home Economics and went on to refine her cooking skills at La Verenne, a French cooking school in Paris. For nearly fifty years our evening meal has always been carefully prepared, slowly consumed and enjoyed. Food is important to us. Now that we're retired our interest in food has continued. We have friends with whom we exchange dinner invitations on a regular basis. The 'ore doerves, the wine, the salad, the main course, and then the delectable desert are always savored and discussed. On top of the evening dinners there are the lunches. It is so easy to say, or hear, "Lets do lunch". Then it's off to the restaurant. Overwhelming temptation greets us at the door. Too many calories are sure to invade and find lodging. That is a problem. When we retire or age, our metabolism slows. We all wonder why our appetite doesn't also decline with aging, but so far that has not been my experience. The appetite is as healthy as ever. When I was a child a double dip ice cream cone was my daily dream. If only I could afford to stop at the "The Highlight" cafe for a chocolate rocky road. That would make my day. As a youth, metabolism was not a problem; money was. Retirement reverses the situation. Just when your wallet can afford a double dipper on a daily basis your waist line can't. "Watchful eating" is the only answer to the dilemma. You have to watch what you eat. I know that some books talk about going to a low carbohydrate diet, or a low protein diet, or a you fill in the blank diet. Book shelves are jammed with the secret to a healthy diet. I'm not sure it matters much what you eat. Personal experience tells me that it is the quantity of food I eat that matters. The scale has become my dictator when it comes to weight gain; that and my belt. Every day the scale shouts up to me from the floor. It tells me if I've been good or bad. It tells me if I can indulge or if I must cut back. And just as important is the belt. I like to think the leather has shrunk but I know that's a lie. As a child, when my father swung the belt, it resulted in me changing my behavior. Today, it is just a matter of not being able to buckle the belt that changes my behavior. I interviewed this guy once who makes chocolates; fantastic chocolates. He is a chocolatier in the true sense of the word. He not only makes them but he eats chocolate for breakfast, lunch and dinner. He is not over weight. He claims doctors are going to be very interested in his body when he dies. His cholesterol is low. His weight is under control. Time has passed. He is now probably in his early fifties. I saw him a few weeks ago and he looked great. I'm envious. How come I can't do that?
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The Coalition has again failed the fairness test when delivering its Mobile Black Spot Program (MBSP) Round 3. Shadow Minister for Regional Communications, Stephen Jones MP, criticised the lack of transparency and clear, evidence-based decision making in defining the Government's Priority Locations list. "There is no clear or transparent process for determining these Priority Locations. Instead, the Government is using Round 3 to deliver on the Coalition's 2016 Election commitments when critical locations in bush-fire prone areas are missing out. "The Australia National Audit Office (ANAO), Productivity Commission and Australian Consumer and Competition Commission (ACCC) have all expressed concern at the administration of this program. "Priority should be given to funding mobile black spots based on consultation with stakeholders such as State and Local governments and emergency services experts; and in response to evidence-based criteria.
What are the best and the coolest chairs for teenagers? Teenagers LOVE having cool and funky furniture in their bedrooms! One of the best 'furniture gift ideas' for a teen is a cool and funky chair! As the mother of a teenager myself, I am always looking for cool stuff for my daughter's bedroom and I found some pretty cool chairs for teenagers being sold online! My ultimate favorites are the fashion and girly high heel shoe shape chairs for girls! *By the way my teenage daughter just bought this cool 'Bunjo chair' for her bedroom and I gotta say it's awesome!! It actually supports weights up to 225 lbs! Cool Chairs for Teenage Girls! I have to start my selections with this super cool, funky and fashion zebra print high heel shoe shape chair! Isn't it absolutely perfect for a teenage girl's bedroom? Even better if she already has a zebra comforter or curtains! This cool chair is not only super fashion and FUN, but also very comfy to sit down and read, watch TV or listen to music! How cool is this Leopard Print High Heel Chair? I had to show the leopard print one too! If your teen girl loves leopard stuff then I guarantee she is going to go nuts when she gets this cool high heel chair for her bedroom! How about a Fun Mitt Chair for your teen? We can't talk about cool chairs for teenagers without including a fun mitt shape chair too in the mix! What I also love about this funky chair is that it's available in seven fun colors, besides this gorgeous bright green one! It is perfect for teen boys and girls! The Coolest Chairs for Teenagers! Teens also love these fun animal 'paw shape' chairs and this leopard print one is my favorite! Won't it look super cool in your teenage daughter's bedroom? Gosh I also want one for myself! How awesome and ultra-cool is this light blue and zebra funky chair for tweens and teens? You can also choose it in hot pink and zebra! It's very easy to clean and very comfy! A happy mom buyer said it's also sturdy and a fantastic chair! Very Cool and Useful Royal Blue Sleeper Chair for Teens! Best Chairs for a Teenager's Bedroom! I love this gorgeous royal blue sleeper chair for a teen's bedroom! It was made using high density foam and it converts to a very nice bed! Perfect to create a cheerful corner for reading, relaxing and listening to music! I love the fact that it is also a cool 'sleeper'! Cool Bright Orange Bean Bag Chair for Teens! Teens also LOVE cool bean bag chairs, and as you can see this large bright orange one fits three big teenagers! When I was a kid I used to love lying down on these cool bean bags! Best Chairs for Teenage Boys! If you are looking for the coolest chairs for teen boys, then I really recommend this awesome wireless gaming chair! This cool gaming chair for teens is basically compatible with all video-game systems, MP3 and DVD players! As you can see it comes with a cool side control panel where they can adjust the volume, bass and it also has input and output jacks. This chair also has an ergonomic design that offers complete back support while your teen is playing his games! It also swivels and tilts and they love that! Buyers say the sound is awesome! Best Gaming Chairs for Teen Boys! They are fun, comfortable and they look great anywhere! This oval chocolate brown saucer chair can be for a teenage boy's bedroom or girl's. Buyers all say this chair is so comfortable that they feel like like are sitting on a cloud! Modern RED Kiss Sofa for Teenage Girls! How cool is this bright red kiss lips shaped sofa chair? I think it's perfect for a teen girl's bedroom! It's so fun and daring! How about this Fun Pink Futon Sofa for Teen Girls? This cute light pink futon sofa chair is perfect for a teenage girl's bedroom or dorm room! It's super lightweight and it turns into a nice and cozy bed in seconds! Colorful and FUN Futon Chair Recliners! Best Chairs for any Teenager's Bedroom! These gorgeous and very stylish, comfy and colorful futon chair recliners are the best and the coolest floor chairs for a teen's bedroom! They are absolutely perfect for playing video-games, watching movies, listening to music, reading or just talking on the phone with their friends! They look very cool anywhere and they are extremely durable! You can take them with you anywhere too, to guarantee a nice and comfy seating place! *I hope you enjoyed my selections of cool chairs for teenagers on this page! Best Gifts for 17 year old girls!
The fight against slugs and snails is a bitter one and is usually a lost cause. Methods, including home remedies, that focus on killing slugs only fight the symptoms and do not alleviate the causes. Such methods are not the sustainable solution desired. An alternative way is to use means that control slugs indirectly. They are not only more peaceful but also more effective than methods that harm them directly. 4.1 Scissors and Spades: A Quick, 'Humane' Death? 5 Is It Necessary to Kill Slugs and Snails? 7 Can Slugs and Snails Suffer? When slugs and snails are eating seedlings and newly planted vegetables overnight, not only are plants harmed but the gardener's heart is also damaged. After a period of mourning comes anger and with it the desire for compensatory justice. Plans for revenge are forged and war on slugs is quickly declared. Fighting seems the only solution. Is it necessary to kill snails and slugs? Does it lead to sucess? In my experience, most slugs and snails have a high level of perseverance. They usually succeed in thwarting all attempts to get rid of them. Even if all the slugs in a garden are killed, others will arrive from elsewhere to fill the gap after only a short while. Oddly enough, they seem to be even more numerous in gardens where a tough fight against them is waged. I have not yet heard of any gardener who has managed to eradicate slugs from his garden by force. The slug population seems resistant to poison and able to withstand every single attack with scissors and spades. The fight against slugs can end in despair. At worst, this war leaves gardeners feeling desperate and hopeless. Some have even stopped cultivating vegetables. In my opinion, this is a shame, and this is one reason why I have created this project: it is exactly these desperate people that I wish to help to find new ways of slug control. I aspire to lead them to success by turning their violent fight against slugs into a more cautious campaign to protect their plants. The methods of destruction presented here are the wrong approach; there are more sophisticated alternatives. A boom in the slug population is always a sign that the natural order of things is out of kilter. By killing snails, all you do is fight the symptoms; you leave untouched the underlying causes of the problem. The natural equilibrium will be even more disturbed because killing slugs also harms their natural enemies. Nonetheless, below I briefly present some of the typical methods used and try to explain why they are doomed to fail. I go on to present effective alternatives. Is there a 'humane' way to kill slugs and snails? Scissors and Spades: A Quick, 'Humane' Death? Cutting slugs with a pair of scissors or splitting them with a spade are perhaps the most widespread methods, apart from trampling them to death. This quick death is considered 'humane' and the least painful way for the animals to die. Not only is respect for life often forgotten, but frequently the dead slugs do not get buried. The smell of rotting snails and slugs is a powerful attractant for all conspecifics in the neighborhood. With this method, if slugs and snails are not buried properly, even more can find their way into the garden. I am firmly against this and think there are much smarter ways to protect plants. But if killing is the method of choice, at least you should give the slugs a dignified burial. Slug pellets contain several chemicals. There are various slug and snail poisons called molluscicides. Typical are pellets that contain metaldehyde or iron phosphate to kill the slugs. All other pesticides have been banned because using them kills beneficial earthworms and other animals. The poison could also be dangerous for humans and pets, and for other beneficial animals in the garden. Using poison makes it impossible for nature to heal and for natural balances to form. Metaldehyde is toxic to children and pets (dogs, especially, like to eat the pellets), so must be handled with great care. The pellets should not be touched with bare hands. Slugs and snails are attracted by substances on the blue bait. After eating the metaldehyde, they try to flush the poison out of their body, thereby losing body fluid and drying out painfully from the inside. This usually takes many hours and if it rains they might even survive this fight. Slugs will usually die close to the spot in which they came into contact with the pellets. After dying, they have to be collected, as otherwise their smell will attract more slugs from all around. After the slugs have eaten the bait, their digestive system becomes blocked, they can no longer eat, and they starve slowly. This can take several days. During this time, they stop eating but are still able to reproduce. The slugs retreat to a sheltered place, where they die unseen. Their dead bodies then attract new slugs and snails into the garden. Products with iron(III) phosphate are approved for organic farming, but their effect on beneficial earthworms can still be dangerous. Apart from that, the slow death, the possible reproduction and the attractant effect of the dead slugs make this method highly questionable. Slug pellet manufacturers are pleased because this is not a sustainable solution at all. The pellets work for a short period only and have to be applied again and again year after year. This costs a lot of money and might lead to further despair. I therefore recommend staying as far away as possible from slug pellets! You might even discuss their harmful effects and better alternatives with your neighbors. You will find more information here: Slug baits and pellets. Salt can ruin soil and damage plants. If you sprinkle slugs and snails with salt, it will bind their body fluids and their bodies will dissolve slowly. This is perhaps the most unpleasant way to kill them. Nevertheless, many gardeners still use salt in their gardens. They either sprinkle it on all the slugs that they find in their beds or they use it to kill the slugs they have collected. This method shows little compassion and the slugs must experience significant suffering. I cannot understand this approach. Some gardeners use salt to create barriers for slugs and snails, which is even worse. In most areas, applying salt in the garden is forbidden because not only does it ruin the soil and damage the slugs, but it also kills all living beings that come into contact with it, even plants. Some Europeans like to eat snails. An equally cruel method is to pour hot or boiling water over the collected slugs. Supposedly, this is another 'humane' way of killing them, but hot water is an excruciating death for slugs. Some people freeze slugs and snails to death. Putting slugs and snails into a plastic bag and then into the freezer is also described as an 'animal-friendly' killing method. It is believed that slugs and snails will slowly die in the freezer bags, just like they do in winter from harsh frosts. I doubt, though, that this is a pleasant death. Laying beer traps is still a widespread method for controlling slugs. However, word has spread that in the end, beer attracts even more snails and slugs from far away. In theory, this method seems to work just fine. The traps are quick and easy to set up. The slugs come out at night, drink the beer and some of them fall into the fluid and drown. So, this is presented as a painless way to kill slugs and is embellished as a 'wonderful' way to die drunk and happy. In the end, however, only a few slugs fall for the beer, but many more are lured into the garden. Roundworms also called nematodes are parasites that infest snails and slugs and feed on them until they die from bacteria produced by the worms. Nematodes live underground and are sensitive to light and dry conditions. Therefore, they only infest slugs and snails that live inside the soil. So, nematodes can be used against field slugs, which sometimes live underground. However, they cannot be used against slugs and snails that only live on top of the soil, such as Spanish slugs. Being eaten from the inside is awful to imagine. This method is not sustainable, because once the slugs are gone the nematodes also die or leave the garden. In addition, nematodes are quite expensive and there are cheaper ways to deal with slugs and snails. Natural enemies can keep slug and snail populations in check. This is the only method of killing slugs and snails that I recommend as useful and applicable to any garden. Attracting natural predators into the garden is a sustainable and environmentally-friendly measure that leads to long-term success. Apart from natural enemies, there are, for example, domestic animals that eat slugs, such as chickens or runner ducks. These animals feed on slugs and snails and look for their eggs. Chickens, turkeys, and ducks are usually quite interested in this kind of protein snack. Of particular importance is the insect world, because many insects eat snails. Not many people know this, or they have forgotten. The slow and almost defenseless slugs are eaten by all kinds of predatory insects, such as ground beetles, marsh flies or harvestmen. The sharp decline in the insect population might explain why slug booms are becoming more and more common. So, it is important to help as many insects as possible to settle in your garden. Many ground beetles are professional slug hunters. This is why it is useful to lure as many animals as possible back into the garden. If you increase the biodiversity in your garden, you can prevent all kinds of garden pests. In addition, you can help leopard slugs (Limax maximus) to settle in the garden. These are predatory slugs that also kill other slugs and snails; for example, the Spanish slug. Is It Necessary to Kill Slugs and Snails? In my opinion, it is not necessary to kill slugs and snails using any of the methods described above. There are much wiser ways to deal with the pests. You do not need to fight them directly. It is enough to ward them off passively; for example, with barriers against slugs and snails. One intelligent way is to select flowers and vegetables in which slugs and snails show little or no interest. Some vegetables that you do not want to miss are on the list of favorite foods for slugs and snails. However, there are also many flowers, vegetables and herbs that they do not like to eat. There is also an entirely different approach. You can create a sacrificial bed to distract slugs and snails from the plants you want to save. Their greed is best met with generosity. They can then be found in these beds and collected easily. Although this may be difficult in small gardens, it could contribute to successful slug control overall. Which plants do slugs like? Blackbirds eat earthworms and slugs. The method that helps immediately is to collect and relocate the pests. It is best to use snail and slug traps in which they are caught alive. The world is big enough for snails, slugs and humans. There are many places in the environment where they will not disturb anyone. Nature does not recognize discrimination. However, it is reasonable to be concerned about local ecosystems being disrupted when slugs are relocated. So, you should only put them in spots where they already exist and in places with high biodiversity. That way, there is no danger of spreading them all around and nature will take care of them. It is not enough, however, to throw the collected slugs just over your garden fence. They can travel up to 25 yards (22 meters) per day. This is why they might come back if they are not put far away. I recommend putting them at least one mile (1500m) or, even better, a couple of miles (kilometers) away. This snail was probably killed by a beetle. Can Slugs and Snails Suffer? When thinking about killing slugs, one question inevitably arises: To what extent do they suffer? Slugs and snails should be treated with dignity and respect, but this is too often ignored. It is easy to put yourself in the position of other mammals and realize that they can and do suffer. They scream and squeal when in pain and can even whine, just like humans do. Slugs and snails do not make comparable sounds. They seem to endure everything quietly. This makes it harder to recognize their pain and to treat them with compassion. However, if you observe slugs more closely, you soon realize that they can experience suffering. For example, the video about electric slug fences shows how sensitive they are to pain. Many gardeners, therefore, try to kill them in a 'humane' way that makes them suffer as little as possible (scissors or freezer). Unfortunately, some gardeners are unwilling to give up killing entirely, unaware that there are other, better, options. My wish is that in the long term there will be a rethink; I have already observed the first signs of this. Perhaps there will come a time when even mollusks will be granted personal dignity and the right to live. 4.7 (93.33%) 3 votes - Glad you are here. found this site but, unfortunately found it after trapping 51 big slugs with beer. I would rather be more humane. Those fifty-one slugs were captured last night. Many of them had white globs of flesh outside their bodies. Are these lungs? which were pushed through the body by drowning? Unfortunately, I cannot answer your question. Maybe someone else who reads this could help. Here you find more information about slug traps without beer. Good luck with humane slug control!
The Richmond District never ceases to amaze me. Yes, it is mostly consumed by rowhouses. PLUS, there is so much more! For starters, there are three very larged houses of worship. and St. Monica's Catholic Church. a most tasty cup of spicy chai. And the Sewing Workshop that must be doing gangbuster business right now because everyone I know has recently purchased a sewing machine. Sewing is the new knitting, apparently. Check this place out if you want to learn how to sew. and my little friend who I met on my Central Richmond walk back in February! Looks like he's moved down the sidewalk a little. And it looks like there's a new Sara to forget . See - wasn't that a fun neighborhood?! Love the pic of the extended shadow. Would you mind if I shared that on my blog? Thanks, Sarah! I wouldn't mind at all - share away! Be sure to dip into Argonne Nursery School/ Garden when you get to 16th Ave and Cabrillo. Can I join you for a walk one of these days?
: Your brother stole a journal. Your little brother has stolen your journal, find him before he opens it. Use the arrow keys and space bar to play this game., Category: Fun Games . Created: 2008-06-24 10:54:45 , Updated: 2008-12-25 21:21:46 , Brought to you by: Samar Games * Please, Wait for downloading the game - File size is 1.16 MB - Takes 1.9 Minutes .
Roadworks that have been causing problems for nearly two months for drivers in Burton town centre are set to finally be cleared this week. Temporary traffic lights were installed at the junction on Station Street, Union Street and Guild Street in February and have been causing long delays for motorists in the area. The traffic lights were initially installed at the start of February while work was carried out by Western Power Distribution to install a new connection to Burton's former county court in Station Street, which is being redeveloped for apartments and a yoga studio. After that work had finished, work then started on locating and fixing a gas leak in the road by gas company, Cadent. The work has been underway since the beginning on the month and looks as though it will finally be cleared on Wednesday, March 27. Details about the repairs on roadworks.org say the work is being done to "trace, then excavate to repair gas escape and reinstate where possible", and says the work is expected to last until Wednesday. Cadent has been contacted for further comment. Business owners in the area have had mixed reviews on the closure. James Weeks, who runs The Dial bar and restaurant, said: "The hole has just been left empty and I've not seen anyone working on it for days and days - you wouldn't get that in a city. "I will definitely be glad to see it gone - last week my wife got to the Intu centre in Derby before I got to work, which is usually a six-minute journey! Business has not been as positive at Brews of the World however, as owner Robin Ludlow, 42, said sales had been significantly down on weekends. He said: "We have had a total lack of communication. I've been asking the men outside about what is going on but the problem is they only know what they're doing - a lot of it seems to have been contracted out by different companies so they all don't know what the others are doing. Sue Dorling, managing director of the Alphabet Gift Shop, said: "I think the roadworks have had more of an impact on staff than anything! "We didn't get any warning about what was happening and we have had to guess about what is happening. "A lot of the time people haven't been working there and I think that is what is most frustrating for people. "I don't think it has really affected our business though, which is a positive."
Now we must configure Apache so that it can handle Python files. There are two ways of doing so. The first (and default) one is to use the Publisher Handler. It allows you to write pure Python scripts with the extension .py that will be interpreted by Apache. The second way is the PSP Handler. PSP stands for Python Server Pages. It allows you to embed Python code directly in HTML code, similar to PHP. PSP files have the extension .psp. Please note: if you use ISPConfig (from version 2.2.24 on) on the server, please leave out the <Directory . >. </Directory> part in the above file since that would enable mod_python globally for the directory in question. In ISPConfig you can enable mod_python on a per-website basis instead which gives you more control whether a website can use mod_python or not. and call it in a browser (e.g. ). If all goes well, it should display Test successful in your browser. Please note: if you use ISPConfig (from version 2.2.24 on) on the server, please leave out the <Directory . >. </Directory> part in the above file since that would enable mod_python globally for the directory in question. In ISPConfig you can enable mod_python on a per-website basis instead which gives you more control whether a website can use mod_python or not. Also note that ISPConfig does not support the PSP Handler - it uses the Publisher Handler. and call it in a browser (e.g. ). If all goes well, it should display Hello! in your browser.
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Anyway. yeah. More soon. Yay for all you recently-starting OT students.let me know how things are goingI'm guessing overwhelmingbut I promise you can get through it! If you need a pep talk/morale booster really bad, e-mail me or commentI can be a good cheerleader. IT WILL BE OKAY! Alright I'm up way past bedtime. Gotta be up in six hours. Good night.
Welcome to Bye the Bay Bed and Breakfast at Rondeau Bay. This is a lovely location in the best birding region in Ontario. Located a 10 minute walk to Rondeau Provincial Park and the sandy shores of Lake Erie. This bed and breakfast offers a warm and friendly atmosphere in one of Ontario's most beautiful recreational areas. If you are a seasoned BnB veteran, you will love the privacy and service provided. If you are new to BnB's, then this will be a delightful experience with a welcoming atmosphere and friendly service.
This is where it all starts. Good design. Our design engineers have over 25 years of special purpose machine design experience. We use cutting edge 3D CAD software to take ideas from the whiteboard and turn them into creations. Good planning and good design saves time and money on the workshop floor. Whether its a complex production line machine, an architectural marvel or a piece of bespoke furniture, we get it right; first time.
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Home > Resources > Blog > May 2017 > Election 2017: What Do the Conservatives Say about Workers, Employment and Recruitment? The General Election is now less than a month away, and all of the main parties have published their manifestos in full. Here at Love Success, we're going to be looking at what the main parties are proposing for the country over the next five years, with a focus on workers, employment, and how the new laws might affect PA and secretarial recruitment agencies, office support jobs, PA roles, and receptionist positions. We've already taken a look at what the Labour party is offering next up are the Conservatives, who have a large poll lead and look set to remain in government. The guarantee that workers will have the same rights after Brexit as they currently enjoy under EU rule. An increase in the National Living Wage until the end of parliament, with the figure expected to rise in line with median earnings every year until 2022. Protections for workers in the 'gig' economy, to prevent them from being exploited by employers. Workers on company boards. Allowing workers access to information on their company's future (the same access as shareholders might receive). New rights to request leave: one for training, one for child bereavement leave, and one new statutory right to leave work for one year and care for a relative (unpaid). New pension protections (in the wake of the BHS scandal). An extension to the Equalities Act, which will now protect those with mental health conditions. Despite announcing the new plan to protect workers' rights, there are no plans in the manifesto to abolish tribunal fees, which some experts have claimed will prevent the rights from being enforced. Businesses who wish to employ a skilled worker from outside the EU currently pay a charge of 1,000 the Conservative manifesto proposes increasing this to 2,000 per employee. The Conservatives will create an investment fund to boost the UK's lagging productivity, with 250m in funding allocated to increasing skills by 2020. The Conservatives have already introduced the Apprenticeship Levy, and in their manifesto their state that they remain committed to creating 3m apprenticeships for young people by 2020. The manifesto also promises discounted public transport for apprentices -to ensure that they're not deterred from taking up an apprenticeship by the cost of travel. So that's what the Conservatives are proposing for workers and employers should they make it back into Number 10. We've already covered Labour's manifesto, so next we'll be looking at what the Liberal Democrats' proposals are for the world of employment. Keep following the Love Success blog for the latest updates, as well as the latest receptionist opportunities, London PA jobs, and temporary PA jobs! No comments on "Election 2017: What Do the Conservatives Say about Workers, Employment and Recruitment?"
Location: Playa Ocotal, Rivas, Nicaragua. The eco-resort is a detailed celebration of Nicaraguan nature, materials and culture. An experiential architecture that comes out of the wildlife of the area, inspired by it and, as much as possible, hiding within it. The eco-lodge was designed to have as little impact on the natural beauty and wildlife of the area, the use of natural materials helped incorporate the bungalows and villas into the forest. Each cabin was raised on stills with the purpose that the buildings would never interfere with ground-level wildlife. With 15 bungalows and 3 villas tucked into the lush jungle, reflecting a whimsical feeling of privacy and seclusion. Custom design furniture pieces were made to highlight the eco-lodge's culture, sustainability and natural luxury. The bungalows have a natural privacy given by the surrounding forest with an outwards towards the bay and the expanse of the Pacific Ocean. Thatched roofs, that blend into the setting, and benefit from the indoor/outdoor style that works so well for nature-lovers, each bungalow includes private outdoor showers, a plunge pool and, in some cases, trees growing through the roof. Some of the highlights are the covered outside terrace featuring a custom design hanging daybed, large bathrooms with handmade taps from copper tubing and the 110-meters suspension bridge that connects the hillside bungalows to the main building, without interfering in the wildlife's path to the estuary. At its heart, Morgan's Rock is a luxury conservation project that covers 1,800 hectares, and has been involved in the planting of more than 2 million trees, the reintroduction of animal species, protection of wildlife, and the initiation of sustainable agriculture in the area.
Here at paleo plan, we love our seafood. explore some of our favorite paleo fish and seafood recipes. we recommend wild-caught or sustainably raised options to cut down on heavy metals.
Registration is now open for Little Falls Youth Track and Field (Kindergarten - 8th Grade). Practices are Sundays April 7th-June 16th. 25.00 per child. Registration deadline is April 5th. Any Questions contact Patricia Swaney. To register go to leaguelineup.com/LFAC.
Navy is the new black of my work wardrobe. Styling my favorite navy polka dot pants and sharing why I prefer navy or black! Once I graduate grad school, four years ago, I started building my professional work wardrobe. I made a list of all the clothing items, accessories, shoes that I needed for my professional wardrobe and worked my way finding those items. As I curated my work wardrobe I quickly realized I prefer navy over black. Now don't get me wrong, I own the classic black pants, blazer, and skirt however I rarely reach for these items. I find black to be too harsh of a color on me. Navy is the new black and I find it to be a great alternative to black. I find that navy can easily be styled with an array of colors. My favorite combos are pink/navy, green/navy, yellow/navy, and the classic white and navy. The newest addition to my work wardrobe are these pairs of M. Gemi Navy Suede pumps. I have been wearing them non-stop and can't believe how comfortable they are! I love the classic silhouette and know it will last for many years.
Hama/Sweida, SANA-Units of Syrian Arab Army operating in Hama countryside pushed ahead with military operations against dens of terrorist groups along the administrative border with Idleb province, inflicting heavy losses upon terrorists. SANA's reporter in Hama said that army units carried out intensive operations against sites of "Turkistan Party" affiliated to Jabhat al-Nusra on the eastern side of al-Ghab plain in the villages of Waset, al-Mansoura and al-Ziara. Scores of terrorists were killed and others were injured during the operations, in addition to the destruction of terrorists' sites. The reporter added that the army directed artillery strikes on the frontlines of al-Nusra to the northwest of Hama, destroying a number of their sites in the area surrounding Kafr Nbouda and Tal al-Sakhar. In the northern countryside, the army's artillery raided positions of the so called "al-Ezza Battalions" in Maarkaba and al-Latamina, inflicting heavy losses upon terrorists' ranks and equipment. Units of Syrian Arab Army continued advancing to cleanse Sweida Badia (Desert) from Daesh (ISIS) terrorists. SANA's reporter in Sweida said that army units, backed by supporting forces, advanced in the direction of Sad al-Zalf, Toluol al-Dab'a, al-Dabia, Alam, al-Safa and Arad al-Keraa, establishing control over new areas in the depth of 40 km in the eastern countryside of Sweida which led to enhancing the security in the area. The reporter added that army units eliminated a terrorist group in Arad al-Keraa and chased their remnants as heavy clashes erupted in the direction of Toluol al-Safa which is one of Daesh main sites in the area. In parallel with the clashes, the army's artillery and Air Force launched strikes on Daesh positions in the area, killing many of them and destroying their vehicles and equipment. Meanwhile, the army's engineering units continued combing the recently liberated areas and dismantled a booby-trapped BMP vehicle and hundreds of IEDs and mines in addition to the destruction of a car bomb left by terrorists in Arad al-Keraa. Later, an army unit destroyed a den for Daesh in Beir Hasan area to the east of Khirbet al-Ambashi, killing 13 of its terrorists and injuring dozens.
At 25, West-End dancer, Ellie Wakefield should be having the time of her life. The only problem is, ever since waking up in a leaky cellar belonging to three hundred year old vampire, Will Austen, she's been very much dead. And to make matters worse, she's since found that an aversion to blood and a fear of the dark aren't very helpful - especially when you're a fledgling vampire. William James Austen has fallen hard. He's spent the last year loving Ellie from afar and now he's finally able to be truthful about who and what he is. As the most powerful and revered vampire in London, he's used to getting what he wants. But this time, Will might just have bitten off more than he can chew. Wow I absolutely loved this! I had obviously read the synopsis, but had no idea just how much I was going to enjoy it! I must admit I was a teeny tiny bit skeptical about this as it was back in the world of Vampires and I wasn't sure how it was going to stand out and be different. But I am more than happy to say it was a fantastic Vampire story in its own right and I liked being back in fiction world of Vampires after given it a wide birth when Vampire fiction exploded. Berni writes brilliantly. Within the first few lines I was completely hooked and every single page was unputdownable. I loved Ellie as a character and really felt like I stepped into her shoes whilst reading this. She was a feisty, strong and knew her own mind and I don't think Will quite realised what he was taking on when he turned her into a Vampire! Oh and speaking of Will! Sigh! Wow what a man/vampire! A new book boyfriend for me definitely! Along with Ellie we learn that the Vampire world is a dangerous one; they aren't just a danger to humans and this made for some very gripping, heart stopping reading! The story is mostly told from Ellie's point of view, but I really liked that we got snippets of what Will was thinking through his diary entries. I love getting all main characters points of view. I really really really hope their is a sequel to this, as even though there is no real cliffhanger at the end, I felt like I could have continued reading. I want to go back to Ellie and Will's world. A gripping, absorbing and unputdownable book. I cannot wait for more from Berni! Laura, thank you so much for that lovely review :) You have really made my day. Just between us *grins* there are more books in the series too. There's a sequel with a wedding and a third book featuring Stevie's romance with back up from Will and Ellie! Thank you for featuring my book on your lovely blog.
PWG respects your privacy. None of the attendees allowed us to show their personal data. Please be aware that Google will not accept walks in. We hear a lot about Design Thinking, but what exactly is it? Join us for an interactive workshop at Google Zurich to Decode what Design Thinking really is. We will learn from the Google UX team about designing products. We'll work together in small teams and learn how to solve the users' needs using the Design Sprint methodology. We'll also discuss how we can apply this process to a challenge of your own. Mirjam Seckler is a user experience researcher, lecturer and writer with a PhD in Cognitive Psychology from the University of Basel. Before joining Google in 2015 she worked for start-ups, in academia and for a bank where she helped product teams learn from their users to build compelling user-centered products and services. As a UX researcher, Tanja's job is to bring the user's perspective into the product and knowing what questions to ask, when and to whom. At Google she is using both qualitative and quantitative methods to improve the user experience for travelers. Tanja's background is in Psychology, Anthropology and Computer Science and she has worked on research projects across the globe on topics such as privacy, automotive, video advertising and e-commerce. Chrys has a Master's in Human-Computer Interaction from Carnegie Mellon University a Bachelor's in Computer Science from the University of the Philippines.
Introducing the world's most detailed printed Iron Man Lego figure! Featuring 360 degree UV Printing, this figure is ideal for the ultimate Marvel collector and Lego enthusiast. This figure is based on the Mk 50 Iron Man armor seen in Avengers: Infinity War. The figure comes with a double-sided head made by Lego, along with the official Lego Iron man helmet. The body is a custom print made with UV Printing.
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To deal or post orders on FIOB, you will need to use a stockbroker, the procedures for which will vary from firm to firm. There are 3 options available to you. There are a number of third party brokers who are already registered to trade on FIOB on behalf of their clients. Brokers who are not already approved to trade on FIOB can become registered. Contact your broker to advise that you wish them to deal on FIOB on your behalf and they will get in contact with
12 rangs 30'' / 3 pts. Stack Fold , repliable . 2 vis , 98" , chute Semi-Ind. 92" chute S.I. , Lame arriere
SRAM's F.K. Day, president of World Bicycle Relief, said: "With this facility, we are able to expand our geographic coverage beyond the area around the capital of Lusaka. We are well on our way to training 400 field mechanics throughout the country, and are currently delivering between 300 and 500 bicycles per week." The 2.9m programme will provide over 20,000 bicycles to volunteer, community-based HIV/AIDS care givers and disease prevention educators in Zambia in the next 12 months. It also includes training of youth and adults in bicycle maintenance and life skills, and improvements to the local bicycle technologies. The bicycles will be assembled in eight locations across the country. Day said he was encouraged by President Bush's recent request for 30bn to combat HIV/AIDS, and believes bicycles can be a key component in the battle against the disease. "Simple, sustainable mobility in the form of bicycles is an essential tool in the fight against HIV/AIDS," said Day. "There is a strong link between disease and poverty bicycles are a way to break that link by providing access to healthcare, education and economic development opportunities." The bikes themselves, which cost 109 each, are purpose-built and culturally appropriate. World Bicycle Relief has partnered with RAPIDS, a USAID-funded consortium of six relief organizations, to provide the bikes to home-based, community volunteers caring for their neighbours affected by HIV/AIDS, including orphans and vulnerable children. These caregivers use the bicycles to increase their reach fourfold: while walking, they might cover two and a half miles per hour; by bicycle they are able to go 10 miles. te to their families and communities. World Bicycle Relief is supported by many bike trade companies. Download World Bicycle Relief's video about Zambia The Power of Bicycles to your video iPod or Apple TV via iTunes here.
This is perhaps the most played opening in Xiangqi today. Very complex. I have condensed and summarized some of the major or "orthodox" variations in this page. I used ppdc for edge cannon for chariot exchange because it is the hanyu pinyin abbreviation for this variation. The first 3 boards all deal with black's variations. The last board is the cumulation of all the three boards, so that you would have a better idea of the general picture. There are too many variations to be listed one by one and it is beyond my capabilities to present all of them. It would take away too much time from mahjong which I am sorely missing. Took me over a day to organize them. Enjoy.
The Resource Middle managers -- England -- Drama. 3 Items that share the Concept Middle managers -- England -- Drama. Context of Middle managers -- England -- Drama. Data Citation of the Concept Middle managers -- England -- Drama.
Before Obtaining a Reverse Mortgage, You Should First Decide Whether It's Practical/Affordable to Live at Home? Reverse Mortgage: Can You Live at Home? When deciding whether to obtain a reverse mortgage, there is one (if not many) important question that often gets overlooked: is it practical/affordable for the borrower(s) to continue living at home? In other words, before you can even think about reverse mortgaging your property, you must consider whether the property is even suitable for you. Actually, it's not enough to merely address current suitability; one must also consider future suitability. You are probably in excellent health now. At some point in the unforeseeable future, however, you probably won't be. While this possibility may seem very distant, you may regret not taking it into account if circumstances change after you receive your reverse mortgage. This issue is explored in detail by the National Council on Ageing (NCOA) Reverse Mortgage Booklet. According to NCOA, there are four factors that should be taken into consideration: changing needs, safety, ease of use, and isolation. The first three factors refer to the home itself. Is it uncluttered and well laid-out, from the standpoint of an elderly person (i.e. the future YOU). Is it handicap accessible, or can it at least be made handicap-accessible? Will the home require significant upkeep/repairs? The final factor isolation refers to location. Is the home conveniently located, from the standpoint of an elderly/handicapped person? Is it possible to get around and run errands without the use of a car? Is the location such that you would be worried about the prospect of becoming lonely? Next, you need to consider how you can obtain outside help if need be. Again, this might be a difficult notion to fathom in your current (healthy) state, but at least give it a thought. Will you be able to afford the cost of outside care, such as a home health aid? If not, perhaps you should account for this in your reverse mortgage budget. Otherwise, you need to ask yourself whether you can depend on "non-remunerative" care, whether from family, friends, charitable organizations, etc. What will you do when you can no longer care for yourself? Will you move into an independent/assisted living facility? If so, how will you pay for this, given that you may have depleted a significant portion of your home equity (from the reverse mortgage) in the mean time? Not only do you need to determine whether it's practical for you to remain in your home (for at least the 5-10 years that is required to make a reverse mortgage economical), but you must also determine whether it's affordable. Ask yourself how your reverse mortgage will impact your future finances, especially at the point at which you can no longer take care of yourself. If you spend all of the proceeds on the reverse mortgage now, what will you do after your health declines and you need to seek outside help? In short, it's essential that you be as financially far-sighted as possible when deciding whether to obtain a reverse mortgage today.
When you want wireless internet connections for your computer devices then Belkin WiFi router devices will best choice for you. Here are complete details for making some advance configurations for Belkin router devices. How to Configure PPTP and L2TP Functions for Tenda AC10U?
Are you a North Central College student needing tutoring for a specific subject? If so, we will try to match you with one of our top tutors who has made an A in the same course with the same professor at your university. If none of our tutors have attended your school, we will match you with a tutor who has mastered the content in the course of interest. We provide college students like you with the mentorship and academic support you need to help you improve your grades. Browse our list of top tutors who are students and graduates from North Central College and have an average GPA of 3.5 in their areas of tutoring specialization. Call us now or submit the tutor request form on the top right and start improving your grades.
Abu bin Dasha sat cross-legged in the center of the gorgeous carpet. The fabric walls of his tent were affixed in such a way as to catch the slightest waft of breeze, should one appear. The desert was capricious with breezes and everything else. He opened a carved sandalwood box and took out a pinch of tobacco gifted him by the British sea captain. As he packed the bowl of the bronze hookah, he surveyed his vast tent with complacency. The new Turkish carpet, the silken cushions from China, a delicious mint tea from India sweetened with Jamaican sugar. Allah is good, he thought. Then, wickedly, but he can always be better. Though a thoroughly modern city, the earliest recorded mention of Dubai is in 1095 in the Book of Geography by the Andalusian-Arab geographer Abu Abdullah al-Bakri. The Venetian pearl merchant Gaspero Balbi visited the area in 1580 and mentioned Dubai for its pearling industry. An interesting look into an ancient time and ancient race. Wonderfully told. Reminds me of Scheherazade and the Thousand and One Nights. Love this serving of history with a side of atmosphere. Well told. Clever title. ;) You always make me dig. I like that. Oh! A wee peek into history! Now I need to go look up more!
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Survey Concepts, Inc, dba SCI Development Services has been doing business in and around Metro Atlanta for over 13 years. In July of 2001, Survey Concepts opened a branch office in Gulf Shores, Al., which employs approximately 15 people, offering quality surveying to south Alabama. Our Atlanta firm employs roughly 35 people, which includes 8 field crews, and offers a wide variety of services, including Civil Engineering, all types of Land Surveying, Land Planning and Landscape Architecture. Shopping centers, parks, schools, single-family subdivisions, town homes, multi-family apartments, office parks and 150,000 s.f. +/- Warehouse/industrial sites. Our goal is to provide our clients with accurate surveying, and quality engineering in a timely manner. SCI is a member of the Gwinnett Chamber of Commerce and is actively involved with the Council for Quality Growth.
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Lisa Dawn Drogin is a Social Media Consultant and Specialist and Founder/Creative Director of Story of My Dress (thestoryofmydress.com, @storyofmydress). Her expertise spans Pinterest and social media marketing, community engagement, content creation, urban design and visual representation. As a Style Blogger and Social Media Influencer, she has collaborated on campaigns with Farfetch, University Village, Moorea Seal, Banana Republic, Uniqlo, Sorella Salon, Neiman Marcus, Bartell Drugs, and Pacific Place, as examples. Lisa was recently named by Seattle Refined as one of ten favorite Seattle Fashion Bloggers to follow on Instagram. Lisa holds dual Masters Degrees from the University of Michigan and grew up in the beautiful Pacific Northwest. An introductory workshop that will help you navigate building both a differentiated brand and product. Learn the key factors to starting, growing, and monetizing a successful blog. This event will bring together entrepreneurs in fashion to discuss their unique mission and how it inspires them to keep producing uniquely designed products.
The University of Tulsa Board of Trustees serves a vital role by outlining TU's long-term plans and providing leadership for one of the country's top institutions of learning. The board gains strength from its diversity with TU trustees that come from many different personal and professional backgrounds. The board is comprised of alumni as well as friends of the university who recognize TU's significance on the city, state and national level. Senior Finance Manager, Amazon.com
Two young Clarets goalkeepers have gone out on loan. Conor Mitchell has joined Scottish Premiership side St Johnstone for the season, while his Under 23s' colleague Aiden Stone has linked up with Lancaster City until January 1st. Both players signed new contracts at Burnley in the summer, and will now gain further senior experience. Mitchell, 22, was part of the first-team squad on their pre-season training camp in Cork, but has been allowed out to SPL side St Johnstone for the season, having started last season on loan at Chester City. The Northern Ireland Under 21 international has spent a few days training with St Johnstone and has now completed a move to McDiarmid Park.
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meningitis - a disease that is most common in childhood, when the infection (virus, bacteria, fungi) is most easily overcome the protective barriers, protecting the brain, provoke inflammation in the very near to his shell.Most often the disease occurs in children born with the pathology of the brain (hydrocephalus, cerebral palsy, brain damage in utero cytomegalovirus or Epstein-Barr virus), as well as premature.Kids who have a congenital defect of any of the units of immunity, also are much more likely to move meningitis.Symptoms of the disease in children are somewhat different (than adults). - from the patient, the bacterium which caused inflammation of the meninges. 1. The child becomes more sluggish, sleepy. 2. There may be vomiting, regardless of the meal. 4. In babies you may notice swelling of the large fontanelle (normally it is on a par with the bones of the skull). 5. A child receives an elongated posture in bed, often at the same time throws his head back. 6. react negatively to bright lights, loud noises, music. 8. There may be convulsions with impaired consciousness and stop breathing at any (even up to 38 degrees) body temperature. 9. If you raise a baby's armpits, he will draw the legs to his chest. 10. When meningococcal meningitis and some other body (primarily in the buttocks and legs), rash dark.It can be purple, brown, dark red.Its characteristic feature is that if you put pressure on spot transparent container (glass, jar) or glass, it does not pale.This means that the skin at this point saturated with blood. Rash having such characteristics becomes a tendency to merge with each other, as well as to the emergence in some areas of necrosis (necrosis) skin and underlying tissues. If you see some suspicious rash, especially on the back of higher body temperature, urgently call "ambulance."Even if it is - no meningitis symptoms in children of such a nature as rash - a reason for the hospitalization and treatment of infectious diseases hospital. What is laryngeal papillomatosis and what are its symptoms? About what can speak cough?
Donald Zook and the South Shore Conservatory Flute Symphony in Hingham, MA have commissioned John to compose a new work for flute choir in celebration of their 30th Anniversary Season in 2019! Murphy Music Press, a dynamic publishing house specializing in innovative works for winds has included two of John's works for wind ensemble in their catalog! Skronk and So Simple are now available for purchase and rental at Murphy Music Press. World premiere performance of John Frantzen's SKRONK for wind ensemble given by the Lawrence University Wind Ensemble under the direction of Dr. Andrew Mast. John with the UCSB Wind Ensemble in 2013. Conductor Paul Bambach and the University of California Santa Barbara Wind Ensemble will be performing the four movement CATALYST symphony on their upcoming 25th Anniversary concert on May 27, 2018! Dr. Richard Good and the Auburn University Symphonic Winds performed SKRONK for wind ensemble on their featured 2018 Auburn University Symphonic Honor Band Festival performance. The Concordia Band, under the direction of Dr. Peter Haberman, will be performing SKRONK for wind ensemble on their domestic tour across the Midwest! February 6-11, 2018. Dr. Dustin Barr rehearsing Catalyst with the CSUN Symphonic Winds. Dr. Dustin Barr and the California State University at Fullerton Symphonic Winds performed John's four movement Catalyst for wind ensemble on December 3, 2017. BEYOND A WILD DREAM on Performance Today Weekend! Broadcast during the second of hour of Performance Today's Weekend episode: September 16, 2017 "Josuha Bell and Sam Haywood play Spivey Hall". Fred Child, host. Broadcast during the second of hour of Performance Today's episode: September 14, 2017 "From Candlesticks to Stage Lights". Fred Child, host. John will have his new composition "Beyond a Wild Dream" premiered by The Quad City Symphony Orchestra on their 2014-2015 opening concert celebrating their 100th anniversary season. The premiere performance, under the direction of conductor Mark Russell Smith, will take place at the Adler Theater in Davenport at 8:00 p.m. on Saturday, Oct. 4. In addition there will be a matinee performance at Augustana College's Centennial Hall Auditorium at 2:00 p.m. on Sunday, Oct. 5. Other works featured will be Sergei Rachmaninoff's Piano Concerto No. 3, with Andre Watts, piano soloist and Antonin Dvorak's Symphony No. 9 "From the New World". Rose of Stambul recording now available at NAXOS.
a collaboration between organists and instrumentalists. In addition to the numerous performances in their home in southeast Texas, they have presented concerts nationwide in over 17 states. A short list of their many performance locations includes St. Patrick's Cathedral in NYC, The Basilica of Saints Peter and Paul in Maine, the Mayo Clinic Medical Center in Rochester, Minnesota, Washington Music Festival in Port Angeles, Washington, West Point Military Academy, and Myers Park United Methodist in Charlotte, North Carolina. They also presented a wildly successful headlining program for the L'Organo Series at the Piccolo Spoleto Festival in Charleston, South Carolina in May of 2015, where they performed the formal dedication concert for the new organ at The Citadel, and set a new record for the largest crowd for in the over thirty-year history of the series. In August of 2018, Deux Voix toured Denmark, Sweden, and Norway as a part of their Scandinavian Tour, and was a featured artist for the International Organ Festival in Bergen, Norway. In their mission to expand the world of trumpet and organ, Stephen and Justin are constantly adapting works from other genres and instrumentations, such as jazz, Broadway, opera, and current popular music. They also have premiered many new works written for trumpet and organ, including commissioned works by composers such as Mark Hayes and Craig Courtney.
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"MISRA" is a registered trademark of MIRA Ltd, held on behalf of the MISRA Consortium. Parts of this document are Copyright ©️ The Motor Industry Research Association, 1998, 1999. No endorsement by MISRA is claimed or implied for any product.
Jet Aviation is looking for BBJ Captains to be based in Burbank, CA. Must present a team effort approach with great interpersonal skills, attention to detail and strong organizational skills. Must be proactive, efficient, with the ability to seek out answers and resources as needed. Must be able to work flexible schedules, willing to travel worldwide extensively and without any restrictions. Must be able to handle the job responsibilities with integrity, discretion and sensitivity to confidential company and employee information.
This event will be held at ACMI and feature live entertainment from Australian musical comedy trio Tripod and three-piece jazz band 'Round Midnight. Please note: This event is open to summit ticket holders and invited guests only. It is not a public event. See below for the special Multiliteracies Sessions presented by VATE and ALEA. Share your passion and grow an audience on YouTube. Join the ACTF for a live Q&A discussion with the cast and creative team from one of Australia's groundbreaking new teen dramas. See below for the special games program at ACMI. For the first time, peak Victorian teaching associations the Australian Literacy Educators' Association (ALEA) and the Victorian Association for the Teaching of English (VATE) are collaborating with Australian Teachers of Media (ATOM) on a program for the Screen Futures Summit. These sessions will focus on the interplay between Media, Literacy and English, and how this can be realised in classroom practice. Issues, ideas and understandings will be discussed and debated by key Literacy and English educators. Keynote speakers, informative panels, and a range of practical workshops pertaining to primary and secondary English and Literacy, have been carefully planned to engage discussion around using language to both create and interpret texts in new and original ways. These sessions have been designed to inspire, support and develop teachers' understanding and skills in order to include game design in their Digital Technologies classes. Game design, game play and learning from games provide a range of engaging means for students to learn computational and design thinking, as well as developing game narratives. Keynote speakers, masterclasses and a range of practical workshops pertaining to primary and secondary classrooms are planned to be accessible to teachers of all skill levels. Session is programmed exclusively. A noted speaker of international or national repute, speaking on a topic that has significant cultural, theoretical or practical implications for the production and consumption of media and the screen. A moderated presentation and discussion between four or five industry practitioners, education leaders or experts in a field. Topics will be linked to the themes of the conference and those developed by the preceding keynote. Relevant resources will be made available online. An opportunity to focus on a topic in greater depth. An expert will share insights and experiences from working in media education or the creative media industries. Relevant resources will be made available online. A presenter who delivers an academic paper, case study or research findings to a smaller audience. May include discussion/interaction with/between delegates. A skills development session delivered by expert teachers, industry practitioners or education service providers. Includes hands-on training and supply of practical resources that can be used in the classroom. Relevant resources will be made available on the day. Screening followed by a Q&A session. May include films, series, other media productions, education-based media initiatives or resources.
Ayhan, F. & Konopka, G., Mar 8 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 89, p. 57-64 8 p. Berto, S., Wang, G. Z., Germi, J., Lega, B. C. & Konopka, G., May 1 2018, In : Cerebral cortex (New York, N.Y. : 1991). 28, 5, p. 16 p. Araujo, D. J., Toriumi, K., Escamilla, C. O., Kulkarni, A., Anderson, A. G., Harper, M., Usui, N., Ellegood, J., Lerch, J. P., Birnbaum, S. G., Tucker, H. O., Powell, C. M. & Konopka, G., Nov 8 2017, In : Journal of Neuroscience. 37, 45, p. 10917-10931 15
Stop by your nearby Firestone Complete Auto Care for the best 2017 Audi A4 tires at a great price. Browse our wide catalog of 2017 A4 tires and compare by tire price, size, type, and brand. Whether you're looking for tires built for speed, versatility, or fuel-efficiency, you'll find the right ones for your vehicle and your budget. Shop online and then schedule a convenient appointment with one of our ASE-certified technicians today! When you need new tires, we're ready. We're open late and on weekends!
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Hart & David assists those facing work-related injuries in obtaining the compensation they deserve. In some cases, this may involve an injury resulting from working in an office. While not as obviously perilous as some other occupations, office work does present its own unique risks to the health and wellbeing of employees. We represent those who are victims of theses risks and need compensation for their injuries. Workers' compensation laws are designed to protect employees in the event that they suffer an injury while on the job. This includes office workers, and we will fight on your behalf to help you secure the benefits you deserve for your office work injury. Hart & David has proven experience and skill in these cases, so we can provide the help you need. Most of these take time to develop, and they can result from poor equipment, less than ideal workstations, or simple negligence on the part of others in the work environment. Failure to keep a workplace clean or expecting employees to come in when they are ill can lead to the spread of disease, for example. Sitting in a chair all day that isn't designed for musculoskeletal support can lead to back and muscle strain over time. It's important to take these seriously since they can lead to debilitating repeated stress injuries. These injuries can affect your ability to work productively (or at all), especially if they are ignored long enough. Eventually, they will result in medical costs that you wouldn't have had to pay otherwise. Your employer is responsible for maintaining a safe, healthy work environment. In the event that they don't, or when they overwork their employees, they become responsible for the injuries and illnesses that result. Workers' compensation law is designed to uphold the rights of employees who have been injured as a result of performing job-related tasks, including office work. If you have suffered an injury as a result of working in an office setting, Hart & David is here to defend your rights and help you obtain the compensation you deserve. Workers' compensation benefits include medical expenses, rehabilitation and physical therapy costs, disability, and lost income. Our attorneys can assess your claim and determine the best course to take. Keep in mind that your employer or their insurance company will try to downplay your injury or prove that your medical treatment isn't necessary. No matter how minor your injury may seem, contact the attorneys at Hart & David for the legal help you need to get the workers' compensation benefits you deserve.
The NCCER blue wallet card is given to anyone who completes Core Curriculum level or any other full level of craft training through an Accredited Training Sponsor. A blue wallet card is also given to anyone who successfully completes an NCCER Written Assessment (knowledge Verified) or Performance Verification (Performance Verified). The card number located on the front of the card can be used search and verify all completions and certifications in the NCCER Registry System. The NCCER silver wallet card is given to anyone who has earned a Certified Plus credential. To become Certified Plus, an individual must complete both the written assessment (Knowledge Verified) and performance (Performance Verified) components of NCCER's National Craft Assessment and Certification Program (NCACP). The NCCER gold wallet card is given to anyone who successfully completes NCCER Mobile Crane Operator, Rigger and/or Signal Person, or Tower Crane Certification Program. In order to earn "Certified" through one of these programs, the individual must complete both the written assessment and practical exam components of these NCCER certification programs. The NCCER wallet card itself is not proof of training credentials or certifications. All credentials should be verified by searching an individual's record in NCCER's Registry System using their NCCER wallet card number. Go to registry.nccer.org and select the Online Verification feature for verification of training credentials and/or certification.
They met again the next evening at a dinner party. By then, Byron had learned that Stendhal had been a secretary to Napoleon, Byron, fascinated by Napoleon, became more interested in Stendhal and friendlier. They met almost every evening in the following weeks, and Byron questioned the Frenchman about Napoleon. "I remember," Stendhal recalled afterward, "that in his moments of genius, Lord Byron admired Napoleon. In his ordinary moments, when Lord Byron believed himself a great lord, he tried to ridicule the exile of St. Helena, Lord Byron was envious of the brilliant aspects of Napoleon's character; his sublime words annoyed him; we put him quite out of humor by recalling the famous proclamation to the army in Egypt: 'Soldiers, remember that from the height of these pyramids 40 centuries look down upon you.' Lord Byron could have pardoned Napoleon more easily if he had had a little of the colorlessness of Washington. Amusingly, it was not at all the despotic and odious part of Napoleon's character which displeased the English peer." During several other conversations, Stendhal told Byron of some of the emperor's shortcomings that he had personally observed. At the height of the invasion of Russia, for example, Napoleon had seemed absentminded and apathetic, signing many military orders with an imaginary name instead of his own. Sitting on a hill during the Battle of Borodino, learning that his closest generals had been killed, he had been strangely cold, dismissing the couriers with "Very well, run along there." In the winter retreat from Moscow, the emperor had insisted on riding his white horse instead of going on foot, even though the ground was too slippery for his mount. As he got to know Byron better, Stendhal had a great ambivalence about the poet. Whenever Byron appeared at a gathering, Stendhal said, "there was the finest conversation which I have ever known in my life; a volcano of new ideas and generous sentiments." Stendhal also found Byron "the most amiable monster that I have ever seen; in poetry, in literary discussions, he is simple as a child; he is the opposite of an academician." But Stendhal detected two sides to Byron: "When that singular man was elated and spoke with enthusiasm, his sentiments were noble, grand, generous, and in a word, did justice to his genius. But in the prosaic moments of life, the sentiments of the poet seemed to me very ordinary. There was much petty vanity, a continual and puerile fear of appearing ridiculous, and sometimes, if I dare say it, that hypocrisy which the English call cant."
The 2017 Saint-Peray Cuvee Prestige is also brilliant, with buttered citrus, peach, tangerine, and some salty characteristics all just about soaring from the glass. Medium to full-bodied, pure, elegant and layered, it shows the vintage's richer, riper style yet has freshness, purity, and focus. This cuvee is 80% Marsanne and 20% Roussanne, and spent ten months in barrel.
I was looking for a friend of mines site about his documentary on a young soldier in Iraq called 'The World on Fire' and I found Sarah McLachlan's World on Fire site.Boy, I was really impressed.What a great thing to do to point out the comparative realities of life on this planet, and how we, I take things for granted. The world has so many people in it, and here I am sitting at a new laptop, posting through broadband my silly thought about the world through my eyes.I am almost broke and looking for new work, thinking I am a poor man in this culture, while my belly is full, I have clean water to drive, have access to health care, my electricity and phone bills are paid for and when I was walking down the street this morning I did not have to fear being blown up, shot dead on the street by armed thugs, or worry about whether the air was filled with plutonium. That is my mini gratitude list for the day. Eric Barrier (Eric B.) and William Griffin (Rakim), were a hip-hop duo known as Eric B. & Rakim. The duo popularized the jazz-influenced hip-hop of the late 1980s. Despite spawning no major chart hits, the pair is generally considered to be one of the most influential and groundbreaking groups in the history of hip hop, due to both Eric B.'s jazzy production and Rakim's revolutionary rhyming style, which was smooth, seemingly effortless, and used remarkably complex rhyming schemes involving internal rhymes and sophisticated metaphors. It is the general consensus that almost all modern MCs have been influenced in some way by Rakim's rhyming technique. Eric B.'s use of a James Brown sample in "I Know You Got Soul" introduced the godfather period of extensive use of old R&B and soul music as background music for hip hop songs.
Caroline and Robin Weir's book is the biggest selling book on ICES that has ever been published. It is universally regarded as the bible on the subject. Now for the first time since then the book is being issued in a paperback edition.
Guernsey is one of three Crown Dependencies of the United Kingdom and is located in the English Channel approximately 30 miles off the French coast. Although the UK Government is responsible for the conduct of external relations and defence, the "Bailiwick" of Guernsey is self-governing and has its own legislative assembly (the States), legal system and courts (although the ultimate court of appeal is the English Privy Council). The virtual absence of party politics encourages a high degree of consensus and contributes to political and economic stability. In combination with low or non-existent taxes on company income and a lack of other taxes (including capital gains tax, estate and inheritance taxes) the island has enjoyed a sustained period of growth and prosperity and an offshore financial services industry has been allowed to flourish; financial services now account for over half of the island's total income. Offshore banking, trusts and fiduciary services and investment funds are the main sectors of interest for individuals seeking offshore wealth management and asset protection solutions, although foundations, an image rights register and an aircraft registry have been added in the past few years. These are outlined in more detail later in this feature. Corporate financial services have also become an important component of Guernsey's finance industry and the island is home to more entities listed on the London Stock Exchange than any other jurisdiction, excluding the UK. Guernsey's financial services industry is regulated by an independent regulator, the Guernsey Financial Services Commission (GFSC). The GFSC is responsible for regulating the banking, investment fund, insurance and fiduciary sectors and has wide-ranging powers of enforcement, although it is not a prosecuting authority and must refer criminal matters to the appropriate law enforcement bodies. In June 2013, the GFSC increased its capacity to undertake professional and efficient enforcement action with the creation of the post of Director of Enforcement, and the establishment of a dedicated Enforcement Division. This is designed to further enhance the Commission's ability to undertake proportionate and efficient enforcement action. "The Commission does not seek to be an enforcement-led regulator but, in the same way that the police require powers of arrest and a capability to make arrests, the Commission requires an effective enforcement capability if it is to be able to deter wrongdoing and poor practice thereby keeping Guernsey's financial sector safe," said William Mason, the Commission's Acting Director General. Traditionally, Guernsey's banks and trusts have been used by residents of the United Kingdom due to a combination of geographic proximity and familiarity; despite its closeness to France, the Channel Islands are, to all intents and purposes, British. In recent times, successive tightenings of anti-tax avoidance legislation in the UK have reduced the opportunities for Britons to manage their wealth from an offshore base. However, Guernsey has benefited enormously from rising levels of wealth in emerging markets, and Asia in particular has become one of the world's largest wealth management markets. China especially has become an important territory for Guernsey, and the Government, in tandem with the island's finance industry promotional agency Guernsey Finance, has worked hard to cultivate good relations with the Chinese authorities. For example, in April 2013, the Chinese ambassador to the UK, Liu Xiaoming pledged to work with Guernsey towards a number of initiatives to boost Guernsey's access to the Chinese market, in particular in the financial services sphere. "In addition, Guernsey can provide a gateway through which structures, including funds, can be established for investing out of and into China," Le Poidevin added. "Chinese clients might use a Guernsey vehicle for accessing European capital markets or alternatively, managers and investors globally might use funds domiciled in Guernsey for investing into China. There is still much work to do but as long as we play our part then the ambassador has agreed to assist us in our work." Guernsey Finance established a representative office in Shanghai in 2007 and since then a number of senior-level visits have been hosted by both territories. The first bank to be established on the Island was the Guernsey Savings Bank, which was founded in 1822, and until the 1960s, when merchant banks began to establish operations on the island, banking in Guernsey was purely domestic and largely conducted by the major British high street clearing banks. Today however, Guernsey's banking sector is a major pillar of its offshore financial services industry, and the island is home to subsidiaries of international banking groups with head offices in Switzerland, Europe, the United States and the United Kingdom, among other places. The sector provides products ranging from retail banking and savings, international wealth management through to institutional business and specialist lending. It also services the other financial sectors on the island, such as trusts, insurance and investment funds. Originally, banks coming to Guernsey set up fully-staffed local branch offices or subsidiaries, but in recent years, as in many other IOFCs, in response to shortage of resources, the administered unit has become more popular. Under this scheme, an established Guernsey bank provides services for an incoming bank, which therefore does not need to open its own office or recruit staff. However, the GFSC applies the same standards of supervision to an administered bank as to an established bank. At the time of writing, 31 banks were licensed in Guernsey. These are listed in the table below. As of the end of December 2013 deposits in Guernsey banks stood at GBP83.7bn. As mentioned above, trust management, particularly for wealthy UK individuals, was the mainstay of island's finance industry. However, even though the UK market for trust services has shrunk, Guernsey's trust sector has continued to grow as a result of a more international client base. The Trusts Law 1989 (updated in 2007) provides a modern statutory basis for trust management activity in Guernsey, and the island has a very well-developed legal and financial infrastructure for trust management; the highly sophisticated professional services which support the trust sector include lawyers, accountants, investment managers and stockbrokers. Until quite recently, Guernsey's trusts industry had not been subject to any formal system of supervision. This all changed on April 1, 2001, when the Regulation of Fiduciaries and Administration Businesses (Bailiwick of Guernsey) Bill 2000, otherwise known as the Fiduciaries Law, came into effect. The law contains a 'four eyes' rule, standards for capital adequacy and compulsory indemnity insurance, and the unlicensed offer or provision of fiduciary services is a criminal offence. A full licence is required by any company, wherever registered, providing fiduciary services in the Bailiwick and by Guernsey-registered companies providing fiduciary services anywhere in the world and individuals, acting as directors or trustees by way of business, need a personal licence. Prudential rules have also been imposed, and clients' funds need to be segregated from other trust assets. New accounting safeguards were also installed by the legislation. At the time of writing, 802 persons were listed by the GFSC as holding a fiduciary licence under the Fiduciaries Law. Together, they held between GBP200 and GBP300bn worth of assets in trust. The Guernsey Registry began accepting applications for the formation of foundations on January 9, 2013, following approval of the legislation by the UK Privy Council. A foundation is an incorporated, self-owning, legal entity which, although having much in common with a trust, has a distinct legal personality, something that is more commonly associated with companies. A foundation has similar features to a trust in that it has a founder who is similar to a settlor, beneficiaries who have similar rights to those of a discretionary trust, and a foundation instrument and rules which are similar to a trust deed. Foundations are commonly used for wealth management, and residents of jurisdictions in the Middle and Far East are more familiar with foundations than with trusts, which tend not to exist in their legal systems. The Foundations Law therefore allows Guernsey's fiduciary professionals to consider the use of a foundation as well as a trust when adopting wealth structures for their clients. As Le Poidevin observes: "Foundations may be particularly attractive to those based in civil law jurisdictions in Europe and further afield in the emerging markets of China, Russia and Latin America where the foundation concept is more familiar." Foundations business in Guernsey is starting to grow, according to Guernsey Finance. Since the introduction of the Guernsey Foundations Law at the beginning of 2013, 16 foundations have been registered in the Island. Collas Crill specialist fiduciary lawyer Angela Calnan told an audience at an Institute of Chartered Secretaries and Administrators presentation in January 2014 that her firm had been responsible for a quarter of those registered. "By being able to offer foundations, Guernsey now has an innovative tool in the Island's wealth and succession planning offering and this has attracted a wider client base to Guernsey," said Calnan. "We are now seeing a significant increase in interest in Guernsey from clients in civil law jurisdictions, who are uncomfortable with the idea of a trust and the perceived loss of control associated with it, and who seek a greater degree of influence over the administration of their wealth or require more bespoke wealth-planning solutions." Guernsey plays host to an extensive array of businesses involved with investment funds. These include investment advisers, stockbrokers and more than fifty fund managers, custodians and administrators, who combine to offer a range of products and services for both retail and institutional investors. The international nature of Guernsey's market place for investment funds is illustrated by the fact that Guernsey funds are now promoted in more than 55 financial centres. Guernsey is particularly adept when it comes to alternative investment funds, and the island's fund professionals have come to specialise in areas such as funds of hedge funds, private equity and property funds. Increasingly, the more obscure types of alternative investment fund are basing themselves in Guernsey, including those investing in fines wines, fine art and timber. A thriving investment services industry has also grown up around the investment funds sector, including subsidiaries of large multinational houses as well as independent boutiques. In combination these firms deliver a wide range of asset management and stockbroking services to both private and corporate clients. Guernsey legislation permits the formation of both open-ended and closed-ended funds, and there are various sub-classes of funds aimed at different segments of the investment funds market. Open ended funds may be established as Class A, B or Q funds and are constituted as companies, protected cell companies or unit trusts. Class A schemes are those which meet the GFSC's Collective Investment Schemes Rules 2002 and are therefore eligible for recognition by the UK financial services regulator as eligible for sale to the public in the UK. Class B schemes incorporate a measure of flexibility and range from the retail fund aimed at the "general public" via institutional funds to the strictly private fund established solely as a vehicle for investment by a single institution. Their investment objectives and risk profiles are similarly wide-ranging. The Class Q Rules seek to provide a clear and concise set of requirements for the operation of professional investor funds and have been designed to encourage innovation. A Qualifying Investor Fund (QIF) regime was introduced following consultation with the financial industry in 2004. Under a streamlined application process, the Commission undertakes to grant fund approval within three working days provided that an appropriately licensed Guernsey applicant has certified that: the fund will be restricted to professional, experienced and knowledgeable investors; the applicant has conducted due diligence on the promoter and associated parties and has found them to be fit and proper; and the applicant is satisfied as to the fund's economic rationale and the disclosure of any risks associated with the investment vehicle. The GFSC approved 30 new investment funds during the fourth quarter of 2013. Throughout the whole year a total of 103 new funds were approved. The net asset value of funds under management and administration has seen five-year growth of 33% and stood at GBP266bn at the end of December 2013, although this was just under GBP11bn lower than at the same point in 2012. She added: "During 2013 we saw a notable increase in the number of new funds being approved for domiciling or servicing in Guernsey. Indeed, it is something of a vote of confidence in Guernsey's approach to the Alternative Investment Fund Managers Directive (AIFMD) that a significant number were approved after the start of its implementation in Europe." Guernsey's own opt-in AIFMD equivalent regime came into effect from January 2, 2014. This is the second strand of a "dual regime" where the other parallel regime is the existing regulatory framework for managers and investors not requiring an AIFMD fund, including those using EU national private placement regimes, and those marketing to non-EU investors. In July 2013, the GFSC signed bilateral cooperation agreements with 27 securities regulators from the EU and the wider European Economic Area (EEA), including the United Kingdom, France and Germany. The cooperation agreements provide a set of arrangements for the on-going supervision of alternative investment funds, including hedge funds, private equity and real estate funds. They are applicable from July 22, 2013, which is the deadline for EU countries to transpose the provisions of the AIFMD into national law. Guernsey's dual regime is expected to appeal to fund managers all over the world, particularly in China, the Middle East and the United States, three areas where Guernsey Finance has been concentrating its marketing efforts in recent years. "Knowledge in the US about AIFMD is variable but it is important for managers to know how it may impact them and what options they have at their disposal," noted Le Poidevin ahead of a 2013 promotional trip to the US designed to showcase Guernsey's wealth management and fund management expertise to US fund managers. She added: "We will be highlighting that Guernsey's position of being close to Europe but not in the EU and our intention to introduce a dual regime, which will allow us to continue to distribute our funds to both EU and non-EU countries, means that we will be uniquely positioned as an international funds center." The world's first image rights legislation, The Image Rights (Bailiwick of Guernsey) Ordinance, 2012, entered into force on December 3, 2012, following approval by the States, on November 28, 2012. The legislation positions Guernsey as the first jurisdiction to have a legislative framework to register an image, enabling effective management and control of the commercial use of a person's identity, images associated with that person, including distinctive characteristics, such as signature, voice, mannerisms and gestures. The ground-breaking law will create an image rights register enabling legal recognition of a "registered personality" (i.e. the exclusive rights to the images associated with or registered against the personality). Once registered, the image right, as an identifiable asset, can be placed within a Guernsey structure, adding flexibility to allow image rights income to be channeled into a wealth management structure such as a trust, or for instance, a partnership structure to overcome complex asset ownership arrangements. By establishing a legal structure to house one's image offshore, significant tax advantages can be unlocked. The new legislation will enhance the argument that income derived from image rights should be taxable in the jurisdiction in which they are registered. The development of Guernsey's legislation comes after years of uncertainty surrounding the tax treatment of endorsements and sponsorship deals received by sporting personalities, musicians and media personalities. For example, the UK tax authority, HMRC, has sought to receive a share of sports personalities' image rights income when they appear on UK soil, regardless of where their image rights are said to be structured. In 2013, Guernsey launched an aircraft registry, a development that Guernsey Finance described as adding "yet another service to the menu of options which we can offer our global client base." "Guernsey has many fiduciary services providers with high net worth clients who own aircraft and now they can take advantage of the modern legislation offered by our aircraft registry," Le Poidevin explained. "Indeed, it is expected to be particularly attractive to clients from emerging markets such as the Middle East, Russia, and Asia where personal luxury aircraft ownership is very popular, and it may encourage them to consider using Guernsey for their wider wealth management needs." Earlier it had been proposed that fellow Channel Island Jersey join forces with Guernsey to establish a combined registry. However, negotiators agreed that the project would not have been mutually beneficial, partially due to differences in the islands' tax regimes. Guernsey is among the top-tier of jurisdictions when it comes to regulation, tax transparency and administrative cooperation, and is easily one of the 'cleanest' financial centres out there, offshore or otherwise, having signed up, or committed to, several information exchange initiatives in recent times. In December 2013, Guernsey and Jersey signed Foreign Account Tax Compliance Act (FATCA) agreements with the United States on December 13, 2013. This followed the signing of an inter-governmental agreement with the UK to improve the automatic exchange of tax information between the jurisdictions in a FACTA-style agreement in October 2013. In November 2013, the OECD singled out Guernsey for praise after it signed its 50th tax information exchange agreement. Commenting on this achievement, Pascal Saint-Amans, the OECD's Head of Global Tax Policy, observed that: "Guernsey has been one of the most active jurisdictions promoting transparency in practice. Guernsey started negotiation of agreements prior to 2009, paving the way for many other jurisdictions. The number of TIEAs signed so far seriously enhances Guernsey's reputation as a responsible and transparent financial center, as recognized by the Global Forum peer review." Additionally, Guernsey has signed up to measures equivalent to the EU Savings Tax Directive, and in 2011, Guernsey adopted automatic exchange of information under these measures. Guernsey has also committed to joining the OECD Multilateral Convention on Mutual Administrative Assistance in Tax Matters. The Guernsey authorities, including the GFSC are committed to meeting established international standards on anti-money laundering and combating the financing of terrorism (AML/CFT), and the jurisdiction has received praise from international bodies on the strength of its AML/CFT regime; both the October 2003 and the January 2011 International Monetary Fund evaluations of the AML/CFT framework of Guernsey concluded that the Bailiwick has a high level of compliance with the standards set by the Financial Action Task Force (FATF). Non-Regulated Financial Services Businesses: The Registration of Non-Regulated Financial Services Businesses (Bailiwick of Guernsey) Law, 2008 came into force on 30 July 2008 requiring registration with the Commission and compliance with the Criminal Justice (Proceeds of Crime) (Financial Services Businesses) (Baiiwick of Guernsey) Regulations, 2007 and the Handbook for Financial Services Businesses on Countering Financial Crime and Terrorist Financing. Prescribed Businesses (including Legal Professionals, Accountants and Estate Agents): The Criminal Justice (Proceeds of Crime) (Legal Professionals, Accountants and Estate Agents) (Bailiwick of Guernsey) Regulations, 2008 came into force on 8 September 2008 requiring registration with the Commission and compliance with the regulations and the Handbook for Legal Professionals, Accountants and Estate Agents on Countering Financial Crime and Terrorist Financing. Money Services Provides: The Criminal Justice (Proceeds of Crime) (Financial Services Business) (Bailiwick of Guernsey) (Amendment) Regulations, 2008 came into force on 8 September 2008 requiring registration with the Commission. According to the GFSC, the framework, including the registration, has no effect on the conduct of business of a registered business except for the carrying out of AML/CFT measures. A great deal of useful information on Guernsey's offshore business, banking, investment and tax regimes is available in the Guernsey Knowledge Base of .
The Deseret News recently revealed a list of the 62 best companies to work for in Utah. Once again, Castle & Cooke Mortgage (NMLS# 1251) landed near the top of the list of local companies at number 15, the highest-ranked mortgage company on the list. The list ranks local, Utah-based companies based on data from Glassdoor.com. Contenders are chosen based on their overall ranking, number of reviews, and reviewers' likelihood of recommending the company to a friend. As of June 20, 2017, Castle & Cooke Mortgage boasts a Glassdoor rating of 4.6/5, with 94% of reviewers indicating they would recommend the company to a friend. Castle & Cooke Mortgage is hiring!
Matthew 1:16 and Jacob the father of Joseph, the husband of Mary, of whom was born Jesus, who is called Christ. and Jacob the father of Joseph, the husband of Mary, and Mary was the mother of Jesus who is called the Messiah. Jacob was the father of Joseph, the husband of Mary. Mary gave birth to Jesus, who is called the Messiah. and Jacob the father of Joseph, the husband of Mary, of whom was born Jesus, who is called Christ. And Jacob begat Joseph, the husband of Mary, of whom was born Jesus, the One being called Christ. and Jacob fathered Joseph the husband of Mary, who gave birth to Jesus who is called the Christ. and Jacob fathered Joseph the husband of Mary, who gave birth to Jesus who is called the Messiah. Jacob fathered Joseph, the husband of Mary, who was the mother of Jesus, who is called the Messiah. and Jacob the father of Joseph, the husband of Mary, by whom Jesus was born, who is called Christ. and Jacob the father of Joseph, the husband of Mary, from whom was born Jesus, who is called the Messiah. Yaqob begot Yoseph the guardian of Maryam, her from whom was begotten Yeshua, who is called The Messiah. [Jacob] was the father of [Joseph], who was the husband of Mary. Mary was the mother of [Jesus], who is called Christ. and to Jacob was born Joseph the husband of Mary, by whom was born Jesus, who is called Christ. Jacob begat Joseph the husband of Mary, of whom was born Jesus, who is called Christ. And Jacob begot Joseph the husband of Mary, of whom was born Jesus, who is called Christ. and Jacob begat Joseph, the husband of Mary, of whom was born Jesus, who is called Christ. and Jacob of Joseph the husband of Mary, who was the mother of JESUS who is called CHRIST. Jacob became the father of Joseph, the husband of Mary, from whom was born Jesus, who is called Christ. and Jacob begat Joseph, the husband of Mary, of whom was begotten Jesus, who is named Christ. Then He admonished the disciples not to tell anyone that He was the Christ. So when the crowd had assembled, Pilate asked them, "Which one do you want me to release to you: Barabbas, or Jesus who is called Christ?" "What then should I do with Jesus who is called Christ?" Pilate asked. They all answered, "Crucify Him!" to a virgin pledged in marriage to a man named Joseph, who was of the house of David. And the virgin's name was Mary. Today in the City of David a Savior has been born to you. He is Christ the Lord! And when they were departed, behold, the angel of the Lord appeareth to Joseph in a dream, saying, Arise, and take the young child and his mother, and flee into Egypt, and be thou there until I bring thee word: for Herod will seek the young child to destroy him. Strong's Greek 2384: Of Hebrew origin; Jacob, the progenitor of the Israelites. Strong's Greek 2501: Joseph, a proper name. Of Hebrew origin; Joseph, the name of seven Israelites. Strong's Greek 3137: Or Mariam of Hebrew origin; Maria or Mariam, the name of six Christian females. Verse 16. - And Jacob begat Joseph, the husband of Mary. St. Luke calls Joseph "the son of Heli." There are two ways in which these differing statements may be made to accord. The two sons of Matthan were Jacob the elder, and Heli the younger. It may be that Mary was the only child of Jacob, and Joseph the son of Heli. Then by marriage with his cousin, Joseph would become Jacob's son as well as Heli's. Or it may be that Jacob died without children, and Heli, marrying his widow according to the Jewish usage, became by her the father of Joseph, who hence would be called Jacob's son, that the elder brother's line might not die out. The points noticed above in respect of these varying pedigrees seem to be all those on which anything needs to be said with the view of comparing them. Their variety stands as a constant evidence of the independence of the two evangelists. Had either of them been conscious of the existence of the other's work. it is inconceivable that he would have made no effort to adjust the pedigree, for which he would possess means now lost for ever. They both design to give us the descent of Joseph from David, this being what a Sew would most regard. The descent of Mary from David is nowhere definitely mentioned in the Gospels, but that Jesus was sprung from David on the mother's side too we are warranted in concluding from the words of the angel to Mary (Luke 1:82), "his father David" (cf. also Delitzsch, 'Hess. Proph.,' 17). But though we ought not to spend vain labour in attempting to reconcile these two genealogies of Joseph, we can see, from what we know of Jewish customs, grounds enough for understanding how these variations came to exist. The same Jew, we find, was often known under two names; of this we have several examples in the lists of the twelve apostles. It is possible, therefore, that in these two pedigrees there may have been more points of union than we are able to detect. Then the rule, before alluded to, by which a man took the childless widow of his deceased brother for his wife and raised seed unto his brother, may also have led to much confusion of names, which we have now no means of unravelling. The evangelists drew each his own list from some authentic source, accessible to others beside themselves, and the record of which could be verified when the Gospels were set forth. This should satisfy us that those we have received were held by the Jews soon after Christ's time to be truthful records, and that each established from a Jewish point of view the descent of the putative father of Jesus from King David. Of whom was born Jesus. This name, which, through Jeshua, is the Greek form of Joshua (for which, indeed, it stands in the Authorized Version of Acts 7:45 and Hebrews 4:8), signifies "Jehovah is help," and was not an uncommon name among the Jews, though given with marked significance at this time (see ver. 21). We find, according to the best texts, that in Luke 3:29 this name occurs in the pedigree of Joseph (where the Authorized Version has Jose), and the Revised Version has adopted that reading. (Of the way in which the name was augmented when given to the famous successor of Moses, see Numbers 13:16.) Who is called Christ. The evangelist here alludes merely to the well-known fact that Jesus was called by this name. The significance of the word, which is a translation of the Hebrew Messiah, is "anointed," and in the Old Testament it is given to priests (as Leviticus 4:3, 5, 16), to a king appointed by Jehovah (1 Samuel 24:6, 10; 2 Samuel 19:21), also to King Cyrus (Isaiah 45:1), and to some unnamed representative of Jehovah (1 Samuel 2:10). It was subsequently applied to Jesus both in the Greek form and in the Hebrew (John 1:41; John 4:25). It must, however, be noticed ( vide Bishop Westcott, Add. Note on 1 John 5:1) that it was not a characteristic title of the promised Saviour in the Old Testament, and was not even specifically applied to him, unless, perhaps, in Daniel 9:25, 26 - a passage of which the interpretation is very doubtful. 1:1-17 Concerning this genealogy of our Saviour, observe the chief intention. It is not a needless genealogy. It is not a vain-glorious one, as those of great men often are. It proves that our Lord Jesus is of the nation and family out of which the Messiah was to arise. The promise of the blessing was made to Abraham and his seed; of the dominion, to David and his seed. It was promised to Abraham that Christ should descend from him, Ge 12:3; 22:18; and to David that he should descend from him, 2Sa 7:12; Ps 89:3, etc.; 132:11; and, therefore, unless Jesus is a son of David, and a son of Abraham, he is not the Messiah. Now this is here proved from well-known records. When the Son of God was pleased to take our nature, he came near to us, in our fallen, wretched condition; but he was perfectly free from sin: and while we read the names in his genealogy, we should not forget how low the Lord of glory stooped to save the human race.
It is back to school here for the teenagers- with all the teenage angst that goes with it. I can't believe how expensive school shoes are and then they all "have to have" t-bars which are the most expensive- ridiculously expensive and which actually have cardboard in the soles- so one incident of getting wet and the shoes warp. But yep every girl has to have these and parents get harassed to get them. So not much getting done on the work front. NETHERLANDS:I have organised a workshop in the Netherlands at the Quilters Palette in The Hague on Sunday 24 February 2008. Dijanne is een (in Nederland geboren) Textiel/Quilt Kunstenares die sinds haar 10e in de Otway Ranges van Victoria Australie woont. , Ze creeert, onderwijst, schrijft en maakt originele (Quilt) Art. Ook verft ze haar eigen stoffen. Ze heeft diverse internationale Quilttentoonstellingen gecureerd waaronder een prachtige tentoonstelling in Panorama Mesdag in 2006. Wij zijn dan ook erg blij dat Dijanne speciaal voor het QuiltersPalet tijd heeft gevonden in haar drukke schema om een workshop Tifaifai te geven. Deze techniek is door Dijanne ook beschreven in haar boek Tifaifai Renaissance, gepubliceerd door Pride Publishing. Bij deze workshop ga je aan de slag met technieken die terug te vinden zijn in de prachtige Polynesische quilts. (ook bekend als Tahitiaans (echo) applicatiewerk) Wij zullen daarbij echter gebruik maken van moderne, hedendaagse inspiratiebronnen. Deelnemers kunnen hun Quilt maken aan de hand de door Dijanne meegebrachte ontwerpen maar zij zal ook laten zien hoe simpel het is om een eigen ontwerp te tekenen en uit te voeren. De keus is aan jou! De ontwerpen zullen simpel en niet al te groot zijn. Zij kunnen een opzichzelfstaande kleine Quilt vormen. Maar kunnen eventueel ook gebruikt worden als blokken waaruit je een grotere Quilt kunt samenstellen. Er zal gebruik worden gemaakt van een eenvoudig, uit 2 kleuren bestaand, palet met eventueel een 3e kleur als highlight of contrast. Het doel is een Quilt te maken die er echt "uitspringt". Level: voor iedereen die ervaring heeft op de naaimachine. Uiteraard moet je zorgen dat je naaimachine op de dag van de workshop in topconditie is. FRANCE: It also looks as if we have managed to get a space for a workshop just outside of Paris at Crecy-la-Chapelle. There is a patchwork atelier and the space is available for use on the16-17 February 2008. If you are interested in any of these workshops please email me and I will send you further information. I have been dyeing red red fabric- somehow good reds with a lot of depth of colour have eluded me this past year- not sure why, perhaps our water has more chlorine in it than normal, which would not be surprising given the dry conditions until recently. All my hand dyed fabrics are for sale if anyone is interested ( 35 US for a metre inclusive of postage). I have also made up some Zenobia dolls ready for hand stitching- what i thought was a reasonably happy face looks rather doleful to me- of course she will change with stitching and headdress- so we'll see. I am flying to Europe on the 4th of February to be with my aunt ( well she is more like a sister- our age difference is not so great) as my uncle's condition is all downhill. I am forever grateful that we went to Italy last year and that we had a week of sushine. Some of you who know how I struggle to earn a living from my textile arts might think this a bit extravagant- but my aunt and uncle have been the best support over the seven years I have been going to Europe- and they- of all my family have best understood my need to create and teach. They have always stood ready to provide me with a bed ( and my children too when they have travelled with me), a wonderful cooked meal when I came home from teaching for a day, and Ed would unload the car for me,leant me their car when I needed it and their ear , and they have helped make it possible for me to get to the point where I am now- they are my unofficial patrons and I am totally grateful. I have worked hard the last few days packing up Across Australia and returning the quilts to their owners before I go. I had hoped to tour it some more, but it takes energy and time to make the arrangements and with my exhibition in Munich looming in August I have plenty to keep me occupied.I am going to Melbourne later today to return the Melburnian Across quilts and catch up with friends . I had to take a large suitcase into the post office full of parcels yesterday. If anyone is interested in a workshop for a day in Holland or Belgium or even France during February let me know-.Or if anyone is interested in my bringing hand dyed fabric let me know- my suitcase going over will be pretty empty.It all helps defray the cost of the airfare. Shirley asked about some of my process in making a lino-cut, so I thought I would share. As you all know I am having an exhibition later this year in Munich and I wanted the subject matter to include some of the things, images, feelings I encountered in Syria last year. The exhibition has the working title Carvanserai- which allows me scope, suggests the silk road, and other kinds of exotic rich experiences. I realise this is a rather romanticised image that I have built in my mind so I am researching to keep on track. One of the wonderful sights in Syria was a visit to Palmyra and the wonderful avenue built during during the time of Odainathus and Zenobia his queen widow, who was famed in the known world for her beauty, her astuteness in things military, her bravery, her knowledge ( she spoke 5 languages apparently) and her philosophical insights. I have read a number of things abot Zenobia and have been trying to find images of statues of her. The closest I can come is that the first two images on this post - they may or may not be Zenobia ( and the first statue I saw in the museum in Damascus). I also saw another two images which was part of an electronic text archive which are copyrighted. Scroll through the article and you will find two images of heads that were found on a dig in the nineteenth century. The first image on my blog, suggests someone less roman or greek, whilst the second image suggests much more classical structure ( and fine greek craftsmen were employed in the city). The two images on the linked article also suggest a more classical allusion however the first image has a headress which I find interesting. So then I drew what I found most interesting in all of these images. I transferred the drawing to the lino by simply drawing onto the lino. If the pattern were more formal i would probably transfer by tracing , but with this image I drew because I want the image to be mine, and you seem to refine and perhaps stylise with each time you draw. I then cut the lino- creating pattern and texture on the robe. and printed fabric with the image. The cut lines on the lino are quite fine- and indeed one bit has already been damaged ( which I will have to glue back) so these will be a limited edition doll. Some of the headress detail I liked in the linked article will come from beading and applied fabric. I know I have played with this kind of doll before but they turned out very masculine. I am hoping this doll will look much more feminine. So today I will sew some up and see hwat happens. This came in the post today! It's my 72 Ways book in French.It looks good with the coloured squares alongside the black and white squares and the directional drawings as well- it fills the page nicely! So thank you to Les Editions de Saxe for publishing it. Until they publish it in English I have the rights to keep selling my English version as I have been.And it would actually make an interesting coverlet as per the styling on the cover. It least it neats the pink and green quilt that I had to make for the cover of my last book-Tifaifai Renaissance which is now out of print. I have never been able to look at those cover quilts since. I also won Belinda Schneider's naming of her dolls on her Bel's Nook and I found a four leaved clover. Maybe it all portends well eventually. The top three photos are pomegranates I printed onto silk with Trapsuutjies Textile paint. The colour of the thread plays a big role in how these cards will eventually look. The bottom photo is a journal cover I made for a Mojo journal I bought in London a few years ago.It is free machine embroidery lace couched onto yellow fabric. I am finding it hard to get motivated at the moment- I hate it when I fee like this as I really need to be doing so much. And I should have put this on my blog earlier, but for any Australian quilt artist out there ( or New Zealand or South African ones) I am the Australian co-ordinator for a travelling quilt project, that will travel to New Zealand , South Africa and Australia and elsehwere. Anne Scott form New Zealand quilter is the Kiwi co-ordinator and organiser and Jeanette Botha is the South African co-ordinator. these will be selected from entries received. Finished entries are due 15 July 2008. can be stacked for ease of international freight. shown at various venues around the world. Gallery, Wellington during Symposium 2009. I have not done a stitch for over a week now and I really need to work on another coral variation for an article I am writing for the Dutch Quilters Guild magazine. I wanted to share the original inspiration for the Coral Variations. This tiny piece of something ( I think it is coral but I am not absolutely certain) was the inspiration. It measures about 1 cm across and I picked it up on the beach when we stayed at Turtle Beach in Queensland a couple of years ago. At one end of the beach was a rocky area which was a graveyard of broken shells and somehow I spotted this tiny fragment and picked it up. It was akin to finding a needle in a haystack. But it is also about looking- looking for possibilities, for form and lines that can be used as inspiration for work , to create something in another medium not as a faithful representation but as something that inspires a feeling . For me, this tiny fragment filled me with awe for its sheer beauty- so much contained within a tiny tiny fragment that once was life. For me this Expression is the crux of the matter- it is what i try and teach especially in my Inspiration in Fabrication classes. Looking is part of expression , learning to look is part of the journey, part of the process. Without expression things can be nice, with expression they can transport you to another place, another way of seeing ,to some form of understanding. For example rough stitching seems to have become a bit of a rage at the moment- and especially in contemporary quilts much more hand stitching is apparent now to say 10 years ago- rough stitching seems to be the used to express some form of individuality. However for whatever reason, unbeknowst to me ( because it certainly doesn't form any part of my housekeeping routine ) I stitch rather neatly- I can vary the size but I can't stitch rough- I have tried but it always becomes neat- there is a regularity in the rhythm with which I stitch and I suspect that is a determinant in the neatness- so is my work any less expressive because of this neatness? I am isolating an element of part of what i do but it is also llustrative of the fact that single elements do not a whole make- you need many things to create expression- and creating expression to me is all about communicating a feeling. Wow- I can't believe it. All but Forest #9 ( green forest fabric) has been sold. It is like you are all single handedly willing me to get this house! Thank you so much for the buying tyhe fabric and books I hope the fabric lives up to your expectations! I have been rock tying silk as I wanted to get quite a coloured piece of silk that I can hand quilt by accenting the tied bits somehow. I haven't yet worked out quite what or how I will stitch it, but I have a sudden need to get silk thread- can anyone suggest where I might get some white silk thread I can dye? But the fabric is seriously luscious even if I say so myself :-) I have also been using a blue colour from Kraftkolour called Ultramarine ( I normally use the mid blue of MXG blue) but I really like what the ultramarine does on silk. I also used it on some other forest fabrics which I will post in the next few days. I feel a bit of a fraud at the moment- I haven't done anything substantial for days and days now- I just can't seem to get the mood. The most I am managing is dyeing some fabric and a desultory stitch or two in my Palmyra palms. I just can't seem to muster any enthusiasm and things aren't helped by the fact that my favourite uncle ( the aunt and uncle I always stay with when I go to Europe) is in intenstive care in Ghent with a massive deterioration of his Parkinsons disease. I wish I could be there to help my aunt. I am glad that we went for a holiday to Italy last year when he was still able to do such things and then went to see some of their Austrian friends on the way home. My now ex thought I was on a jaunt- but they have always been so kind to me and store my things for me ,that it seemed a small thing to do as I could not get a flight home in any case. We scored a week of sunny warm weather and could eat al fresco on restaraunt terraces, and the Adriatic sea was perfect and calm and he genuinely enjoyed himself. I need to wake up with the spirit of enthusiasm and creativity bubbling tomorrow. I need to make somethings and lose myself in the process. On an up note- I have just noticed- the kookaburras seem to have wrested the backyard back from the crows who seemed to have chased of so much bird life this last 6 months. Their cawing swooping shapes sending a kind of dread into the garden. I love kookaburras and am glad to see them back- I like their laughter and they keep an eagle eye on any poisonous serpents that want to make the backyard home. I was thrilled to sell the forest fabric I posted yesterday so quickly- Thank you! I have put up three more pieces, about 1 metre square and 35 US for the piece ( or 24 Euros) inclusive of postage. I also got nominated by Shirley , Marion, and Sandra ( and you should go read Sandra's blog for her take on what it means to be an artists and be prepared to take belly laughs with you!)For Make My Day Award. Many thanks for this- it is good to know that people enjoy my blog! I will make some nominations tomorrow! I thought I might nominate bloggers that I had met throughthe internet- but I have to put the thinking cap on for that one! I have done little sewing these past few days. We went looking at display homes this morning. It is a bit disheartening, as most of the homes that we like ,are a bit ,actually quite a bit outside of my budget. They are very modest homes indeed, but I do want to have a good kitchen as I enjoy cooking, which also means pantry space if at all possible. I will keep looking.The size issue is affected by the fact that i work from home- I need space to work, as there is nothing available outside my home to rent to work in . One of the down sides of living in a small country village. I did buy some more lino to make some more lino-cuts for my exhibition later this year- hopefully I will get onto that tomorrow. And I will get up early and dye some more forest fabric as well, it gets too hot later in the day. I have bene dyeing Forest Fabric the last few days as a friend in France ordered some forest fabrics. I did a couple of different batches with slightly different colours. The fabrics are for sale . They measure 1oocm x 11 cm ( around 39 inches) and cost 35 US ( 24 Euros) inclusive of postage. Each fabric has a number underneath for identification. I always love ironing these bits of fabric- each one is so different. This is the type of fabric I used in the View from My Studio quilt with which I won a prize at Val d'Argent last year. I have finally finished another Coral Variation. This one is number 23 and is for sale. The price is 50US inclusive of postage. The background fabric has been hand painted and the lutradur has been transfer printed with a lino-cut. The second piece is hand dyed silk. It has been tied with rocks and has had several colours applied to it. It is 12mm weight habutai- which is really lovely for hand quilting and machine quilting but is not transparent like the 8mm habutai that so many of the silk scarves are made from . I have used it in a number of quilts and it looks sensational when it is lit by gallery lights or down lights.The piece measures 45 inches ( 114cm) x 57 inches ((145 cm). It is for sale for 175US inclusive of postage. The reason I am selling this one is because it is not quite right for what I had in mind but it is a seriously lovely piece of fabric. Now that I look at it on the photo there is a real sense of depth i nthe piece. And eek it is already day 8 of the new year, I had plans to make a small piece a day- so far the count is one. Oh well. Thank you for all your good wishes for the New Year! It was so hot passing through Melbourne yesterday so that we did not stop at an art shop as intended, and I didn't buy lino to make a lino-cut of the lamp/recess. However I have started hand quilting a piece I started awhile ago- before I went to Europe in September- my impression of palms and Palmyra and Syrian silks. Co-incidentally i found some drawings I did about five years ago in one of my journals of very stylised foliage from Assyrian carved reliefs. I wanted to combine those very stylised patterns with some of the palm patterns that were carved on the Roman ruins at Palmyra. I also used some silk in this piece which is modern woven silk using traditional patterns- I will show more images tomorrow.It is of course the worst time of year to be hand quilting with the temperatures soaring in high thirties and forties, celsius ( 100 plus in fahrenheit)- but I like to watch the tennis and hand stitching is something productive to do whilst watching the tennis.Alos the slowness of stitching byhand allows me to contemplate the next pieces I intend to do. I want to play with this image for anothe rlinocut. I am away for a few days visiting my mother in Gembrook- won't get any sewing done- but somtimes it is nice to have a break.
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I guess it's official now. Wife and i just closed on a 2013 36rl. Beat the dealer out of new G range goodyears and an automatic slider so we are still waiting on those to come in before we pick it up. I paid more than I planned but this one had most of the upgrades I would have done anyway. Full paint, G tires, disc brakes, satellite, dual batteries, toppers. The list is pretty long. Anyone know the history on this beast? Supposedly a couple from Wisconsin that traded for a DRV in Oklahoma. Not that a dealer would ever lie to me. Lol. I only got this picture and one other so far. All the others are pirated off the dealers website. I might post some of them later. Live just north of Dallas and trying to get positioned to go full time in a few years. We have previously owned a Toyhauler for our matching motorcycles so we aren't total nubes to trailering and camping but this is our first foray into the lap of luxury. Congratulations and welcome to the forum. I recommend that you read as many of the entries on this forum as you can. It will give you a great insight on your new RV. I am in Dallas but currently in my Redwood up in Wisconsin Dells for the month. What is an automatic slider? Thanks. I have been lurking for a few months while I searched for the just right one. And sorry, I meant a hitch that slides back automatically in turns because I have been known to have brain fade occasionally. Figured you guys could read my mind like my wife does. Beautiful coach and floorplan! Reminds me of the one we had. Sounds like you already have some of the upgrades others have recommended and that I have done to mine. This forum has a ton of good and useful information and suggestions - done by those of us who benefit from them. If you ever get to SW Tex, (Lake Amistad Area) Let me know. Congrats. and hope it works out for you ! Glad to have you on board. It's a head turner for sure. If you're getting a Slider Hitch, sounds like you're already starting off on the wrong foot, or should I say TV, unless you're talking Mega Cab Ram Dually. RLs are known for being Pin heavy, our '12 RL had approx 4K pin and 17K total, which puts you in Dually country. If you've been reading much you should have already about a few Members who started with a SRW TV with an RL and soon traded for a Dually. We loved our RL, but the MB floor plans fits our use better. We are neighbors, South Arlington, Kids went to Mansfield School district. Congratulations on your Redwood. We really have enjoyed our 2013 RL. Very few minor repairs by Redwood and then under Good Sam extended warranty. The major failure on our list was the slide/hydraulic pump DC motor. One power lead at the motor was loose damaging the brush holder and commutator bars. I op'ed to upgrade the entire hydraulic system with latest and greatest LCI system. The slides and leveling times were cut in half or more. Good Sam paid for the standard motor (900+) and I picked up the remaining 2,000 or so which included an improved DC motor. To that loose lead - l strongly recommend that each power and contol cable/wire be checked for looseness at the terminating point AND WITHIN ANY CRIMPED ON CONNECTOR in the battery compartment and storage basement (bedroom slide controller). Tug on the wire. Many of mine pulled out of their connector. After a session of replacing and tighting many loose connections I then grabbed a handful of plastic ty-raps and formed neat wiring bundles which then were supported to remove the wiring weight off the connection point. The circuit overload devices, located on the wall just above the rear battery had most all connections being loose at the stud or within the wire connector. The battery disconnect switch also should be checked for loose connections. While on batteries the disconnect switch only disconnects some loads. I completely remove the front battery front positive terminal cables. Keep those leads separate. I use a "booty" over each end as if they touch each other the battery can drain especially if you have a gen onboard. One of those front positive leads jumpers to the rear battery positive post. A battery disconnect at the battery is on my list. The installation of a Wingard SWM3 DirecTV satellite dish, on a supporting steel plate to protect the membrane roof was a pistol. The install only took about four hours on the roof (3-hours reading instructions and drinking coffee). The rest of the day was chasing down the coax connections, missing splitters and loose coax connectors. Thanks to many on this and another RW site I finally conquered the task. I replaced every coax connector as most were easily pulled loose. I chucked the E-rated tires and had 17.5" H-rated tires and a TPMS added after a significant blowout and the damage it caused at 62 MPH. The library on this site has many helpful manuals and owner insights that could help with your beautiful 36RL. Welome to our Redwood family.
This week Gary, Gary and Aaron discuss the importance of and how to cool and improve the pressure of your steering system to handle big tires in hot and/or demanding terrain. They discuss some listener feedback new in this week. And of course there is a famous Jeep of the Week. Tune in to hear a fresh new episode of the Northwest Jeepcast. Look for bonus content at patreon.com/nwjeepcast.
We always think outside the box and consider whether we can adapt good solutions to other industries and products. If that does not always work 100% - 50% is sufficient to find a one hundred percent good new solution. We are then satisfied, as you certainly are too?
some archives and institutions abroad. Discovery provides contact details for these archives and institutions. Visit Start here for advice on starting your research at The National Archives. Or find a research guide to help you in your research. Find out what Discovery, our catalogue, holds and what you can use it for. What information is displayed in the 'Records' and 'Record creators' search results tabs, how to understand a record or record creator description, and what to do if you have too few or too many results. How to save a search & find other possible matches. How to display simple and detailed view options, sort your search results and filter using the 'Records' tab. How to search for manorial records & documents, understand the search results, and the terms used in the MDR. How to find an archive in the UK and beyond using the map, regional lists, by country or by ARCHON code. A list of terms used within Discovery, our online catalogue, and their definitions. Understand what we mean when we refer to digital records and what a 'born-digital' record
Many brands are represented at Milan Design Week and Salone del Mobile, however, none are as exciting and trendy as the high-end furniture design brands. We know, that many of these luxury brands are Italian through and through, however, there are also some other honourable mentions you should know about. Take a plunge with us into the world of high-end furniture design. High-end furniture design, we all know some brands by name. But we can easily say that the Italians do have an upper hand in the industry. They have a rich history in high-end furniture design and have been on top of the game for centuries. Today we will take a closer look as to why this is. The italian design industry has always been characterized by sophisticated technology, outstanding, avant-garde design and colors. They are also well-known for custom designs and the use of quality materials. Lastly their use of excellent craftsmanship like the Murano glass blowing has made Italian high-end furniture in high demand by people world-wide. They may only be active since 2012, Roberto Cavalli home has already proven that they deliver excellent high-end furniture. The group offers a wide variety of interior design accessories and furniture, most of which has been developed in partnership with sector specialists. Also Fendi Casa is a well integrated name in italian high-end furniture design. They make furnishings for every place in your home and are able to seamlessly integrate modern innovations into retro details. Their collection always has that touch of elegance while still having an inviting vibe and brings that little bit of Roman Fashion House to your home with their pieces. As a key player for the evolution of modern technology and artistic tradition in high-end furniture design, Edra creates the most amazing furniture pieces. They have the production result that combines a blend of talent with specialized craftsmanship and innovative technologies and materials. Their pieces are unique and have an unmistakable presences due to the care that is put into the making of the products. Furthermore, their collection also includes sofas and cabinets that adapt to all kinds of spaces and fit in different kind of styles within your home or just public spaces. Antonio Lupi is known for its Tailor-made productions and stands out with their high degree in customization. As such they also want to include the highest standard for their brand. Not only do they want the highest quality, they also want to ensure the best customer care and include their passion into their work. For Missoni, however, their most important part of their high-end furniture is the fabric. For them, it creates a special visual which plays in on the emotions of their clients. They say that the right use of light and colour can make the perfect contrast and can give your furniture multiple facets, matt or silky, rough or soft all with one sort of fabric. Fabric is a support system for the design of the furniture, it gives an extra element to the product and makes the customer experience the product in a unique way. From collections containing art that blends with daily life icons to conveying their vision to their customer through a well-made message in the functionality of their furniture. Seletti is all about a fun and personal lifestyle. Founded in 1964, Seletti has always followed the same principle, namely striving for constant research and innovation, originality and the best professional service in the high-end furniture business. Names like Le Corbusier, Mackintosh, Lissoni, Pesce and Patricia Urquiola all ring a bell and they all have a connection to Cassina. In one way or another they have worked together on making amazing high-end furniture pieces that are a fusion between technological innovation and tradition craftsmanship. They are a pioneer in the industry thanks to their R&D work in collaboration with these architects, designers and icons of the design industry. B&B Italia has a history that includes the typical Italian style which has made them famous throughout their world. Their use of technology and creativity has made their products a big contribution to the Italian history of high-end furniture design. They have the ability to easily adapt to ever-changing lifestyles and habits, making their products always fulfill the requirements of their customers. As you now already know, Italy has a very good reputation for high-end furniture. However, there are some other international brands that are worth mentioning when talking about luxury in your home. Boca do Lobo is known for giving their customers an emotional experience with their products. They make beautiful pieces with passion and use handcrafted materials of the highest quality. The success of the brand has everything to do with the dedication of its craftsman and the knowledge they have in the industry. No part of the design process is overlooked and they have thought of every detail. Experience the journey yourself! Another great international brand is Circu. Built on a dream to give children the furniture for their dream bedrooms, Circu inspires the most magical of fantasies. Their products are hand-crafted and tailored and they ensure only to deliver the highest quality furnishings. As an innovator in lighting, accessories and furniture, Tom Dixon has constantly reinvented himself. From early eighties welding salvaged steel to radical furniture he has rethought the product designer's relationship with industry to improve it. The Portuguese design brand Brabbu has a diverse range of design pieces, from high-end furniture to casegoods and lighting, they all reflect the same theme of fierceness, strenght and power in the urban lifestyle. They bring a new sensory design to your home and pass on a unique experience every time. Maison Valentina may sound French in actuality it is a Portuguese high-end furniture brand for bathroom furniture. They aim to deliver the best and most exquisite bathroom designs and use the finest materials, the best craftsmanship and techniques to achieve that goal. With the way they make products, Pullcast tries to combine the worlds of jewelry and interior design to create sculptural masterpieces in high-end furniture design. They use elements of nature and a diverse range of styles, while also emphasizing the importance of sophistication. Essential Home is a mid-century furniture brand that has taken its inspiration from important historical and cinematographic reference from between the 1930s till the 1960s. As such their furniture pieces exude a unique and elegant vibe. They have also innovated the way they make the pieces with special techniques and the use of top of the line technology. Their products may have a mid-century feel, they still are quite modern and fit right into the luxury category. As many of the brands named above, Delightfull has added its fair share of innovations to the world of design. However, Delightfull is mostly focussed on the field of lighting with their high-end mid-century lighting pieces. They bring revivals from the 40s to the 70s while still giving the products a fresh, modern look. The award-winning designer, Piero Lissoni is internationally known for designing spaces with a vision for ambience and time. In his work, the ever changing world of italian design is reflected and the future of the design world can be seen. Piero Lissoni started his own company in 1986 with Nicoletta Canesi and has realised several groundbreaking projects since then. One of his best works was the amazing Laurent restaurant of the Hotel Cafe Royal and houses a spectacular Murano glass chandelier by Vistosi. The restaurant gives off an incredible relaxing vibe and falls in line with the contemporary lifestyles of today. Another important player in the world of high-end furniture designs and interiors is Dimore Studio. Founded in 2003, designers Emiliano Salci and Britt Moran hoped to make Dimore Studio a beacon for Italian Design. They focussed themselves on design, art and fashion an have collaborated with the greats to make the most amazing designs. One of those more well-known collaborations was the redesigning of a lot of Fendi stores. Fendi knew that Dimore Studio would perfectly represent the Italian essence of design in their stores and they did exactly that. Another top name in Italian design and international high-end furniture design is Antonio Citterio. In his youth he got inspired by the great Gio Ponti, but by now the student has become the master. Between 1987 and 1996, Citterio worked on a lot of big buildings in Europe and Japan after which he decide to become a more prominent figure in the world of furniture and industrial designers. As such he started working together with top Italian brands like Kartell, B&B Italia, Vitra, etc. For each of them he made atleast one piece that is in their most popular collection with his signature italian modern contemporary style. As an English interior designer, author and owner of Kelly Hoppen Interiors, Kelly Hoppen has made an incredible career for herself. She is one of the biggest names in interior design and has covered designs for hospitality to residential and yachts, aircrafts, offices and restaurants all over the world. Besides her home accessories brand, Kelly Hoppen Interiors, she also owns her own design studio, Studio Hoppen and is a recognised TV personality in the UK. As an admired product designer and one of the best interior designers, Marcel Wanders is regarded as an anomaly in the design world. His mission is to create an environment of love, alive with passion, so that it will make our most wonderful dreams come true. As such his work tends to excite, provoka and polarise people. However, we can agree on one thing you will always be in for a surprise. This French interior designer is not only one of the best, he also does it all. Projects for architecture, decoration, lighting and high-end furniture No problem for Jean Louis Denoit. His style is very eclectic, yet traditional and the inclusion of history in his design makes it just that tad more unique. The ancient craftsmanship that makes the high-end furniture high-end. The making of Murano glass or Venetian glass is a craft that was handed throughout the centuries from father to son. Throughout the years the way they used to work with Murano glass has also evolved, while still respecting the ancient traditions and integral customs. Nowadays, you can still only find the Murano glass on the island of Murano and the customs are still very close guarded. So, having a piece of high-end furniture is not only unique, it is almost an honour. As one of the oldest arts, Wood carving is an art of sculpting ornaments out of a wooden base. The product that is created from this holds a natural look and textures and yet can still also be found as being highly polished and in colored versions. Wood is an easily accessible product and is also easy to manipulate to the wiles of the artist or designer. Wood carving, however does require a good technique and there are even different carving styles to choose from. It may be a widely practiced art the wooden material doesn't last as long as other more durable materials. But that shouldn't stop you from getting a beautiful high-end furniture piece with wooden carvings for your home. Gold leafing or gilding is the application process of gold leaf on an object. It is ornamental decoration mostly for high-end furniture pieces and can be used on different materials and surfaces. Gold leaf is available in a large range of karats and shades and even has some substitutes like silver and copper. Just as wood carving, there are different techniques to the art of gilding. One of the most difficult ways to do it is by the traditional water gilding method, which has been unchanging and has to be done manually. However, adding a nice touch of gold leaf to some high-end furniture will only make the piece stand out for its uniqueness. Casting metal is an art by which you try to mold metals into a chosen shape and size. The process uses a mold to capture the shape you want and when solidified can be broken out of its cast. This is the most used technique to get the best realistic representation of your design. The most common metals used for casting are iron and aluminium. However, bronze, brass and steel are other varieties that can be used. Just look at some of the most intricate high-end furniture designs, they shine even brighter because of the metal casting that was used to make them. A last high-end furniture craftsmanship that is used in interior design furniture is the art of tile painting. This Portuguese art form is part of their cultural heritage and is most common in the blue and white tile colors. The art is a tradition that has been going on for over hundreds of years and is also known as Azulejo. They are made out of clay or ceramic and are mostly found in a square form. They are then decorated with colourful, glazed designs and the process is repeated a several hundred times to cover the base. It is mostly used in wall covering and architectural design. But it can easily be fitted onto high-end furniture pieces as decoration. Previous Top 5 highlights of Salone del Mobile 2019!
Tim Ingram wins the double! Over 80 members / members enjoy a night of Eagles music! Congratulations to West Hove GC Member Bob Smith for recording a hole-in-one on our 7th hole on Friday. Bob hit a crisp 6 iron into a strong wind which found the bottom of the cup! Well done Bob - your certificate will be ready and waiting for you at the club! Captain, Vice Captain & Professional take the honours! Our tree surgeons started work tidying up the trees in and around the members car park today, they will probably be on site most of the week and are working in small sections to avoid any inconvenience - see picture which shows how carefully the tree surgeons have to work, not for the faint hearted! Jonny Ingram Is In Sparking Form! West Hove Golf Club The New Bar! New bar project making good progress . Photo below shows wood stain being applied to the counter tops, undercoated all paintable wood and the back bar is starting to take shape - new flooring goes down today. The project is on schedule and we can't wait to open at 11am this Saturday! Bar refurbishment work started at 7am this morning - bar fitters, electricians, plumbers and cellar engineers are all busy at work. The plan is to have a new bar installed and fully operational on Saturday 10th September . Fingers crossed! Picture shows old bar being dismantled.
In Mrs. Prisana Heaton's classroom, large framed poster boards color the walls, each one explaining a complicated mathematics with an illustration. As a child, Mrs. Heaton was drawn to the subject of mathematics because of its innate logic and system of reasoning. Later in life, her passion for education and mathematics would bring her into a teaching role. One Saturday morning in late autumn, Keystone Academy held a Mathematics Relay competition for students in Grades 4 to 9. Students eagerly entered campus, ready to exercise their mental muscles with peers in order to solve complicated mathematics problems. Cultivating quantitative skills in the classroom and applying them to real world practices helps students feel confident in their ability to navigate the world. In addition, students feel inspired to challenge themselves academically and intellectually. Please find below an interview with Mrs. Prisana Heaton, the trail blazer nurturing students with a budding interest in mathematics to pursue their passion for the subject. Q: What are the greatest merits of learning Mathematics? How do students apply math techniques at this age in the real world? Math teaches students problem solving skills creative, critical and logical thinking, how to be organized and improve their communication skills. Knowing basic arithmetic and understanding the calculations behind the real-world applications ensures that we are aware of what is happening around us. Checking that the correct wages and taxes have been given or service fees charges are right helps us to understand different systems of governance. Understanding finances helps us plan for the future so that we can retire comfortably and not stress about a roof over our heads or where our next meal will come from. Q: What was the purpose of the Mathematics Relay at Keystone? The Keystone Math Relay allowed students to practice competition style questions that require collaboration, critical thinking and creative thinking in order to find the solutions. In many math competitions like AMC, Math League, ACAMIS, NEAMC, etc., the school can only have 4 8 representatives. These competitions don't give our other talented students a chance to show us what they can do. The Keystone Mathematics Relay is a group event that allows students who are not as confident in mathematics to still have fun and learn from their peers. Solving unfamiliar word problems using their existing math knowledge is part of the curriculum. Exposing students to these types of applications builds a stronger foundation and helps students feel more confident about using mathematics outside of the classroom setting. Q: How did the students prepare for the competition? Why are these types of events important? Students were given two sets of Relay style questions, for each division, both from last year's Math Relay competition. They were asked to meet up with their teammates prior to the event and work on solving the questions together. During the Math KAPs, the students also worked on these problems and competed as teams. The math teachers allocated times during their lessons to work on these problems. Events like these are important because students get to practice the skills they learned in class to solve unfamiliar questions. It helps build confidence and also allows them to solve questions that are not in the textbooks. Also, this kind of event doesn't have the same pressures that a classroom test has if they don't do well there is no downside this allows them to focus on the mathematics process rather than the results. Q: How do you plan to arouse more interest in Mathematics at Keystone in the future? What events would you like to see happen at the Academy related to Mathematics? In the first year of the Math Relay we had approximately 90 G6-9 students compete in the hour-long event. This year we had nearly 240 students. The big growth of participants showed that our students enjoy mathematics even though it can be challenging at times. These events promote collaborations and communication between our students. It allows our students to be risk-takers, accepting that failure and success are all part of life's lessons. Students learn from their mistakes and then celebrate success when it occurs. I hope to continue the Math Relay event for grades 4 9 in many years to come. In the future, perhaps we can hold it once a semester instead of once a year.
Water plants that are suitable for the middle ground are the most varied group for aquascapes or planted tanks in general. Many plants that grow to a larger height are also suitable for the middle ground if they are trimmed back on a regular basis. With narrow-leaved aquatic plants like Ludwigia arcuata, Pogostemon erectus or Rotala sp. ?Green? you can build attractive groups in your aquascape. A great number of Cryptocoryne species is also suitable for the middle ground, and their leaf forms and colours contrast beautifully against stem plants. Medium-sized ferns or Anubias variants are also suitable middle ground plants. In aquascaping, the middle ground is where you place your hardscape (driftwood and rocks), which in turn can be planted with mosses or epiphytic plants. The middle ground is the most important area in an aquarium or aquascape, because from a design point of view, it is naturally the most eye-catching. Here the design possibilities are particularly varied. Lots of various aquarium plants are suitable for middle ground planting. In our online shop we offer a rich selection of such plants; Aquascaping enthusiasts and plant aquarists as well as "normal" aquarium owners get their money's worth with us. Fast shipping contributes to the high quality of our aquarium plants. You can also buy rare plant species for the middle ground from us online - some of which we cultivate ourselves. The growth height, but of course also the height of the aquarium tank and the desired design style play a role in determining which aquarium plants are suitable for the foreground, middle or background; of course, no sharp boundaries can be drawn here. The selection of stem plants is particularly varied, as the growth height of these can largely be regulated by pruning and replanting shoot tips. For example, with different Rotala-, Ludwigia- and Alternanthera-forms, multicoloured or fresh green bushes can be created, which also transition between the back and foreground of the aquarium with their stepped growth height. Skilful selection of different textures and leaf sizes is one of the means of increasing the depth effect in aquascaping. Exotic plant forms such as Tonina fluviatilis and Syngonanthus macrocaulon come from the Eriocaulon-relationship; they are a special attraction as a group in the middle ground of the aquarium. Some strictly upright, slow-growing stem plant species such as Lindernia sp. "India" and Rotala indica look best if they are not allowed to grow taller than 10 to 20 cm. Even low, bushy, spreading aquarium plants like Staurogyne repens and Limnophila sp. "Vietnam" have their right place here and are suitable for harmoniously connecting the fore- and middle ground areas of the aquarium. We provide help with the handling of stem plants in this Wiki article. For rosette plants such as Echinodorus, Cryptocoryne, Lagenandra and Eriocaulon, on the other hand, the maximum height that a plant species or variety can reach must be taken into account. Especially water trumpets (Cryptocorynes) often reach their maximum height only after a period of long, undisturbed growth, for example Cryptocoryne cordata var. siamensis can reach a length of over 30 cm. Lower, more dense stocks are formed by the proven, undemanding cryptocorynes from the Sri Lanka group (Cryptocoryne wendtii, C. beckettii, C. undulata and C. walkeri), which are also extraordinarily diverse. Their spread through sub-substrate runners can be limited by planting them in small containers, such as plastic cups buried in the substrate. Very attractive are also the cryptocorynes with very narrow, band-like leaves like the rare, light green Cryptocoryne spiralis var. caudigera ("Shola") from India and the brown-grained Cryptocoryne albida "Brown" from Southeast Asia. Most sword plant species and varieties (Echinodorus) work best as solitary plants. A free-standing, extensive echinodorus leaf rosette sets a strong accent in the aquarium. There are various rather small sword plants like the deep dark red Echinodorus 'Reni' and the light to medium green real Echinodorus schlueteri (in trade mostly as Echinodorus cordifolius 'Mini)', but also very high growing forms like Echinodorus grisebachii 'Bleherae' can be placed in the middle ground, provided there is enough space. Of all stolon sword plants, Helanthium bolivianum 'Vesuvius' with its very narrow, tightly spiralled and twisted leaves is particularly decorative. Water sprites (Ceratopteris thalictroides and Ceratopteris cornuta) are magnificent solitary plants, as well. Differently to what one would expect from ferns, they are extremely fast-growing. They grow into large bushes with light green, feathered leaves and are easily propagated by adventitious plants on older leaves. Although it is a stem plant in structure, the Japanese threadwort, Blyxa japonica, has much in common with rosette plants in appearance. This genuine underwater plant forms magnificent grass-like stands in the middle ground in light green to reddish tones and is one of the most popular plants in aquascaping. The Eriocaulon sp. "Feather Duster" forms very fine-leafed, higher "grass bushes". Eriocaulons are generally considered to be quite demanding, but this is by no means the case with this remarkable plant. Also Eriocaulon sp. "Vietnam" turned out to be extremely undemanding; this plant is probably suitable for almost every freshwater aquarium and deserves much more popularity in aquaristics. The hardscape, i.e. decorative materials such as stones and roots, is usually placed in the aquarium's middle ground, but often forms an organic unit with the background. Epiphytic plants such as Anubias, Bucephalandra, Schismatoglottis roseospatha, ferns and mosses find their ideal habitats on the Hardscape and are particularly nice to look at there. They therefore also belong to the aquarium plants suitable for the middle ground.
The town of Guildford in Surrey is known for a fantastic shopping experience. Of course with the Guildford business park and easy access to two popular airports in Heathrow and Gatwick. Your Advanced Microsoft Access 2013 Training Course training course in Guildford Surrey can be conducted at your premises, where we can bring laptops with the Microsoft Access 2013 Training Course already loaded. We can even bring a projector along with power extension leads, leaving you to concentrate on learning. Conducting Microsoft Access 2013 Training Course training courses in Surrey is a relatively new venture for us so please try us out and remember to tell us and others what you think.
The Newburgh Free Academy Goldbacks defeated Middletown High School 94-76 for a OCIAA Division I win on Friday, February 19, 2010 in Newburgh, NY. The scoreboard shows Newburgh Free Academy Goldbacks defeated Middletown 94-76 for a OCIAA Division I win on Friday, February 19, 2010 in Newburgh, NY. Hudson Valley Press/CHUCK STEWART,
An overview of a typical crime laboratory and the responsibilities for each of the sections of the lab will be provided. Discussions will include a definition of forensic science, how different scientific disciplines integrate to assist investigators in resolving inquiries of a legal nature, and examples of crime scene reconstruction. The role of the forensic scientist as an expert witness will also be discussed. The Network for Earthquake Engineering Simulation (NEES) laboratory, at the University at Buffalo, is a part of the Structural Engineering and Earthquake Simulation Laboratory (SEESL) within the Department of Civil, Structural, and Environmental Engineering (CSEE). The laboratory is capable of conducting testing of full or large-scale structures using dynamic or static loading. This is enabled by the availability of two shake (earthquake simulation) tables; large-scale dynamic and static servo-controlled actuators; and a 40-ton capacity crane. Participants will hear a presentation describing this very unique facility and observe an example of the nature of seismic testing using a "Mini-Shake Table" prior to the tour of the laboratory. Students will tour the University at Buffalo's Fronczak telescopes and learn about observational astronomy. "Touch, Play and Think" about some of the science in your everyday world. All too often we go about our lives not thinking about the principles of science that impact what we do and how we perceive the world. Learn more about how science plays this role in your life, even though you might not even think of it. This presentation will be an introduction to the field of cancer Cytogenetics. The genomes of cancer cells are very unstable, often characterized by gains/losses of whole chromosomes and rearrangements between chromosomes. This specialized area of chromosome analysis examines the genetic changes that occur in the cells of cancer patients. Students will receive instruction in this cutting-edge field of genetics. The relevance of these findings to patient diagnosis and prognosis will be discussed. Students will be shown techniques used in the laboratory and will be given the opportunity to cut-out an actual karyotype. Interested in chemistry? This session includes tours of two research laboratories under the direction of Professors Frank V. Bright and James F. Garvey. In exploring these state-of-the art laboratories, students will learn about ongoing research activities, laser-based instruments, applications of chemistry research, funding sources, and the central role that student scholars play in university research. Learn to read the clues that animals leave behind and solve the nature mysteries in your own backyard. Hands-on investigations will include real biofacts from native mammals, birds, and insects. OK, so you know your toilet is made from ceramics and you know that the cups and plates in your cupboards are made from ceramics, but did you know that the soldiers fighting in Iraq are wearing ceramics to protect them against gunfire? Or that if you have to inject yourself with an Epi-pen that it is a super strong glass vial that protects the medicine within? Or that ceramic components are responsible for ultrafine movements in your cameras and watches? A bit different from the good old sturdy pedestal sink wouldn't you say? Ceramics are some of the oldest materials in existence and yet they are the new "it" material. Come and hear more about the "ringer" of the material world. Jumping Asian carp? Beach fouling bivalves? "Ruffe" times for fish communities. Vampires of the Great Lakes? This program will offer a look at zebra mussels, the ruffe, and other exotic species that have invaded the Great Lakes. Learn about blood-sucking lamprey that feast on trout and other fishes, and what is being done to control these "vampires" of the Great Lakes. Tour the NYS Center for Engineering Design & Industrial Innovation (NYSCEDII) for an overview of the state-of-the-art in visualization and virtual reality. Also see some academic and industrial applications the center has been involved in over the past year. The center uses state-of-the-art graphics technology to immerse users in virtual worlds. View a three-dimensional model of a saber-toothed tiger skull, watch the motion of a child seat in a car accident, and move 100-foot tall pressure vessels around to design a chemical plant. The University at Buffalo's Center for Computational Research (CCR) is one of the leading academic supercomputing and visualization centers in the U.S. The Center's machines have a peak performance of 13 Tflops (trillion operations per sec), and can do in one day what a high-end PC would take more than 6 years to accomplish. CCR's computing and visualization infrastructure supports research in a wide variety of areas, including chemistry, biology, physics, mechanical engineering, aeronautical engineering, civil and environmental engineering, bioinformatics, media, finance, art, architecture, medicine, animation, and management. Dr. Furlani will give a PowerPoint presentation that discusses the Center, its capability, and the research it supports at UB. Finding your way around the night sky via a portable planetarium, participants will observe projections of constellations, stars and galaxies. Learn more about the nature of the universe. Have you ever wondered where tap water and bottled water come from? Tour the drinking water research facilities at UB to see demonstrations of the science behind drinking water treatment. Find out why prescription drugs may actually show up in drinking water. Groundwater is all around you, but because you cannot see it you may not realize how important it is. Learn about the basic principles of groundwater. where to find it and how it flows. Students will learn why groundwater rivers do not exist and how scientific tools can be used to answer many practical groundwater questions. An innovative software demonstration will allow students to follow groundwater flows at a microscopic scale. 14. PHYSICS TOUR _ "COSMIC RAYS" Particles that bombard the Earth from anywhere beyond its atmosphere are known as cosmic rays. The origin of these particles, some of them with extremely high energy, is not fully understood yet. This lab tour will show you a "detector" of these particles and various ways to study them. In particular, how cosmic rays can help physicists to understand properties of "elementary particles" that are building blocks of matter. Tour and learn about "Medication Experts" in action. The tour will begin in our Pharmacy Museum and Turn-of-the Century Apothecary, where you will see how pharmacy was practiced during the 1800s and early-to-mid 1900s. "Cigarettes for asthma," a prescription for alcoholic beverages (used during the Prohibition). The Department of Biological Sciences is a primary focus for instruction, research, and service in the basic biological sciences. The department provides rigorous training at the undergraduate and graduate levels and research in pursuit of new knowledge. Tour the Biological Sciences laboratories to learn more about cutting-edge research being conducted at UB. Interact with a NASA scientist and learn about National Aeronautics and Space Administration's Earth Science missions. NASA Scientists look for the answers some basic questions: What's out there in space? How do we get there? What will we find? What can we learn there, or learn just by trying to get there, that will make life better here on Earth? The session will be highlighted with equipment used in the NASA space program. This videoconferencing event is an overview of NASA's current and future plans to send humans to the planet Mars. Earth-Mars transit space propulsion systems (nuclear thermal and nuclear electric), space environment concerns, how people would live on the Martian surface, and initial colonization plans will be discussed. Current status of the ongoing robotic mission (Global Surveyor) and the role of the NASA Glenn Research Center during this effort will be explained during this session. Slide presentation featuring a revealing and entertaining look at such mysterious phenomena as the ghost at Mackenzie House and cases of alleged "spontaneous human combustion" - all from the speaker's own case files and all examined from the scientific point of view. 20. FIGHTING A BATTLE: WHAT'S A WIN AND WHAT'S A LOSS? Professor Sen will show how one can simulate the start, progression and outcome of a battle and point out that it may be possible to understand diverse processes such as colonization and occupation of a territory, short term victory and long term loss in a battle, and why some diseases proceed rapidly, some slowly and some can't even be felt, in real life. Identification of new proteins and gene products and visualizing their spatial relationships with known cellular structures has become one of the most powerful methods in understanding cellular function. Learn about the confocal microscope and related technologies the have been central in this effort. Microscope image formation and the principles behind the use of the confocal microscope will be presented along with examples of instrument capabilities showing how three-dimensional views of the cell are generated. We think that we occupy a special place among the wonders of Nature. What makes us so special? Is it because we have the ability to think? If today's best computers are not as good as humans, are they as good as flies, or bacteria, or viruses? Are we really superior to chimpanzees, or monkeys, or even flies? If we are, is it because we have consciousness and the lowly animals do not? Do chimpanzees have consciousness? Do flies? What about bacteria? Are we superior because we have the ability (the free will) to do what we please to? Can we really do what we want to, or are we puppets in the hands of some unseen force(s)? Such questions lead us into endless intrigue and mystery, and reveal our profound ignorance on the nature of our beings. Bring your own intriguing questions to the discussion. Students will be taken on a tour of the Physics and Arts Exhibit at the UB Physics department. The students will use hands-on exhibits to learn about the rotation of the earth, the light emission from stars, AC power generation, fundamental optics and particle physics. The electrical engineering program emphasizes photonics, communications and signals, digital electronics, micro-electronics, and materials. The tour will focus on demonstrations within Electrical Engineering Laboratories including the Microwave Lab, the Microelectronics Lab, the High Power Electronics Lab, and the Laser/Photonics Lab. Take an imaginary journey beneath the sea to learn about the incredible creatures that live in the world's oceans. From the great whales to the colorful fishes of the coral reef, learn about some of these unique creatures and the changes that humans are causing in these watery environments. "BEYOND THE TWILIGHT ZONE: FLESH-INVADING FLIES" This presentation will focus on a bizarre but fascinating phenomenon in medical entomology called myiasis. Myiasis is the invasion of a living vertebrate animal by fly larvae. Using real case studies from his work as Regional Entomologist with the New York State Department of Health in Buffalo, Dr. Gall will outline the biology and medical significance of flies involved in human myiasis, including the human bot fly, rodent and rabbit bot flies, the sheep nose bot fly, etc. A collaboration of UB students, community members, government and industry have worked to answer questions about pollution in local environments. A review of efforts in three Buffalo neighborhoods will be given, including Hickory Woods and Seneca Babcock, along with successes in citizen design of cleanups on East Ferry. A review of the Niagara County community of Lewiston Porter project will also be given. In all of these projects, the ability of the community to understand and participate in the planning, execution and interpretation of scientific results improves the way we deal with environmental issues. Students, community members, government and industry participants all benefit from the college/university collaborations. How do meteorologists know when and where it will snow? Greater refinement in extended range global models now enable meteorologists to make weather forecasts which were not possible 10-15 years ago. Learn about the capabilities and limitations of these models from an expert who uses these important tools. The mystery of Bigfoot has been explored for decades without resolution. Yet the question of Bigfoot's existence is less a matter of belief than one of science. Discussion includes the search for the mysterious creatures, theories about them, and the reasons that most scientists doubt that Bigfoot exists. A clinical presentation using actual case photos of the most common sexually transmitted diseases such as Gonorrhea and Herpes, as well as some of the less common sexually transmitted diseases such as Chancroid and Lymphogranuloma venereum. Recent global warming has occurred at a faster rate than most scientists expected. Rising seas, changing weather patterns, melting glaciers, and extinction of species are some of the observable effects of climate change. This dynamic presentation will cover the implications of global warming. Bag lunches are strongly recommended! ©️ 2019 Science Exploration Day. All Rights Reserved.
This is a marvelous property located in the heart of West Meade Hills Subdivision. It is a single level, ranch style home built on a flat, beautiful lot. This home backs up to an area that will forever be open, so it affords a very peaceful back yard ideal for relaxation or noisy kids. This home has had some renovation providing for a very nice master bedroom. Newly painted exterior. Come out and see. It won't last long in this very popular neighborhood. Directions:1-40 West to Charlotte Pike exit near Nashville West. Turn right on Charlotte Pike. Just past Cracker Barrel, turn left on Davidson Dr. Go to 3rd street on right which is Windrowe Dr. House is on the right.
Kourtney Kardashian was spotted leaving music class in Beverly Hills with her children Reign & Penelope on March 17, 2016. Penelope was dressed for St.Patrick's Day in a green satin dress, which she paired with some cute Mary Janes. Kourtney juggled Reign, her phone and Penelope's bedazzled bag as she headed to her SUV. Later on she shared a photo of herself with the kids having lunch. On Friday, the busy mama reunited with her ex-boyfriend Scott Disick to get a sneak peek of the new Harry Potter World at Universal California. Penelope is one sweet wizard!
This great the plane feels great graphic are amazing. Really like it thanks.
deid scrubs free-text records by masking or removing identifiers. The package includes the code and dictionaries for automated location and removal of protected health information (PHI). The app requires prior Perl 5 (or later) installation. For mac users, no need for further installation. For Windows users, please use "perl -v" command on the commandline to check if Perl is available. If not, please install this. For more info, see its Manual. Finetune the app for your needs by modifying its dictionaries and lists of names and other identifiers. This app requires prior Java installation. Check here to verify if your computer has Java. Deidentify is a buggy app. But it's a good code base for further development. If "Process File" option doesn't work, use "Batch Process" instead.
The weekend before he was murdered, UNC dental student Deah Barakat placed a surgical mask over his face, hoping it wouldn't frighten the 4-year-old boy in front of him. The boy, wearing a red Spider-Man T-shirt, gazed curiously at Deah, who smiled behind the mask. Deah, clad in blue scrubs and a friendship bracelet, laid out four Sesame Street stickers, allowing the boy to pick his favorite. Then the 23-year-old Deah displayed two toothpick-sized rods, each with an oval sponge at one end. "These are lollipopsone for me and one for you," Deah pretended. "Now, I'm going to count your teeth with my lollipop, but I need you to hold onto yours as a backup." The boy was most likely a family member or acquaintance. Deah was using him as a practice patient, in preparation for field work in March. The work involved collecting saliva samples from young children to determine if they had a genetic disposition to cavities. The exchange with the boy was captured in one of the last photographs taken of Deah before a gunman executed him Feb. 10 alongside Deah's newlywed wife, 21-year-old Yusor Mohammad Abu-Salha, and her sister, 19-year-old Razan. There are lingering questions about the tragedy. Questions involving parking and vigilantism. Mental illness and gun ownership. Religion and hate. But in reflecting on the triple-murder, some have preferred to focus on the things that are certain. Things like kindness, hard work, and the power of a smile. Deah had enrolled in UNC to help poor children without dental care. For the past year he had provided free screenings, supplies and food for homeless people. His plan was to open a practice with Yusor. They were young and in love. The boy in the Spider-Man T-shirt opened his mouth. Carefully and tenderly, Deah swabbed the boy's gums and tongue, pretending he was counting his teeth. "One . two. three," Deah said, as he prodded the boy's mouth for saliva pools, periodically squeezing the droplets into a receptacle for DNA extraction. The project was part of a larger one run by Deah's UNC adviser, Kimon Divaris, who had already collected hundreds of samples from North Carolina children. In a first-of-its-kind study, Divaris' research group is identifying the biological causes of oral decay in preschool-aged children. Deah had asked Divaris to assist. The two men quickly realized they were kindred spirits. They shared the same interest in community service, public health, and pediatric dentistry. They both loved basketball. After Deah joined the research team, he often stopped by Divaris' office to discuss the Milwaukee Bucks. Both men also had back problems. When Divaris complained about his, Deah recommended his chiropractor. One afternoon, when Divaris walked into his office, he discovered a gift from Deah: a plastic back scratcher. It came with a note: "To the best mentor." Deah recently had shifted his attention to global health. He had already served on a dental aid mission in Palestine, and he was raising money for a trip to Turkey, to provide services and supplies to child refugees from war-torn Syria. In a YouTube fundraising clip, Deah appears in front of the camera, explaining that with proper care, the Syrian children's lives can improve. "Let's relieve their pain," he says. Last year, Deah completed his first journal-qualified paper, in which he analyzed the data from Divaris' saliva samples. Deah studied more than 200, determining which ones generated accurate DNA information. He also assessed the feasibility of taking saliva samples from children, who are often too anxious or preoccupied to handle a "lollipop" swishing inside their mouths. Earlier this month, Deah visited Divaris. The data analysis was going along fine, said Deah, but he wanted to join Divaris in the field, collecting kids' saliva samples at schools, churches and Head Start programs. Divaris, who had already welcomed the idea, handed Deah a saliva-extraction kit. "See if you can find a friend or family member to practice on," he said. Deah left the office thrilled. During the next few days, Deah and Divaris exchanged a series of emails. "Let's chat more," Divaris wrote in an email on Tuesday. "Gotcha!" replied Deah at 2:20 p.m. His signature included a photo in which he flashes his contagious smile. More than 5,000 mourners traveled to a N.C. State soccer field to view the caskets of Deah, Yusor and Razan. They were buried in an Islamic cemetery in Wendell. Since their deaths, hundreds of thousands of dollars have flooded a fund to build new dental clinics in Turkey, Jordan and Raleigh in their honor. A clinic in Reykxanly, Turkey, built for Syrian refugee children in Deah's name, opened last Thursday. This week in his office, Divaris memorialized his late student. "We're already trying to think what he would like us to do: engage in the community, make a positive difference, and do it quickly," the professor said. Deah's legacy will inspire students for years to come, he added, pausing once to choke back tears. Nearby, the back-massager Deah gave him hung on a shelf. Deah will be remembered for many things: His hugs. His enthusiasm. His diligence. His maturity. His ability to identify a need and find a practical solution. But one thing seems to stand out. "Deah's smile is what most people remember," said Divaris. And though it was short-lived, it's fitting that he entered a career dedicated to brightening those of others. This article appeared in print with the headline "A million-watt smile."
my insurance co going to react to a not yet over the limit refill? Wow! She really overstepped her bounds. Sorry this happened. Tramadol is NOT an opiate. To be classified as an opiate it must come from the poppy plant. Tramadol is a narcotic analgesic. The pharmacist was way out of line pharmacists need to remember their job is to fill scripts that doctors write. The only reason they should contact the physician is if you are obviously over medicated which it seems you were not. Find a new pharmacy and maybe a new physician. It is completely wrong how we are all being judged because of the actions of others. Have you ever considered the herb Kratom? I was able to discontinue Fentanyl (a true heavy opiate) with the aid of Kratom. Feel free to PM me if you want more info. I have been in healthcare for over 20 years.My specialty was cardiology. I had to give up my career because of health issues. I also use pot when needed particularly at night. Tramadol is classed as an opioid. I guess She really wanted to be a doctor and not a pharmacist. I've come across this many times with pharmacists wishing they were doctors.Lol what happened To the days when doctors were doctors and pharmacists were pharmacists? She was out of line and I would talk to the manager over the pharmacists. That needs to be explained to LMB as she seems to think she knows it all. Receiving private messages from her filled with rudeness and insults. Tramadol is a schedule IV medication in US. I've had nearly every prescription medication for pain. It's nuts. So much trouble getting them filled, drug abusers, people calling me an addict. I refuse to take anything stronger than Tramadol. Doctors try to prescribe stronger, I go off on them! Less side effects ie less constipation.
It was Christmas lunch at Amanda and Richards' house today, in the village of Mabe, just outside Falmouth. We would like to thank everyone who has sent their best wishes to us at this time of year and we wish you all a happy and successful 2010. They must be celebrating Christmas early in Kingston, Ontario, with the news that Queen's University Mining Department has received a 10 million donation from mining entrepreneur Robert Buchan (left). It's the largest single donation to mining education in Canadian history and will help drive the development of the global mineral resource industry. In recognition of this exceptional gift, the department will be renamed the Buchan Department of Mining. The full story is on MEI Online. Maintaining the momentum of last month's Flotation '09, which was attended by 193 international delegates, the next scheduled flotation conference has already attracted 3 corporate sponsors. Two of them, Maelgwyn Mineral Services and FLSmidth, sponsored Flotation '09 and are strong MEI supporters, Maelgwyn also sponsoring Precious Metals '10 and FLSmidth having sponsored this year's Physical Separation '09. Martyn Hay's successful one man company, Eurus Mineral Consultants is a new flotation sponsor. Martyn presented an excellent paper at Flotation '09 and also sponsored Nickel Processing '05. The website for Flotation '11 is up and running and we look forward to working on this major event over the next couple of years, with our two MEI flotation consultants, Profs. Dee Bradshaw of JKMRC, Australia, and J-P Franzidis of University of Cape Town, South Africa. After the predictable fiasco of Copenhagen, the question is where does this leave the minerals industry, one of the world's greatest emitters of CO2 and under intense pressure to reduce those emissions? The failure to arrive at binding legal agreements, merely producing expressions of intent, will fuel the global warming deniers who will use Copenhagen to show how politicians are happy to embrace anthropogenic global warming (AGW) theory to collect green taxes, but when it comes to the big crunch they do basically nothing. There is a big difference between a denier and a sceptic. The former often has little scientific knowledge and may have vested interests, in the same way that the tobacco companies once denied the link between smoking and lung cancer. There is nothing wrong with being sceptical, as scientists should question the science of other scientists. Most scientists that I speak to agree that humans play a part in climate change, but are unsure of the extent of human input. The Royal Society's committee on climate change is very much pro-AGW, but when I pushed one of their senior men some time ago as to what extent humans have contributed to temperature increases he said that he thought that AGW might have contributed about 90%. This may seem a very vague response, but it is a sensible one, as in truth nobody really knows the human contribution. The important point is that if we agree that to some extent we contribute, then the exercise reduces to simple risk management- I don't expect my house to catch fire today, but I pay the insurance just in case- it is too risky not to do. So I ask the question again. What does the minerals industry do now- proceed with expensive schemes to reduce emissions, such as carbon capture and storage, or do as little as possible and make hay while the sun shines (ever hotter)? These are questions that I hope will be asked and hopefully answered at Climate Change '11 in Falmouth. I have just given Elsevier the go-ahead to proceed with publication of the next special issue of Minerals Engineering- Sustainability, Resource Conservation and Recycling, which will be published in March (Volume 23 Issue 3). This will contain 15 selected papers from SRCR '09, which was held in Cape Town in April, and has been ably guest edited by Profs. Markus Reuter (Ausmelt Ltd, Australia) and Kari Heiskanen (Helsinki University of Technology, Finland). The next conference, SRCR '11 will be held in Falmouth in May 2011, immediately followed by Climate Change and the Minerals Industry '11 and Risk-Based Approaches to Major Decisions '11. It promises to be a week not to be missed! I was browsing the October issue of the Journal of Southern African IMM this morning and came across "A Letter from London" by Prof. Jan Cilliers (left) of Imperial College. Jan points out that in terms of actual operations and tonnages the UK is not much of a mining country any more (although there may be an exciting new polymetallic mine in Cornwall soon). It does, however, have an enormous influence, London being the home of head offices of a number of major mining houses, and the UK has a very strong mining and mineral processing research presence internationally. None more so than Jan's impressive team of young researchers at Imperial College, who were out in force at last month's Flotation '09 conference in Cape Town, presenting 7 high-quality papers. Jan must be congratulated on bring together such enthusiastic and bright young people. Just over a year ago Rio Tinto announced a major partnership with Imperial College, creating the Rio Tinto Centre for Advanced Mineral Recovery. The Centre is a research hub in which world class scientists are developing innovative technologies to improve mineral extraction and recovery, while minimising environmental impacts. The Imperial partnership is one of three that Rio Tinto has established, and the only one outside Australia. The Rio Tinto Centre currently runs four projects, each over a 5 year lifetime. Two projects are in mineral processing: froth flotation and leaching, and two in geophysics. Complex computation is a major component of each of the four projects. Keep up the good work, Jan et al. I see Amanda is tweeting again on Twitter (am I going mad!!). November 13-14 Zinc Processing '10. There are calls for papers for these 3 events, and abstracts should be submitted by the end of June. Cornwall has an illustrious history of metal mining. In the 19th century the county was the world's biggest producer of copper and tin. The demise came with the discovery of large porphyry copper deposits in the Americas, and vast alluvial tin deposits in South East Asia. Copper mining effectively ended in the 19th century, while tin mining carried on at the deeper levels, the final mine, South Crofty closing down in the mid 1980s. Now there is hope of a revival. I was talking to one of my ex-CSM students, John Webster at the CSM Lunch on Saturday. John, who left CSM with a Higher Diploma in 1980, has been recruited by South Crofty's new owners, Western Union Mines, to bring the mine back into operation within the next two years. Originally South Crofty mined a narrow vein of cassiterite, in contact with the granite host rock, to produce tin and by-product tungsten. However various other ore-types have been discovered, containing copper, zinc, silver, lithium and indium, which could make South Crofty a true polymetallic mine, that could take advantage of fluctuations in metal prices, rather than be at the mercy of tin prices. The next phase of operations will involve de-watering and WUM is working closely with the Environment Agency to ensure that the process is carried out in line with strict environmental regulations. John is confident that the future is looking very bright indeed and Cornwall will very soon become a world class base metal producer once more. Barbara and I have just spent a very pleasant afternoon in the old tin mining town of Redruth, with 60 members of the CSM Association, for the annual Christmas lunch. It was good to catch up with old friends, including my old mineral processing colleague at CSM, Jim Turner (left). Jim is now in his 80s, and the photo below shows Jim with two other octogenarians, who I first met on the staff when I arrived at CSM in 1974, John Shrimpton, head of mining, and Ron Hooper, head of surveying. It's hard to believe that this time last week Barbara and I were in South Africa, Jon in Namibia and Amanda in Spain. This week has been intensive catching up- responding fully to all emails, allocating referees to Minerals Engineering journal papers and collating abstracts submitted for Comminution '10. This is looking good and is on track to being as successful as Comminution '08. We will be putting a provisional programme together later this month, so it is still not too late to submit abstracts. Amanda has also been busy and MEI Online is on the move again, with new headlines and news items. She has sent out a newsletter today, slightly later than usual. Jon is back in UK now, and is in London at the moment for his girl-friend's 30th birthday. He's back in Cornwall on Sunday, so we should be back to full normality on Monday! If you are interested in the processing of gold, silver, PGM or nickel ores and concentrates, then Falmouth, Cornwall is the place to be next June. Precious Metals '10 and Nickel Processing '10 will run back to back at the Falmouth Beach Resort Hotel. Precious Metals '10 is currently sponsored by Maelgwyn Mineral Services, Newmont Mining and Barrick Gold. Nickel Processing '10 is sponsored by Xstrata Process Support. If you would like to present a paper at either conference, then the deadline for abstracts is the end of this month. It is reported today that more than 1700 scientists have agreed to sign a statement defending the "integrity and honesty" of global warming research, responding to a round robin request from the Met Office as a sign of how worried it is that emails stolen from the University of East Anglia are casting doubts on anthropogenic global warming (see my blog of 23rd November). This to me doesn't seem the best way of convincing people that the science is sound, and one of the scientists said that he felt under pressure to sign the circular or risk losing work! The Met Office also admitted that many of the signatories did not work on climate change! One scientist told The Times "The Met Office is a major employer of scientists and has long had a policy of only appointing and working with those who subscribe to their views on man-made global warming." Do thermometer readings "cut out the doubt"? An article in today's Times reports on yesterday's Climate Change debate in Copenhagen, and is headed "Back-to-basics measure cuts out the doubt". It reports that the data from the World Meteorological Organisation is a welcome return to basics. It does not rely on any of the 'proxy' measurements that are subject to criticism, but is based on the simplest, most direct measure of temperature- land and sea-based thermometers. You said: "During the 20th century the number of stations providing data must have fluctuated, and those situated in or near cities must have been influenced by the 'urban heating effect'".This is a good point. However, the inhomogeneities in the data sets are well known and accounted for. In addition, the UHI is well known and can be accounted for in climate records.We can measure C02 levels from proxy records too (including ice cores, plant stomata etc) and they also show a consistent rise with GHG emissions. So I am not at all sure how thermometer readings "cut out doubts". and maybe Stephan, you could clarify how "inhomogeneities in the data sets" are accounted for. You also stated in a comment on October 19th that "The input data to the models doesn't include average annual temperature. The models are developed from simple energy balance models. temperature is an output rather than input." Even more confusing! Life cycle assessments of the mining and mineral processing of iron ore, bauxite and copper concentrate have been carried out by workers at Australia's CSIRO and the results published in Journal of Cleaner Production. The work focussed on embodied energy and greenhouse gas emissions. The results showed that loading and hauling make the largest contributions to the total greenhouse gas emissions for the mining and processing of iron ore and bauxite. In the case of copper ore, the crushing and grinding steps make the largest contribution to the total greenhouse gas emissions for the production of copper concentrate. These results indicate that efforts to reduce the increased greenhouse gas emissions from mining and mineral processing, anticipated in the future as a result of falling ore grades and more finer-grained deposits, should focus on loading and hauling for iron ore and bauxite, while for copper ore the focus should be on grinding. There are a number of new and emerging technologies that could be expected to assist in this task, and these include high pressure grinding rolls and stirred mills for grinding, areas which will be explored in April's Comminution '10 conference in Cape Town. Emerging technologies to combat CO2 emissions is also one of the themes of Climate Change and the Minerals Industry '11. After over 4 weeks of fine dining in the Cape, it was back to the real world today, starting with an excellent bacon buttie and mug of tea at the West Cornwall Pasty shop on Platform 1 of London Paddington Station. We are back home in Falmouth now, and looking forward to an evening meal of beans on toast and catching up on a few missed episodes of Coronation Street! OK, sad, I know, but bliss, and this will be the first wine-free day for several weeks- also the first time we have seen TV for a while, apart from the tedious World Cup Draw from Cape Town on Friday night. Had texts from Amanda and Jon. Amanda returns tonight from a "tiring" week of conferencing in Spain, while Jon has been canoeing on the Orange River in Namibia, and crosses the border into South Africa tomorrow, returning to Famouth later in the week. Back to the grind tomorrow, and hopefully sorting out the programmes for the forthcoming conferences, Processing of Industrial Minerals, and Comminution. Very hot final day in Franschhoek. Barbara and I enjoyed yet another excellent lunch, this time at Cafe Bon Bon at La Petite Dauphine Guest Farm, before leaving for the airport. Hermanus- The Windsor Hotel (3). Adequate accommodation and very conveniently situated on the sea-front, within walking distance of the restaurants. Swellendam- The Coachman Guest House (5). Very relaxing overnight stop, with lovely gardens and pool, and good breakfast. Knysna- Milkwood Bay Guest House (2). Wonderfully situated on the lagoon, but disappointing amenities and breakfast. Main criticism is that it is GROSSLY over-priced, so we cannot recommend it. A better option is the adjacent Under Milk Wood cottages, where we have stayed twice previously, which are more basic, but are good value for money considering the location. Prince Albert- Dennehof Guest House (5). Wonderful Karoo character, and excellent breakfast. Matjiesfontein - Lord Milner Hotel (3). A must stop-over, but the faded elegance is fading very quickly. The pool was out of service, and judging by the colour of the water, has been for some time. Excellent Karoo lamb, however, at the evening dinner. Franschhoek- Erica's Guest House. Our 4th time here, and never disappoints. Paul and Rosemary very friendly and helpful hosts. Great place to relax by the lovely pool and gardens, and the main street of Franschhoek is only a short walk away. There can be very few restaurants in the world with a view like this one, at La Petite Ferme Wine Estate, Franschhoek. Today, over lunch at the restaurant, we bade farewell to our friends Judy, Mike and Jane, who fly back to the UK today. Barbara and I have one more night in Franschhoek before leaving for Cape Town airport tomorrow afternoon, and the long journey back to a very wet and cold Cornwall. Hope the blog followers have enjoyed our trip around the beautiful Western Cape. It's back to basics on Monday!! One of South Africa's most beautiful drives today, through Worcester to Franschhoek, via Du Toit's Pass. Our favourite Guest Houses on this grand tour are Prince Albert's Dennehof and Erica's, nestling under the mountains at Franschhoek. After a quick dip in the pool, we picnic-lunched under the trees at the nearby Mont Rochelle Wine Estate. Then back to Erica's to check email and the journal. Good to see that papers from Flotation '09 are now flowing in for the special issue, but apologies folks- I won't be dealing with them until next week, when we return to a very cold Cornwall. After an excellent breakfast at the Dennehof (left), and a leisurely morning in Prince Albert, we left for the Karoo and a stop-over at the quirky town of Matjiesfontein, a remnant of Victorian colonialism, and the faded elegance of the Lord Milner hotel. With well-preserved shops and post-office, this single street town resembles a film set and the railway station in front of the hotel serves the main line from Cape Town to Johannesburg. Today we travelled from Knysna to Prince Albert on one of my favourite South African drives, through the Outeniqua and Swartberg Passes. This was the 4th time that we have made this journey, the first being with the family in 1982, when I was a visiting lecturer at the University of Cape Town. The Swartberg Pass between Oudtshoorn and Prince Albert is a unique experience and a major challenge for our friends, who are not too happy with heights. An untarred road with precipitous hairpins, it offers some of the most spectacular scenery in the Cape. Arriving in the little town of Prince Albert, on the cusp between the Little and Great Karoo we stayed overnight at the Dennehof Guest House, a National Monument homestead.
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Welcome back to Orange, NJ! This 1950s Acme is now one of the five Super Supermarket locations in New Jersey. We saw a full tour in October 2017. However, there is one big change since then. A visit at the end of December 2017 showed the store with plenty of festive flags. Not sure what we're celebrating, exactly, but it's nice. And from the same visit, here's a slightly better picture than before of the 1950s Acme tower sign. The real change, which I saw only at the beginning of this May, is inside. The flooring, which was previously really awful, is now very nice. Some parts of the store were literally patched with duct tape and cardboard. As of May 4th, about 1/2 of the grocery aisles and the front-end had been redone. The back aisle, produce aisle, and first few grocery aisles still have the white vinyl tiles. The store, which is located at 53 S Jefferson St in Orange is also stocking an increasing number of organic and specialty products (reflecting the fact that there is significant new development along the train line, which goes directly to New York City), although the focus is still lower-end. Sure does. I'm assuming (and hoping) they'll do the whole store. I haven't been back for a while, so I'm not sure.
I'm a quiet shy guy with a desire to move out of my parents place. I don't really party or go out on nights out much anymore. I'm recently single and feel like Now is a good time to move on and get on with life.