input large_stringlengths 363 2.35k | output large_stringclasses 2 values |
|---|---|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cccc([N+](=O)[O-])c1CO
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(O)c1[N+](=O)[O-]
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CNC(=O)Oc1ccccc1OC(C)C
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1C
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(Cl)cc1Cl
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=c1oc2cc([N+](=O)[O-])ccc2c2ccccc12
Answer: (B)
Drug SMILES: CN(C)c1ccc(N=Nc2ccccc2C(=O)O)cc1
Answer: (B)
Drug SMILES: CCN(N=O)C(=N)N[N+](=O)[O-]
Answer: (B)
Drug SMILES: O=CC(Br)CBr
Answer: (B)
Drug SMILES: COc1cccc(N)c1
Answer: (B)
Drug SMILES: N#C[C@@H](O)c1ccccc1
Answer: (A)
Drug SMILES: Nc1cccc2c1Cc1ccccc1-2
Answer: (B)
Drug SMILES: CCNCC#CC(C)(C)OC(=O)C(O)(c1ccccc1)C1CCCCC1
Answer: (A)
Drug SMILES: C=Cc1ccc(O)c(OC)c1
Answer: (A)
Drug SMILES: COc1ccc2c(c1)C1CCCCC1C1OC21
Answer: (A)
Drug SMILES: Cc1cccc([N+](=O)[O-])c1C
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccccc1SSC(F)=C(Cl)Cl
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1nncc2ccccc12
Answer: (A)
Drug SMILES: O=Nc1[nH]cnc1-c1ccccc1
Answer: (B)
Drug SMILES: Nc1cccc(Cl)c1
Answer: (A)
Drug SMILES: CC(C)(c1ccccc1)c1ccc(O)cc1
Answer: (A)
Drug SMILES: C[C@@H](O)COC(C)(C)C
Answer: (B)
Drug SMILES: Cc1ccc2c(c1)-c1cc3ccccc3c3cc4ccccc4c-2c13
Answer: (B)
Drug SMILES: CCN(CCCO)N=O
Answer: (B)
Drug SMILES: CC(C)(c1ccc(OC[C@H]2CO2)cc1)c1ccc(OC[C@H]2CO2)cc1
Answer: (B)
Drug SMILES: CC(Br)C(Br)CCl
Answer: (B)
Drug SMILES: N#Cc1ccccc1[N+](=O)[O-]
Answer: (A)
Drug SMILES: CN(Cc1ccc(F)cc1)N=O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Clc1cccc(Cl)c1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1cc(I)c(O)c([N+](=O)[O-])c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: OCCOc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)OC(=O)COc1ccc(Cl)cc1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCCOC(=O)c1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)C(=O)Nc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COC12C(=COC(N)=O)c3c(O)c(N)c(C)c(O)c3N1CC1NC12
Answer: (B)
Drug SMILES: O=[N+]([O-])c1ccc([N+](=O)[O-])c(O)c1
Answer: (B)
Drug SMILES: Nc1c(O)cccc1C(=O)O
Answer: (A)
Drug SMILES: O=NN1CCCN(N=O)CC1
Answer: (B)
Drug SMILES: NNOS(=O)(=O)O
Answer: (B)
Drug SMILES: Oc1cc2c3ccccc3cc3ccc4cccc1c4c32
Answer: (B)
Drug SMILES: CCCCCCC(O)CC=CCCCCCCCC(=O)O
Answer: (A)
Drug SMILES: C[C@@H](CCN(C)C)N(C)C
Answer: (A)
Drug SMILES: O=C1CCC(=O)N1c1cc(Cl)cc(Cl)c1
Answer: (A)
Drug SMILES: CCc1c2ccccc2cc2c3c(ccc12)C(O)C(O)C1OC31
Answer: (B)
Drug SMILES: Nc1cc(Cl)c(N)c(Cl)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)Nc1cccc(C)c1
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc2c([N+](=O)[O-])cc3c([N+](=O)[O-])cccc3c2c1
Answer: (B)
Drug SMILES: c1ccc2c(c1)CCCC2
Answer: (A)
Drug SMILES: C1CCC2OCCOCCOCCOCCOC3CCCCC3OCCOCCOCCOCCOC2C1
Answer: (A)
Drug SMILES: C1=CC2C3C=CC(C3)C2C1
Answer: (A)
Drug SMILES: Nc1ccc2ccc3cc4ccccc4c4ccc1c2c34
Answer: (B)
Drug SMILES: CCC(O)CN
Answer: (A)
Drug SMILES: ClCc1cc2cccc3ccc4c5ccccc5cc1c4c32
Answer: (B)
Drug SMILES: Cc1c(N=[N+]([O-])c2cc([N+](=O)[O-])c(C)c([N+](=O)[O-])c2)cc([N+](=O)[O-])cc1[N+](=O)[O-]
Answer: (B)
Drug SMILES: CCCN(N=O)C(N)=O
Answer: (B)
Drug SMILES: Nc1cc(Cl)ccc1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1NO
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1c(C)c(Br)c(Br)c(Br)c1Br
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=CN(O)c1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cc([N+](=O)[O-])cc(Cl)c1O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(O)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=NN(O)c1ccccc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: c1ccc2c(c1)-c1cc3ccccc3c3cc4ccccc4c-2c13
Answer: (B)
Drug SMILES: CCCCNCC
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc2c(c1)Cc1cc([N+](=O)[O-])ccc1-2
Answer: (B)
Drug SMILES: c1ccc2cc3c(cc2c1)c1c(c2ccccc23)O1
Answer: (B)
Drug SMILES: NP(=O)(OCCC(=O)O)N(CCCl)CCCl
Answer: (B)
Drug SMILES: CSCCC(NC=O)C(=O)NC(Cc1ccccc1)C(=O)O
Answer: (A)
Drug SMILES: O=[N+]([O-])C1=Cc2cc3cc4ccccc4cc3c3cccc1c23
Answer: (B)
Drug SMILES: O=C1c2ccccc2C(=O)N1SC(Cl)(Cl)Cl
Answer: (B)
Drug SMILES: CCCCCCCCCCCCCC(=O)O[C@@H]1[C@H](C)[C@]2(O)[C@@H](C=C(CO)C[C@@]3(O)C(=O)C(C)=C[C@H]32)[C@H]2C(C)(C)[C@]21OC(C)=O
Answer: (A)
Drug SMILES: C[C@H]1C[C@@H](OC(=O)c2ccccc2O)CC(C)(C)C1
Answer: (A)
Drug SMILES: CCOc1ccc(N)cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1c2ccccc2nc2ccc([N+](=O)[O-])cc12
Answer: (B)
Drug SMILES: CN(C)NC(=O)CCC(=O)O
Answer: (A)
Drug SMILES: OC1c2cc3ccc4ccccc4c3cc2C2OC2C1O
Answer: (B)
Drug SMILES: O=S(c1cc(Cl)cc(Cl)c1O)c1cc(Cl)cc(Cl)c1O
Answer: (B)
Drug SMILES: Oc1ccc2ccc3c4c(cc5ccc1c2c53)C(O)C(O)C=C4
Answer: (B)
Drug SMILES: CC12OOC1(C)c1ccccc1O2
Answer: (B)
Drug SMILES: O=C(O)/C=C/c1ccccc1[N+](=O)[O-]
Answer: (A)
Drug SMILES: NN(c1ccccc1)c1ccccc1
Answer: (A)
Drug SMILES: O=C1c2ccccc2-c2ccc3c4ccc5c6c(ccc(c7ccc1c2c73)c64)C(=O)c1ccccc1-5
Answer: (B)
Drug SMILES: C=CCC1C(=O)CC(OC(=O)C2C(C=C(C)C)C2(C)C)=C1C
Answer: (B)
Drug SMILES: CON(C)C(=O)Nc1ccc(Br)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc([N+](=O)[O-])cc1Cl
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cccc(O)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: C[C@@H](O)c1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=S)(OC)Oc1ccc([N+](=O)[O-])cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOS(=O)(=O)c1ccccc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1
Answer: (A)
Drug SMILES: CC(C)(C#N)C(C)(C)C#N
Answer: (A)
Drug SMILES: CCCC(=O)OCCC(C)C
Answer: (A)
Drug SMILES: C=C(C)C1CCC(=C)C2C3=C(CC(C)(O)C3=O)C(=O)C(C)=CC12
Answer: (A)
Drug SMILES: CC1CN(N=O)CC(C)O1
Answer: (B)
Drug SMILES: NC(CCC(=O)NC(CSC(=O)NCCO)C(=O)NCC(=O)O)C(=O)O
Answer: (A)
Drug SMILES: [N-]=[N+]=Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1
Answer: (B)
Drug SMILES: O=[N+]([O-])c1cccc2nc3c([N+](=O)[O-])cccc3nc12
Answer: (A)
Drug SMILES: Cn1c(N)nc2c3ccc(O)nc3ccc21
Answer: (B)
Drug SMILES: O=C1c2cc(O)cc(O)c2C(=O)c2c1cc1c(c2O)[C@@H]2C=CO[C@@H]2O1
Answer: (B)
Drug SMILES: O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COC(C)CCO
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc2ccc3cccc4cc(O)c1c2c34
Answer: (B)
Drug SMILES: O=C1CCCO1
Answer: (A)
Drug SMILES: COc1cc2c(c3oc4cccc(O)c4c(=O)c13)C1C=COC1O2
Answer: (B)
Drug SMILES: OC1=C(O)C23CCCCC2(O3)c2cc3ccc4ccccc4c3nc21
Answer: (A)
Drug SMILES: COP(=S)(OC)Oc1ccc(N=O)c(C)c1
Answer: (B)
Drug SMILES: CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1
Answer: (A)
Drug SMILES: CC(OP(C)(=O)Cl)C(C)(C)C
Answer: (A)
Drug SMILES: Cc1cnc2c(C)cc3c(nc(N)n3C)c2n1
Answer: (B)
Drug SMILES: CCCCOP(=O)(OCCCC)OCCCC
Answer: (A)
Drug SMILES: CCO[P@](=S)(CC)Sc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc([N+](=O)[O-])c(N)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc([N+](=O)[O-])c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccccc1C(=O)O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(N=O)C(=O)NC1C(O)OC(CO)C(O)C1O
Answer: (B)
Drug SMILES: Cc1ccc2cc3c4c(ccc3c3c2c1CC3)[C@@H](O)[C@H](O)C=C4
Answer: (B)
Drug SMILES: Cc1c(C)c([N+](=O)[O-])c(C(C)(C)C)c([N+](=O)[O-])c1C
Answer: (A)
Drug SMILES: O=S(=O)(O)Oc1ccc2ccc3cc4ccccc4c4ccc1c2c34
Answer: (B)
Drug SMILES: O=Nn1cnc(CC(=O)NO)c1
Answer: (B)
Drug SMILES: N=C(N)c1ccc2c(N)c(C(=N)N)[nH]c2c1
Answer: (A)
Drug SMILES: COC(=O)c1ccc(O)cc1
Answer: (A)
Drug SMILES: O=C(O)C1=CC(O)C(O)C(O)C1
Answer: (A)
Drug SMILES: CC1CC2(C)C(CCC3C4CCC(O)C4(C)CCC32)CC1=O
Answer: (A)
Drug SMILES: O=C1c2ccccc2C(=O)c2c1ccc(O)c2O
Answer: (B)
Drug SMILES: Brc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOP(=S)(CC)Sc1ccccc1
Answer: (A)
Drug SMILES: COc1ccc(NC(=O)c2csc([N+](=O)[O-])c2)cc1
Answer: (B)
Drug SMILES: COc1cc2c(c3ccc4ccccc4c13)CCC2=O
Answer: (B)
Drug SMILES: C(CCOC[C@H]1CO1)COC[C@H]1CO1
Answer: (B)
Drug SMILES: Nc1ccc(/C=C/C(=O)O)cc1
Answer: (A)
Drug SMILES: c1cc(-c2cc3ccc(C4=NCCN4)cc3[nH]2)ccc1C1=NCCN1
Answer: (A)
Drug SMILES: S=c1scc(-c2ccccc2)s1
Answer: (A)
Drug SMILES: Cc1ccc(N=NN(C)C)cc1
Answer: (B)
Drug SMILES: CC(=O)c1cccc([N+](=O)[O-])c1
Answer: (B)
Drug SMILES: CCCCCO
Answer: (A)
Drug SMILES: Cc1cc(N)c(S(=O)(=O)O)cc1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(O)c(N)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)=O
Answer: (A)
Drug SMILES: CC(Oc1ccc(Cl)cc1Cl)C(=O)O
Answer: (A)
Drug SMILES: NC1CCC(CC2CCC(N)CC2)CC1
Answer: (A)
Drug SMILES: CN(C)NC(=O)CCC(=O)O
Answer: (A)
Drug SMILES: CC(=O)Nc1ccc2cccnc2c1
Answer: (B)
Drug SMILES: Cc1ccccc1C(N)=O
Answer: (A)
Drug SMILES: c1cnc2c(c1)ccc1c3cccnc3ccc12
Answer: (B)
Drug SMILES: O=C1c2ccc(O)cc2C(=O)c2ccc(O)cc21
Answer: (A)
Drug SMILES: N#C/C=C\C#N
Answer: (A)
Drug SMILES: CCCN(CCC)CCC
Answer: (A)
Drug SMILES: O=C/C=C/c1ccccc1[N+](=O)[O-]
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccc(I)c([N+](=O)[O-])c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cccc(O)c1N
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1c(N)ccc(N)c1C
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)c1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCCCCCCCCCOC(=O)c1ccccc1C(=O)OCCCCCCCCCCCCC
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1OCC(=O)O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(CN=[N+]=[N-])c1ccccc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(N)c(C)c([N+](=O)[O-])c1N
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(C)C(=O)Nc1ccc(Cl)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccccc1C=O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1cc(F)ccc1[N+](=O)[O-]
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCC(=O)OCc1cccc([N+](=O)[O-])c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)(C)C(Br)C(=O)Nc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1O[C@H](C)C(=O)O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: OC1C=Cc2ccc3nc4ccc5ccccc5c4cc3c2C1O
Answer: (B)
Drug SMILES: O=C(C(F)(F)F)C(F)(F)F
Answer: (A)
Drug SMILES: CC(=O)N(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccc(Oc2ccc(Cl)cc2)cc1
Answer: (B)
Drug SMILES: C1=C[C@H]2O[C@H]2c2cc3ccc4cccc5ccc(c21)c3c45
Answer: (B)
Drug SMILES: CCCCOC(=O)CCCCCCCCC(=O)OCCCC
Answer: (A)
Drug SMILES: CC(=O)OC1C(O)C2OC3C=C(C)C(=O)C(O)C3(CO)C1(C)C21CO1
Answer: (A)
Drug SMILES: COP(=S)(OC)Oc1ccc(SC)c(C)c1
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc2c(c1)Oc1ccccc1O2
Answer: (B)
Drug SMILES: O=C(CCl)c1ccc(Cl)cc1Cl
Answer: (B)
Drug SMILES: CN(C)C(=S)N(C)C
Answer: (A)
Drug SMILES: Cc1cc([N+](=O)[O-])ccc1[N+](=O)[O-]
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cccc(NO)c1C
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Oc1cc(Cl)c(Cl)cc1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: C[C@H]1CN(N=O)C[C@@H](C)N1N=O
Answer: (B)
Drug SMILES: CNc1ccc2ccc3ccc(O)cc3c2c1
Answer: (B)
Drug SMILES: Nc1ccc(S(=O)(=O)Nc2cnc3c(Cl)cccc3n2)cc1
Answer: (A)
Drug SMILES: O=C1OCC(C(Br)Br)=C1Cl
Answer: (B)
Drug SMILES: CC(=O)Nc1ccc(C)c(N=Nc2cc(NC(C)=O)ccc2C)c1
Answer: (A)
Drug SMILES: CCOCOCC
Answer: (A)
Drug SMILES: CC(=O)N(C)N=O
Answer: (B)
Drug SMILES: CCC(Cl)CC(Cl)CC(C)Cl
Answer: (A)
Drug SMILES: CCOP(=O)(C#N)N(C)C
Answer: (A)
Drug SMILES: COc1c(N)cc(C)c(N)c1C
Answer: (A)
Drug SMILES: Nc1ccccc1C(F)(F)F
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)c1ccc(Cl)c(Cl)c1Cl
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1cc(N)ccc1NC(C)=O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)Oc1ccc(CO)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Clc1ccnc2ccccc12
Answer: (B)
Drug SMILES: COP(=O)(OC)OC
Answer: (B)
Drug SMILES: Cc1cccc(NO)c1
Answer: (B)
Drug SMILES: CC(C)C[C@@H](C)Nc1ccc(Nc2ccccc2)cc1
Answer: (A)
Drug SMILES: O=C1c2cc([N+](=O)[O-])ccc2-c2c1cc([N+](=O)[O-])cc2[N+](=O)[O-]
Answer: (B)
Drug SMILES: COCCOC(=O)c1ccccc1C(=O)OCCOC
Answer: (B)
Drug SMILES: O=Cc1ccc(Cl)cc1Cl
Answer: (A)
Drug SMILES: NC(CSC(F)(F)C(F)(F)C(F)F)C(=O)O
Answer: (A)
Drug SMILES: CCc1cccc(NC(=O)c2csc([N+](=O)[O-])c2)c1
Answer: (B)
Drug SMILES: CC#N
Answer: (A)
Drug SMILES: Cc1ccccc1N
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)Cc1ccc([N+](=O)[O-])cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)c1cc(NC(N)=O)ccc1OC[C@H](O)CNC(C)(C)C
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOP(=O)(NC(C)CC)Oc1cc(C)ccc1[N+](=O)[O-]
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: NCCc1cc(O)c(O)cc1O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)COc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1cccc2cccnc12
Answer: (B)
Drug SMILES: O=C1c2ccccc2-c2c1c1ccccc1c(=O)n2CCNCCO
Answer: (A)
Drug SMILES: [N-]=[N+]=Nc1ccc2c(Nc3ccc(NS(=O)(=O)CCCN)cc3)c3ccc(N=[N+]=[N-])cc3nc2c1
Answer: (B)
Drug SMILES: Cc1nc(O)c(C#N)cc1-c1ccncc1
Answer: (A)
Drug SMILES: Cl/C=C\CCl
Answer: (B)
Drug SMILES: CS(=N)(=O)CCC(N)C(=O)O
Answer: (A)
Drug SMILES: CC(O)c1ccc2ccc3cccc4ccc1c2c34
Answer: (B)
Drug SMILES: CC(O)C(=O)NCCO
Answer: (B)
Drug SMILES: O=C1C(c2[nH]c3ccccc3c2O)=Nc2ccccc21
Answer: (B)
Drug SMILES: C=C/C=C\C
Answer: (A)
Drug SMILES: CCNc1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccccc1Br
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(NO)c1ccccc1O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1c2ccccc2c(CBr)c2c1ccc1ccccc12
Answer: (B)
Drug SMILES: O=[N+]([O-])c1ccc2c(c1)Cc1cc(O)ccc1-2
Answer: (B)
Drug SMILES: O=[N+]([O-])c1ccc(-c2nc(NCCO)c3ccccc3n2)s1
Answer: (B)
Drug SMILES: O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C(F)(F)F
Answer: (B)
Drug SMILES: COCC1CN(c2ccc3nc(C(O)CCC#N)sc3c2)C(=O)O1
Answer: (A)
Drug SMILES: C=CCCCCCCCCCCCC
Answer: (A)
Drug SMILES: Cn1c(CC(=O)OCCCl)c(C(=O)O)c2ccccc21
Answer: (B)
Drug SMILES: CC(=O)NBr
Answer: (A)
Drug SMILES: O=C(O)c1occ(-c2ccccc2)c1-c1ccccc1
Answer: (A)
Drug SMILES: C=CC(OC(C)=O)c1ccc(OC)cc1
Answer: (B)
Drug SMILES: Nc1c(O)cccc1[N+](=O)[O-]
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1c(N)cc(C)c(N)c1C
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1ccc(CCl)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COC(=O)c1ccccc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(Cc1cccc(C(F)(F)F)c1)N=O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCOc1ccc(N=O)cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(S(=O)(=O)O)c(N)cc1Cl
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCc1cc(O)cc(O)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=Cc1cccc(Cl)c1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOc1ccc(NC(N)=O)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(Sc2ccc(N)cc2)cc1
Answer: (B)
Drug SMILES: O=C1[C@@H]2CC=CC[C@H]2C(=O)N1SC(Cl)(Cl)Cl
Answer: (B)
Drug SMILES: CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1
Answer: (A)
Drug SMILES: CCCCOC(=O)CCC
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc2ccc3cc4c(c5ccc1c2c35)C=CC(O)C4O
Answer: (B)
Drug SMILES: C[C@@H]1CNC[C@@H](C)O1
Answer: (B)
Drug SMILES: CCCCN(COC(C)=O)N=O
Answer: (B)
Drug SMILES: CC(C)(N=O)[N+](=O)[O-]
Answer: (B)
Drug SMILES: Nc1ccccc1SCCSc1ccccc1N
Answer: (B)
Drug SMILES: COC(=O)c1ccc([N+](=O)[O-])c2c(NCCCN(C)C)c3ccccc3nc12
Answer: (B)
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1C(=O)O
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(CO)c([N+](=O)[O-])c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=S)(OC)Oc1ccc(N)c(C)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=CN(O)c1ccc(Cl)c(Cl)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1ccc(C=O)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc(C=O)cc1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=O)(OC)O/C(=C\Cl)c1cc(Cl)c(Cl)cc1Cl
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#[N+]c1ccc([N+](=O)[O-])cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCN(CC)CC#CC(C)(C)OC(=O)C(O)(c1ccccc1)C1CCCCC1
Answer: (A)
Drug SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)=O)C1c1ccccc1[N+](=O)[O-]
Answer: (A)
Drug SMILES: CC(=O)C1(c2ccccc2)CCNCC1
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccccc1SSC(F)=C(Cl)Cl
Answer: (B)
Drug SMILES: CCCCCCCCCCCl
Answer: (A)
Drug SMILES: CC(Cl)Cl
Answer: (A)
Drug SMILES: C[C@@H](Cl)CCl
Answer: (B)
Drug SMILES: Cc1c(C(C)C)c(=O)n(-c2ccccc2)n1C
Answer: (A)
Drug SMILES: O=[N+]([O-])c1ccc(CCl)cc1
Answer: (B)
Drug SMILES: OCCNc1ccc(N=Nc2ccc(N(CCO)CCO)cc2)cc1
Answer: (A)
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(S(=O)(=O)O)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1ccc(O)c(C(C)(C)C)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cc2ccc3cc([N+](=O)[O-])cc4ccc(c1)c2c34
Answer: (B)
Drug SMILES: CC(C)(Oc1ccc(C2CC2(Cl)Cl)cc1)C(=O)O
Answer: (A)
Drug SMILES: ClC(Cl)(Cl)Cl
Answer: (A)
Drug SMILES: FC(C(F)(F)F)C(F)(F)F
Answer: (A)
Drug SMILES: CC12CCC=C(C=O)C1(C=O)C2
Answer: (B)
Drug SMILES: OCCNc1ccc(N=Nc2ccc(NCCO)cc2)cc1
Answer: (B)
Drug SMILES: CCC=O
Answer: (A)
Drug SMILES: c1ccc(-c2cccnc2)nc1
Answer: (B)
Drug SMILES: N#[N+]c1cccc2c1C(=O)c1ccccc1C2=O
Answer: (B)
Drug SMILES: Cc1cc(O)c2c(c1O)C(=O)c1c(O)ccc(O)c1C2=O
Answer: (B)
Drug SMILES: O=C(O)Cc1ccc(O)c(O)c1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1ccccc1O
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1cccc(CC)c1NC(=O)CO
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN[N+](=O)[O-]
Answer: (A)
Drug SMILES: O=c1c(O)c(-c2ccc(OCCO)c(OCCO)c2)oc2cc(OCCO)cc(O)c12
Answer: (A)
Drug SMILES: O=C1CCC(=O)N1O
Answer: (A)
Drug SMILES: Cn1ccnc1S
Answer: (A)
Drug SMILES: COc1c2ccc(O)cc2nc2occc12
Answer: (A)
Drug SMILES: CC=C(C=C(C)C=C(C)C=CC=C(C)C(=O)C12OC1C(O)(CCO)NC2=O)C(=O)OC
Answer: (B)
Drug SMILES: C=Cc1cccnc1
Answer: (A)
Drug SMILES: Cc1c2ccccc2c2ccc3cccc4ccc1c2c43
Answer: (B)
Drug SMILES: CCNc1snc2ccccc12
Answer: (A)
Drug SMILES: COc1ccc(CNCC(O)COc2ccc3nc(O)ccc3c2)cc1OC
Answer: (A)
Drug SMILES: O=C(CNC(=O)c1ccccc1)NO
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1ccccc1C#N
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)C(=O)N(O)c1ccc(Cl)cc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)NNc1ccccc1
Answer: | B |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)COC(=O)c1ccccc1N
Answer: (A)
Drug SMILES: CNC(=O)N(c1ccccc1)c1ccccc1
Answer: (A)
Drug SMILES: CCc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O
Answer: (A)
Drug SMILES: Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1
Answer: (B)
Drug SMILES: O=[N+]([O-])c1ccc2ccc3c4c(cc5ccc1c2c53)C=C[C@H](O)[C@H]4O
Answer: (B)
Drug SMILES: C=C(C#N)C(=O)OCC
Answer: (A)
Drug SMILES: C=C=O
Answer: (B)
Drug SMILES: CCN(CC)C(=O)Cc1ccccc1
Answer: (A)
Drug SMILES: COC1=CC(=O)c2c(nc(C)c3c4c[nH]ccc-4nc23)C1=O
Answer: (B)
Drug SMILES: OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O
Answer: (A)
Drug SMILES: O=C(O)CCC(=O)Nc1cc(Cl)cc(Cl)c1
Answer: | A |
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1/N=C/N(C)C
Answer: | A |
End of preview. Expand
in Data Studio
README.md exists but content is empty.
- Downloads last month
- 6