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Psychophysiological research integrating heart rate variability (HRV) has increased during the last two decades, particularly given the fact that HRV is able to index cardiac vagal tone. Cardiac vagal tone, which represents the contribution of the parasympathetic nervous system to cardiac regulation, is acknowledged to... | literature_review |
Abstract We have established four lines of monoclonal antibodies against human low-density lipoproteins (LDL) that, mixed in equal proportions, can precipitate LDL in gel and so can be used for apolipoprotein (apo) B determination in plasma. One monoclonal antibody (clone A), with a relatively low binding affinity to L... | research_paper |
Summary This article aims to design an optimal interval observer for discrete linear time‐invariant systems. Particularly, the proposed design method first transforms the interval observer into a zonotopic set‐valued observer by establishing an explicit mathematical relationship between the interval observer and the zo... | research_paper |
Background Depression is one of the leading causes of disability worldwide. Internet- and computer-based interventions (IBIs) have been shown to provide effective, scalable forms of treatment. More than 100 controlled trials and a growing number of meta-analyses published over the past 30 years have demonstrated the ef... | literature_review |
Background Tick-borne encephalitis (TBE) is the most important tick-borne viral disease in Eurasia and causes disease in humans and in a number of animals, among them dogs and horses. There is still no good correlation between tick numbers, weather conditions and human cases. There is the hypothesis that co-feeding due... | research_paper |
Peptides confer interesting properties to materials, supramolecular assemblies and to lipid membranes and are used in analytical devices or within delivery vehicles. Their relative ease of production combined with a high degree of versatility make them attractive candidates to design new such products. Here, we review ... | research_paper |
The hallmark of nucleophilic phosphine catalysis is the initial nucleophilic addition of a phosphine to an electrophilic starting material, producing a reactive zwitterionic intermediate, generally under mild conditions. In this Review, we classify nucleophilic phosphine catalysis reactions in terms of their electrophi... | literature_review |
Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development in the mouse embryo. We report here that, in the adult mouse, Bcl11a is expressed in most hematopoietic cells and is highly enriched in B cells, early T cell progenitor... | research_paper |
It has previously been demonstrated that there are two distinct mechanisms for genetic resistance to human immunodeficiency virus type 1 (HIV-1) conferred by the CCR5Δ32 gene: the loss of wild-type CCR5 surface expression and the generation of CCR5Δ32 protein, which interacts with CXCR4. To analyse the protective effec... | research_paper |
To explain the observations in the context of chlamydial infection and trachoma we propose a two-stage model of response and disease that balances the cytolytic response of KIR expressing NK cells with the ability to secrete interferon gamma, a combination that may cause pathology. The data presented indicate that HLA-... | research_paper |
Supplemental material, Supplementary_table_1 for Primary Clear Cell Adenocarcinoma of the Vulva: A Case Study With Mutation Analysis and Literature Review by Naoki Kojima, Hiroshi Yoshida, Takashi Uehara, Takeshi Ushigusa, Yuka Asami, Kouya Shiraishi and Tomoyasu Kato in International Journal of Surgical Pathology | literature_review |
Abstract The obligate intracellular bacterial pathogen Chlamydia pneumoniae (Cp) is responsible for a range of human diseases, including acute respiratory infection. Although experimental intratracheal infection with Cp results in a massive recruitment of neutrophil granulocytes (polymorphonuclear neutrophils (PMN)), t... | research_paper |
We have examined the functional consequences of ADP-ribosyltransferase modification of Ras by the exoenzyme S (ExoS) protein of Pseudomonas aeruginosa. ExoS has been shown previously to ADP-ribosylate a number of proteins, including members of the Ras superfamily, which play an essential role in the processes of cell p... | research_paper |
The increase in duration, severity, and frequency of extreme heat will have a profound detrimental impact on human health, as extreme heat is the deadliest weather-related event around the world. At the same time, the population of older (>65 yr) adults is rapidly expanding. The exaggerated heat, coupled with an agi... | literature_review |
Recent particle-in-cell simulations of the stimulated Brillouin backscattering (SBBS) of electromagnetic radiation have shown that even at sub-relativistic intensities ( I λ 2 = 10 16 Wμm 2 /cm 2 ) non-drifting solitary waves, “solitons” for short, are easily produced, and remain almost unchanged all along the simulati... | research_paper |
Abstract This review pertains the current knowledge concerned with the application of SCP in human and animal nutrition. General factors limiting the utilization of microbial proteins in human nutrition, such as toxicological barriers, nutritive value and functional properties, are discussed. Special attention is paid ... | research_paper |
Oleate, linoleate, linolenate, arachidonate and eicosapentaenoate, but not myristate, palmitate and stearate, stimulated glycogen phosphorylase activity by 2-8-fold when added to cultured rat hepatocytes. Addition of BSA or Ca2- to the incubation medium decreased the stimulating effects of the unsaturated fatty acids. ... | research_paper |
Trk receptors are a family of three receptor tyrosine kinases, each of which can be activated by one or more of four neurotrophins-nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophins 3 and 4 (NT3 and NT4). Neurotrophin signaling through these receptors regulates cell survival, prolife... | literature_review |
Background: Enamel matrix derivative (EMD) is commonly used in periodontal therapy. The aim of this systematic review is to give an updated answer to the question of whether the additional use of EMD in periodontal therapy is more effective compared with a control or other regenerative procedures. Methods: A literature... | literature_review |
Abstract Motivation Compound structure identification is using increasingly more sophisticated computational tools, among which machine learning tools are a recent addition that quickly gains in importance. These tools, of which the method titled Compound Structure Identification:Input Output Kernel Regression (CSI:IOK... | research_paper |
The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of randomised controlled trials that reported the effects of an intervention tha... | literature_review |
The Hippo pathway has emerged as a conserved signaling pathway that is essential for the proper regulation of organ growth in Drosophila and vertebrates. Although the mechanisms of signal transduction of the core kinases Hippo/Mst and Warts/Lats are relatively well understood, less is known about the upstream inputs of... | literature_review |
We have analyzed the configuration of the immunoglobulin heavy (IgH) chain gene and the T cell receptor (TCR) chain (beta, gamma, and delta) genes in a group of 22 leukemia patients with the Philadelphia (Ph) chromosome. The group consisted of 14 patients with chronic myelogenous leukemia in blast crisis (CML-BC) and e... | research_paper |
As the most commonly occurring cancer in women worldwide, breast cancer poses a formidable public health challenge on a global scale. Breast cancer consists of a group of biologically and molecularly heterogeneous diseases originated from the breast. While the risk factors associated with this cancer varies with respec... | literature_review |
BACKGROUND: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncofetal protein present on many cancers. Zilovertamab vedotin (ZV) is an antibody–drug conjugate comprising a monoclonal antibody recognizing extracellular ROR1, a cleavable linker, and the anti-microtubule cytotoxin monomethyl auristatin E. MET... | research_paper |
Bacterial vaginosis (BV) is one of the most common infections in women of reproductive age.Clinical studies have shown an association among BV and abnormal pregnancy, pelvic inflammatory disease and increased risk of sexually transmitted infections, including HIV.This disorder was first described in 1914 by Curtis as a... | research_paper |
While the stepped wedge design offers a number of opportunities for use in future evaluations, a more consistent approach to reporting and data analysis is required. | literature_review |
The case of a 60-year-old man with acral persistent papular mucinosis (APPM), thought to represent a new distinctive form of dermal mucinosis not associated with systemic diseases, is reported. The patient had a 4-year history of multiple small papular lesions on the distal forearms, wrists and back of the hands. Histo... | research_paper |
Abstract Murine T cells adoptively transferred into syngeneic lymphopenic recipients undergo proliferation. Despite continued cell division, this lymphopenia-induced or homeostatic proliferation of a limited number of transferred T cells does not fill the T cell compartment. The continued expansion of the transferred T... | research_paper |
Advanced energy conversion and storage (ECS) devices (including fuel cells, photoelectrochemical water splitting cells, solar cells, Li-ion batteries and supercapacitors) are expected to play a major role in the development of sustainable technologies that alleviate the energy and environmental challenges we are curren... | literature_review |
Abstract The interaction of human anaphylatoxin C4a with the guinea pig (gp) and human (hu) C3a receptors (C3aR) was analyzed using human rC4a, which exhibited C4a-specific activity on guinea pig platelets. A gpC3aR of 475 residues with a large second extracellular loop and a peptide sequence ∼60% identical to the huC3... | research_paper |
Fig. 3. Collection localities for specimens of Brassomys albidens. Numbers key to localities described in the gazetteer where specimens are also identified by museum initials and catalog numbers. | literature_review |
Introduction Monoterpene perillyl alcohol (POH) is cytotoxic to temozolomide-resistant glioma cells, regardless of its O6-methylguanine-methyltransferase (MGMT) promoter methylation status. Moreover, adherence to a ketogenic diet (KD) produced successful outcomes in preclinical and clinical studies in the glioma settin... | literature_review |
Summary A double‐blind crossover study has compared intra‐nasal sodium cromoglycate (SCG) with beclomethasone dipropionate (BDP), and both drugs with placebo, in fifty‐two chronic perennial rhinitis patients, BDP was significantly more effective in relieving symptoms than SCG (76.9% and 50% of the patients improved res... | research_paper |
Purpose: The study aimed to provide an overview of tomato loss during road transportation with specific interest in the causes of the postharvest loss, postharvest loss mitigation measures, as well as research focus and trends over the past few decades. Findings: Transport conditions significantly affect tomato quality... | literature_review |
Since the 1950s, replacement of immunoglobulin G using human immunoglobulin has been the standard treatment for primary immunodeficiency diseases with defects in antibody production. These patients suffer from recurrent and severe infections, which cause lung damage and shorten their life span. Immunoglobulins given in... | research_paper |
Recombinant immunotoxins: In the 1990s, advances in recombinant DNA techniques enabled the development of singlechain recombinant immunotoxins.DNA sequences encoding only the antigen-binding site of the antibody (the Fv portion) were fused to DNA sequences encoding PE38, the truncated form of PE.These single-chain reco... | research_paper |
Traditionally, measurement of the acute toxicity of pesticides to beneficial arthropods has relied largely on the determination of an acute median lethal dose or concentration. However, the estimated lethal dose during acute toxicity tests may only be a partial measure of the deleterious effects. In addition to direct ... | literature_review |
Traumatic anterior instability of the shoulder is commonly treated with the Latarjet procedure, which involves transfer of the coracoid process with a conjoint tendon to the anterior aspect of the glenoid. The two most common techniques of the Latarjet are the classical and congruent arc techniques. The aim of this stu... | research_paper |
Weil-Felix test is not a very sensitive test in diagnosis of scrub typhus but due to of lack of availability of definitive tests in India it canbe a useful tool when used and interpreted in the correct clinical context. | research_paper |
Androgen receptor (AR) is a member of the steroid hormone receptor family of molecules. AR primarily is responsible for mediating the physiologic effects of androgens by binding to specific DNA sequences that influence transcription of androgen-responsive genes. The three-dimensional structure of the AR ligand-binding ... | literature_review |
Anatomical and physiological studies in animals, as well as functional imaging studies in humans have shown that multiple cortical areas are activated by painful stimuli. The view that pain is perceived only as a result of thalamic processing has, therefore, been abandoned, and has been replaced by the question of what... | literature_review |
Abstract High‐affinity antibodies are produced during multiple processes in germinal centres (GCs), where follicular helper T (Tfh) cells interact closely with B cells to support B‐cell survival, differentiation and proliferation. Recent studies have revealed that a specialised subset of regulatory T cells, follicular ... | research_paper |
Dengue is a spectrum of disease caused by four serotypes of the most prevalent arthropod-borne virus affecting humans today, and its incidence has increased dramatically in the past 50 years. Due in part to population growth and uncontrolled urbanization in tropical and subtropical countries, breeding sites for the mos... | literature_review |
Our findings suggest that geographic location plays a limited role in the reasons for the large variability of ADHD/HD prevalence estimates worldwide. Instead, this variability seems to be explained primarily by the methodological characteristics of studies. | literature_review |
Abstract The protein tyrosine kinase p56lck is critical for the generation of mature thymocytes in adult mice. However its requirement during the maturation of thymocytes from the fetal to the adult stage has not been clearly defined. We analyzed prenatal and postnatal thymocyte maturation in mice deficient for p56lck ... | research_paper |
This systematic review indicated higher validity of steps, few studies on distance and physical activity, and lower validity for energy expenditure and sleep. The evidence reviewed indicated high interdevice reliability for steps, distance, energy expenditure, and sleep for certain Fitbit models. As new activity tracke... | literature_review |
Background: Immune checkpoint inhibitors (ICIs) have shown promising prospects in locally advanced, resectable gastric or gastroesophageal junction adenocarcinoma (GC/GEJC) immunotherapy, but their efficacy in neoadjuvant settings remains unclear. This study aimed to assess the efficacy and safety of integrating progra... | literature_review |
Abstract Immunostimulatory sequence (ISS) DNA containing unmethylated CpG dinucleotides stimulate NK and APC to secrete proinflammatory cytokines, including IFN-αβ and -γ, TNF-α, and IL-6 and -12, and to express costimulatory surface molecules such as CD40, B7-1, and B7-2. Although ISS DNA has little direct effect on T... | research_paper |
Malnutrition among community-dwelling older adults (OAs) is prevalent, particularly in groups using healthcare services. Malnutrition burdens health, social, and aged-care systems in terms of expenses for hospital admissions and care in nursing homes and home care settings. Effective management requires early identific... | literature_review |
A previous study of infection and morbidity in 400 women attending for termination of pregnancy (TOP) had shown that 32 (8%) harboured cervical Chlamydia trachomatis and 112 (28%) had anaerobic (bacterial) vaginosis (AV). Fifty-three per cent of the women with preoperative C. trachomatis had AV. Thirty of the 32 women ... | research_paper |
The immune system has evolved to respond not only to pathogens, but also to signals released from dying cells. Cell death through necrosis induces inflammation, whereas apoptotic cell death provides an important signal for tolerance induction. High mobility group box 1 (HMGB1) is a DNA-binding nuclear protein, released... | literature_review |
Background Despite increases in the incidence of coagulopathy-related soft-tissue hematoma (CRSH), the relationship between computed tomography (CT) features and clinical severity remains unclear. Purpose To retrospectively evaluate the correlation between CT findings and clinical outcomes in CRSH. Material and Methods... | research_paper |
Abstract:- Today in Indian industries total productive maintenance (TPM) has made significant impact on the managers, engineers, technicians and workers. Either with direct involvement in TPM implementation process or due to indirect awareness from employees of other nearby industries who have adopted or planned to ado... | literature_review |
The study examines the integration of emerging technologies into anatomy education and focuses on the impact on learning results and student involvement. It uses a comprehensive literature search to identify technologies such as virtual reality, three-dimensional printing of anatomical models, augmented reality, artifi... | literature_review |
OBJECTIVE: To assess the effect of preoperative dexamethasone on the occurrence of postoperative atrial fibrillation. METHODS: Random controlled trails were gathered though searches of PubMed (1966 - 2009.11), EMBASE (1974 - 2009.11), Cochrane Library (issue 4, 2009), Chinese Biomedical Literature Database (1978 - 2009... | literature_review |
OBJECTIVES: To estimate the prevalence of normal endometrial cells (NECs) and the proportion of NECs associated with significant endometrial pathology in conventional and liquid-based cytology (LBC) cervical smears; and to assess the association between NECs and clinical symptoms in women with endometrial hyperplasia o... | literature_review |
To date, the scientific literature has documented, primarily, successful methods and techniques of treatment involving vertical extrusion. The purpose of this article is to review the literature and report on a case that demonstrates the multidisciplinary approach required to successfully manage a reversible complicati... | literature_review |
This article reviews and discusses the empirical literature on interorganizational networks at the network level of analysis, or what is sometimes referred to as “whole” networks. An overview of the distinction between egocentric and network-level research is first introduced. Then, a review of the modest literature on... | literature_review |
Hyponatremia is defined as a decrease in the serum sodium concentration to a level below 136 mmol per liter. Whereas hypernatremia always denotes hypertonicity, hyponatremia can be associated with low, normal, or high tonicity.1,2 Effective osmolality or tonicity refers to the contribution to osmolality of solutes, suc... | literature_review |
Although a humanized CCR4 antibody (mogamulizumab) was reported to be effective for refractory adult T-cell leukemia-lymphoma (ATL), several reports regarding the use of mogamulizumab before allo-hematopoietic stem cell transplantation (HSCT) strongly indicated a high incidence of severe acute graft-versus-host-disease... | research_paper |
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTFiber-Optic Chemical Sensors and BiosensorsOtto S. WolfbeisView Author Information Institute of Analytical Chemistry, University of Regensburg, D-93040 Regensburg, Germany Cite this: Anal. Chem. 2006, 78, 12, 3859–3874Publication Date (Web):April 15, 2006Publication History Pu... | literature_review |
Interferon (IFN-alpha) increased estrogen receptor (ER) activity in human breast cancer tissue, human uterus (endometrium), and rabbit uterus. The optimum response was obtained with three different doses of IFN-alpha 10, 100, and 1000 U per ml. Escalation of the dose up to 5000 U per ml did not increase further ER acti... | research_paper |
The authors assessed the association of smoking with dementia and cognitive decline in a meta-analysis of 19 prospective studies with at least 12 months of follow-up. Studies included a total of 26,374 participants followed for dementia for 2-30 years and 17,023 participants followed up for 2-7 years to assess cognitiv... | literature_review |
Photocatalysis has been widely applied in various areas, such as solar cells, water splitting, and pollutant degradation. Therefore, the photochemical mechanisms and basic principles of photocatalysis, especially TiO<sub>2</sub> photocatalysis, have been extensively investigated by various surface science methods in th... | literature_review |
Abstract Using a mouse model of neonatal respiratory distress syndrome (RDS), we demonstrate a central role for macrophage migration inhibitory factor (MIF) in lung maturation at the developmental stage when human neonates are most susceptible to RDS. We prematurely delivered mouse pups at embryonic day 18, during the ... | research_paper |
Drug-metabolizing enzymes, drug transporters and drug targets play significant roles as determinants of drug efficacy and toxicity. Their genetic polymorphisms often affect the expression and function of their products and are expected to become surrogate markers to predict the response to drugs in individual patients.... | research_paper |
OBJECTIVE: In this paper, we review the mechanisms thought to be involved in the activation of osteoclasts in periodontitis. SUMMARY Osteoclasts are regulated by both microbial and host factors. Some factors act directly on cells of the osteoclast lineage, whereas others act indirectly through other cell types in the b... | research_paper |
<b>Aim:</b> To assess the diagnostic value of selected miRNAs from various material collected from hepatocellular carcinoma (HCC) patients. <b>Patients & methods:</b> Tissue, serum, urine and fecal samples from HCC patients and healthy individuals were screened for associated miRNAs using microarray analysis; the selec... | research_paper |
Existing fair ranking systems, especially those designed to be demographically fair, assume that accurate demographic information about individuals is available to the ranking algorithm. In practice, however, this assumption may not hold -- in real-world contexts like ranking job applicants or credit seekers, social an... | research_paper |
Control of a flexible launcher during the atmospheric flight phase is a highly challenging control problem involving multiple and concurrent design requirements: stability (stabilization of unstable rigid dynamics, sloshing modes and flexible structural modes), performance (guidance tracking, structural load minimizati... | research_paper |
Studies supporting the notion that physical activity and exercise can help alleviate the negative impact of age on the body and the mind abound. This literature review provides an overview of important findings in this fast growing research domain. Results from cross-sectional, longitudinal, and intervention studies wi... | literature_review |
INTRODUCTION: Reticular erythematous mucinosis (REM) is a rare chronic dermatosis, predominantly affecting middle age women, characterized by net-like macules and patches on the chest and back. The etiology of REM is uncertain, though associations with environmental, hormonal, and autoimmune factors have been suggested... | literature_review |
D2C7-immunotoxin (IT), a dual-specific IT targeting wild-type epidermal growth factor receptor (EGFR) and mutant EGFR variant III (EGFRvIII) proteins, demonstrates encouraging survival outcomes in a subset of patients with glioblastoma. We hypothesized that immunosuppression in glioblastoma limits D2C7-IT efficacy. To ... | research_paper |
Insulin has been used for diabetes therapy and has achieved significant therapeutic effect. In recent years, the use of purified and recombinant human insulin preparations has markedly reduced, but not completely suppressed, the incidence of insulin antibodies (IAs). IAs induced by exogenous insulin in diabetic patient... | research_paper |
Adjacent cells share ions, second messengers and small metabolites through intercellular channels which are present in gap junctions. This type of intercellular communication permits coordinated cellular activity, a critical feature for organ homeostasis during development and adult life of multicellular organisms. Int... | literature_review |
Forty patients with active hemorrhoidal disease were entered into this double-blind trial, 20 of whom were randomized to treatment with 5-aminosalicylic acid (5-ASA) (500 mg) suppositories. Clinical and sigmoidoscopic assessment was carried out before the start of the trial and after two weeks of treatment. At the end ... | research_paper |
Survival after pediatric lung transplantation is primarily limited by the development of chronic lung allograft dysfunction (CLAD). Currently, no standardized guidelines exist, and data on the prevention, diagnosis, treatment, and management of CLAD in pediatric patients are limited. This scoping review will map and su... | literature_review |
Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It is possible to insert foreign peptides or proteins at its ten-amino acid termini. These chimeras elicit systemic and oral immunity without adjuvants, which are commonly needed in the formulation of subunit-based vaccines. Here, we ... | research_paper |
Gallbladder cancer, though generally considered rare, is the most common malignancy of the biliary tract, accounting for 80%-95% of biliary tract cancers. An early diagnosis is essential as this malignancy progresses silently with a late diagnosis, often proving fatal. Its carcinogenesis follows a progression through a... | literature_review |
This study evaluated the validity of monitoring for Escherichia coli in lieu of Cryptosporidium to assess the vulnerability of source waters to the presence of Cryptosporidium oocysts. Over a period of seven years, four large water systems in Utah collected Cryptosporidium, E. coli, and turbidity data from seven water ... | research_paper |
Immune-checkpoint inhibitors (ICIs) play a key role in the treatment of advanced stage colorectal cancer (CRC) patients featuring a deficient DNA mismatch repair (dMMR) system or a high microsatellite instability (MSI-H) profile. However, beyond the established role in CRC patients, ICIs have highly proven efficacy in ... | research_paper |
Tumor necrosis factor alpha (TNF-alpha) is an immunoregulatory cytokine with many biological activities including the mediation of inflammation. We examined sera and synovial fluids from patients seropositive for infection with Borrelia burgdorferi using a radioimmunoassay specific for TNF-alpha. Significant elevation ... | research_paper |
Distribution services are an important driver of growth in East Africa. With contributions to gross domestic product (GDP) ranging from about 11 percent in Kenya, Rwanda, and Tanzania to more than 14 percent in Uganda in 2008/09 distribution services are a significant part of all East African economies. The sector also... | research_paper |
Abstract Injection of antigen into the anterior chamber (AC) of the eye, animmunologically privileged site, is associated with the inductionof immune deviation, as evidenced by T helper cell (Th) 1 to Th2 cellpolarization. We recently demonstrated that AC-associated immunedeviation (ACAID) is a thymus-dependent phenome... | research_paper |
This is the first review to synthesize virtual global health education activities for graduate medical trainees. Our review identified important drivers and challenges to these activities, the need for future study on activity preferences, and considerations for learners and educators in low- to middle-income countries... | literature_review |
The synthesis of caprine arthritis-encephalitis virus structural proteins was analysed in infected cells labelled with [35S]methionine and [3H]glucosamine and by translation of virion RNA in vitro. Viral polypeptides were isolated from infected cell lysates or from in vitro translation products by immunoprecipitation w... | research_paper |
Summary: Basal, activation, and arrest signaling in T cells determines survival, coordinates responses to pathogens, and, when dysregulated, leads to loss of self‐tolerance and autoimmunity. At the T‐cell surface, transmembrane glycoproteins interact with galectins via their N ‐glycans, forming a molecular lattice that... | research_paper |
We present a TSC multivalued I2L comparator which uses multivalued current inputs and two binary voltage outputs. This circuit is self-testing and fault-secure for single faults (either "stuck-at" or "skew" faults). It is the basic circuit to realize TSC checkers for nonseparable or separable codes. The schemes are sim... | research_paper |
In conclusion, we have successfully demonstrated a 10-Gbit/s four channel WDM transmission over a 2400-km dispersion shifted fibre (DSF) using the optical DPSK-DD direct detection system. This distance is long enough for terrestrial networks. High Q-factors were achieved in 1600-km and 2400-km DSP transmissions as comp... | research_paper |
In a pooled analysis of data from 5 statin trials, intensive-dose statin therapy was associated with an increased risk of new-onset diabetes compared with moderate-dose statin therapy. | literature_review |
New architecture for a DLL based frequency multiplier for wireless transceivers presents in this paper. This architecture has the advantages of occupying low area, low power, low voltage and low phase noise. Also good stability can be obtained in this design. This structure also can be used for generating big multiples... | research_paper |
Aims To describe the details of dyadic interventions and summarize the current evidence on supporting dyadic interventions for psycho-social outcomes of stroke patients and their caregivers. Design A systematic review and meta-analysis based on PRISMA guidelines. Data sources Five English databases (PubMed, Web of Scie... | literature_review |
The oral cavity is a very rare site for metastases, it was described in a number of cancers e.g.lung, breast, colon and prostate cancers.Prostate cancer with oral metastasis is uncommon and accounts for less than 2% of oral malignancies.We report a case of buccal mucosa metastases from ca prostate primary, confirmed by... | literature_review |
ABSTRACT Lacticin 3147 is a two-peptide (LtnA1 and LtnA2) lantibiotic produced by Lactococcus lactis subsp. lactis DPC3147 and has inhibitory activity against all gram-positive microorganisms tested. In this study the specific activities of the component peptides (alone or in combination) were determined by using L. la... | research_paper |
The G protein-coupled metabotropic glutamate (mGlu) receptors are differentially localized at various synapses throughout the brain. Depending on the receptor subtype, they appear to be localized at presynaptic and/or postsynaptic sites, including glial as well as neuronal elements. The heterogeneous distribution of th... | literature_review |
The goal of making silage is to produce a stable feed with a high recovery of dry matter, energy, and highly digestible nutrients compared with the fresh crop. Microbial fermentation in the silo produces an array of end products and can change many nutritive aspects of a forage. High-quality silage should be void of un... | literature_review |
Abstract Glioblastoma multiforme is the most common primary malignant brain tumor and despite treatment with surgery, radiation, and chemotherapy, the median survival of patients with glioblastoma multiforme is ∼1 year. Glioblastoma multiforme explants and cell lines have been reported to overexpress the interleukin-13... | research_paper |
We have undertaken a systematic review and meta-analysis to investigate the association between maternal exposure to air pollutants and outcomes of in vitro fertilization (IVF). Studies were identified through a comprehensive online search. After standardizing all air pollution concentrations to 10 μg/m<sup>3</sup>, we... | literature_review |
This paper reviews ultrasound segmentation paper methods, in a broad sense, focusing on techniques developed for medical B-mode ultrasound images. First, we present a review of articles by clinical application to highlight the approaches that have been investigated and degree of validation that has been done in differe... | literature_review |
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