id
stringlengths
36
36
input
stringlengths
26
1.82k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
int64
0
3
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
output
stringlengths
4
290
options
stringlengths
19
1.16k
letter
stringclasses
56 values
incorrect_letters
listlengths
3
3
incorrect_answers
listlengths
3
3
single_incorrect_answer
stringlengths
4
289
system_prompt
stringclasses
1 value
messages
listlengths
2
2
983f65c2-e0ac-4b6c-be94-51f4d0afd0b7
Organism that does NOT need vector for transmission: a. Coxiella burnetii b. Rickettsia rickettsii c. Borrelia recurrentis d. Rickettsia prowazekii
Rickettsia prowazekii
Rickettsia rickettsii
Coxiella burnetii
Borrelia recurrentis
2
single
Coxiella burnetii causes Q fever. Q fever transmission differs from other rickettsial infection in that there is no ahropod involved in its transmission to man. Transmission results from inhalation, ingestion, abrasion or directly in conjunctiva. Ref: Park 21st edition, page 276.
Social & Preventive Medicine
null
a. Coxiella burnetii
a. Coxiella burnetii b. Rickettsia rickettsii c. Borrelia recurrentis d. Rickettsia prowazekii
a.
[ "b.", "c.", "d." ]
[ "b. Rickettsia rickettsii", "c. Borrelia recurrentis", "d. Rickettsia prowazekii" ]
b. Rickettsia rickettsii
Choose the correct answer from the options below.
[ { "content": "Organism that does NOT need vector for transmission:\n\na. Coxiella burnetii\nb. Rickettsia rickettsii\nc. Borrelia recurrentis\nd. Rickettsia prowazekii", "role": "user" }, { "content": "a. Coxiella burnetii", "role": "assistant" } ]
7ca2027e-160f-4c6b-b62d-49f0402f4115
Immune reconstitution inflammatory syndrome typically occurs following anti retroviral therapy after a duration of: I. 6-12 months II. 2-6 weeks III. 1-2 weeks IV. 1-2 years
1-2 weeks
2-6 weeks
6-12 months
1-2 years
1
multi
Typically immune reconstitution inflammatory syndrome occurs within 2-12weeksof initiation of A, though it may present later between 6 weeks to 6 months. Ref:
Social & Preventive Medicine
null
II. 2-6 weeks
I. 6-12 months II. 2-6 weeks III. 1-2 weeks IV. 1-2 years
II.
[ "I.", "III.", "IV." ]
[ "I. 6-12 months", "III. 1-2 weeks", "IV. 1-2 years" ]
I. 6-12 months
Choose the correct answer from the options below.
[ { "content": "Immune reconstitution inflammatory syndrome typically occurs following anti retroviral therapy after a duration of:\n\nI. 6-12 months\nII. 2-6 weeks\nIII. 1-2 weeks\nIV. 1-2 years", "role": "user" }, { "content": "II. 2-6 weeks", "role": "assistant" } ]
f7a51603-5d03-4538-a682-d1a9992ea83f
. Gall stones - I. Are usually more than 50 mm in diameter II. About 80-90% of gall stones are radio-opaque III. There is an increased incidence of stones in diabetics IV. Are about twice as common in men as in women
Are about twice as common in men as in women
There is an increased incidence of stones in diabetics
About 80-90% of gall stones are radio-opaque
Are usually more than 50 mm in diameter
1
multi
null
Surgery
null
III. There is an increased incidence of stones in diabetics
I. Are usually more than 50 mm in diameter II. About 80-90% of gall stones are radio-opaque III. There is an increased incidence of stones in diabetics IV. Are about twice as common in men as in women
III.
[ "I.", "II.", "IV." ]
[ "I. Are usually more than 50 mm in diameter", "II. About 80-90% of gall stones are radio-opaque", "IV. Are about twice as common in men as in women" ]
II. About 80-90% of gall stones are radio-opaque
Choose the correct answer from the options below.
[ { "content": ". Gall stones -\n\nI. Are usually more than 50 mm in diameter\nII. About 80-90% of gall stones are radio-opaque\nIII. There is an increased incidence of stones in diabetics\nIV. Are about twice as common in men as in women", "role": "user" }, { "content": "III. There is an increased incidence of stones in diabetics", "role": "assistant" } ]
bf442290-30a0-4fc2-be12-4fdaf82c1052
Maximum infection of CMV is seen after what duration post transplantation ? A. 1-4 months B. Immediate C. < 1 month D. > 6 months
Immediate
< 1 month
1-4 months
> 6 months
2
single
.Therapeutic invasive procedures may be in the form of IV cannula, bladder catheter, tracheostomy and other minor surgical procedures which permit the skin organisms like staphylococcus epidermidis to penetrate the skin and invade the deeper tissues. Organisms Bacteria: Gram-negative: E. coli, Pseudomonas, Klebsiella, Proteus, Serratia. Gram-positive: Staphylococcus epidermidis, Streptococcus pneumoniae. Viruses: Herpes, CMV, Varicella zoster, may cause fatal pneumonia. ref:SRB&;s manual of surgery,ed 3,pg no 59
Surgery
Urology
A. 1-4 months
A. 1-4 months B. Immediate C. < 1 month D. > 6 months
A.
[ "B.", "C.", "D." ]
[ "B. Immediate", "C. < 1 month", "D. > 6 months" ]
D. > 6 months
Choose the correct answer from the options below.
[ { "content": "Maximum infection of CMV is seen after what duration post transplantation ?\n\nA. 1-4 months\nB. Immediate\nC. < 1 month\nD. > 6 months", "role": "user" }, { "content": "A. 1-4 months", "role": "assistant" } ]
05e0ae28-e7f8-45c9-90be-31dfd6565fb9
All are typical electron microscopic features of Alpo syndrome, EXCEPT: a. Multi Lamellation of the lamina densa b. Irregular thickening of GBM c. Basket weave pattern of lamina densa d. Thickening of the renal tubules
Irregular thickening of GBM
Multi Lamellation of the lamina densa
Basket weave pattern of lamina densa
Thickening of the renal tubules
3
multi
Typical electron microscopic changes in Alpo syndrome: 1. Irregular thickening of the GBM of up to 4 or 5 times the normal thickness, 2. Multi Lamellation of the lamina densa forming a "basket weave" pattern by inclusion of electron lucent areas, often containing round, dense granules, measuring 20-60 nm in diameter. The earliest manifestation of the GBM is irregular thinning, and the extent and severity of thickening and multi lamellation increases with age. These changes are often widespread especially in adults. Ref: Dan Med Bull 2009; 56:105-52.
Medicine
null
d. Thickening of the renal tubules
a. Multi Lamellation of the lamina densa b. Irregular thickening of GBM c. Basket weave pattern of lamina densa d. Thickening of the renal tubules
d.
[ "a.", "b.", "c." ]
[ "a. Multi Lamellation of the lamina densa", "b. Irregular thickening of GBM", "c. Basket weave pattern of lamina densa" ]
b. Irregular thickening of GBM
Choose the correct answer from the options below.
[ { "content": "All are typical electron microscopic features of Alpo syndrome, EXCEPT:\n\na. Multi Lamellation of the lamina densa\nb. Irregular thickening of GBM\nc. Basket weave pattern of lamina densa\nd. Thickening of the renal tubules", "role": "user" }, { "content": "d. Thickening of the renal tubules", "role": "assistant" } ]
cf0feb9a-978f-4872-bd72-0aba80d97e8f
An asymptomatic 3-yrs-old is brought to you because of right cheek swelling. The mother states that the patient had been in his normal state of health until 1 hour ago, when he developed right cheek swelling. The patient is afebrile. Examination is unremarkable except for the right cheek, which is erythematous but not warm to touch. On palpation of the right cheek, mildly tender, discrete, indurated masses are appreciated. Which is the most likely cause? (1) Panniculitis (2) Trauma (3) Cellulitis (4) Erysipelas
Erysipelas
Cellulitis
Trauma
Panniculitis
3
multi
Panniculitis is secondary to cold injury to fat and is characterized by the development of indurated lesions that resemble buccal cellutitis. Young children who hold popsicles in their mouths may be prone to panniculitis. Erysipelas is an acute, well-demarcated infection of the skin with lymphangitis. The patient with erysipelas usually appears ill with fever, vomiting, and irritability. Cellulitis usually has distinct margins and is tender, indurated, and warm to touch. There is no history of trauma, nor is there any evidence of bruising or abrasions. Contact dermatitis has an erythematous or papulovesicular rash in area that was exposed to contactant
Surgery
null
(1) Panniculitis
(1) Panniculitis (2) Trauma (3) Cellulitis (4) Erysipelas
(1)
[ "(2)", "(3)", "(4)" ]
[ "(2) Trauma", "(3) Cellulitis", "(4) Erysipelas" ]
(4) Erysipelas
Choose the correct answer from the options below.
[ { "content": "An asymptomatic 3-yrs-old is brought to you because of right cheek swelling. The mother states that the patient had been in his normal state of health until 1 hour ago, when he developed right cheek swelling. The patient is afebrile. Examination is unremarkable except for the right cheek, which is erythematous but not warm to touch. On palpation of the right cheek, mildly tender, discrete, indurated masses are appreciated. Which is the most likely cause?\n\n(1) Panniculitis\n(2) Trauma\n(3) Cellulitis\n(4) Erysipelas", "role": "user" }, { "content": "(1) Panniculitis", "role": "assistant" } ]
05ab1d47-abcd-4ede-a157-5c0f0535a112
Prevalence of all clinical cases of polio can be estimated by multiplying the no. of residual paralytic cases by - 1) 3 2) 1.33 3) 1.25 4) 1.99
1.33
1.25
3
1.99
0
multi
Ans. is 'a' i.e., 1.33 o The most accurate technique to measure the prevalence of polio in a community is a 'house to house' survey of 'lameness and muscle wasting' due to polio (in children between 5-10 years). The total prevalence of residual paralysis due to poliomyelitis could then be estimated by multiplying prevalence of lameness by a factor of 1.25 and repoing it as cases per 1000. However, all clinical cases of polio do not result in residual paralysis. About one fouh of the clinical cases, result in deaths or complete recovery, etc. and therefore are missed in a survey for residual paralysis. This indicates that the actual prevalence of all clinical cases will be more than that of residual paralysis. The total prevalence of all clinical cases could be made by multiplying the prevalence rate of residual paralysis by a factor of 1.33.
Social & Preventive Medicine
null
2) 1.33
1) 3 2) 1.33 3) 1.25 4) 1.99
2)
[ "1)", "3)", "4)" ]
[ "1) 3", "3) 1.25", "4) 1.99" ]
3) 1.25
Choose the correct answer from the options below.
[ { "content": "Prevalence of all clinical cases of polio can be estimated by multiplying the no. of residual paralytic cases by -\n\n1) 3\n2) 1.33\n3) 1.25\n4) 1.99", "role": "user" }, { "content": "2) 1.33", "role": "assistant" } ]
29a8fcef-cac1-4c7a-82e0-9dcdc89c64cd
Alpha 1 antitrypsin deficiency is associated with- [A] Irregular-emphysema [B] Paraseptal-emphysema [C] Panacinar-emphysema [D] Centriacinar-emphysema
Panacinar-emphysema
Centriacinar-emphysema
Paraseptal-emphysema
Irregular-emphysema
0
single
Ans. is 'a' i.e., Panacinar-emphysema Pathogenesis of Emphysemao The most accepted theory in the pathogenesis of emphysema is protease - antiprotease mechanism which is responsible in the pathogenesis of two common forms of emphysema, i.e. centriacinar and panacinar.o The alveolar wall destruction results from an imbalance between proteases (mainly elastase) and antiproteases in the lung.o Proteases (elastase) cause destruction of alveolar wall, while antiproteases prevent this damage,o a1 antitrypsin is the major antiprotease (antieiastase) secreted by neutrophils during inflammation.A. Pathogenesis of panacinar emphysemao Panacinar emphysema is associated with congenital deficiency of a1.-antitrypsin.o This results in unchecked overactivity of neutrophil elastase that causes destruction of alveolar wall,o As a,-antitrypsin is deficient throughout the acinus, the acini are uniformly involved from the respiratoiy bronchiole to the terminal blind alveoli.o Neutrophils are the major cells in the pathogenesis of panacinar emphysemaB. Pathogenesis of centriacinar emphysemao Centriacinar emphysema is associated with smoking.o Nicotine acts as a direct chemoattractant for neutrophils and macrophages,o So, in centriacinar emphysema, both neutrophils and macrophages play central role,o Smoking enhances activity of neutrophil and macrophage elastase.o Macrophage elastase is not inhibited by a1-antitrypsin and indeed can proteolvticallv digest this antiprotease,o Beside protease - antiprotease mechanism, oxidant - antioxidant imbalance also plays an important role in the pathogenesis of smoking related emphysema.o Normally, the lung contains a healthy complement of antioxidants (superoxide dismutase, glutathione),o Tobacco smoke contains abundant reactive oxygen species (free radicals) which deplete these antioxidant mechanisms.o Free radicals cause tissue damage as well as they inactivate a(-antitrypsin, resulting in functional a,- antitrypsin deficiency even in patients without enzyme deficiency.
Pathology
Obstructive Lung Diseases
[C] Panacinar-emphysema
[A] Irregular-emphysema [B] Paraseptal-emphysema [C] Panacinar-emphysema [D] Centriacinar-emphysema
[C]
[ "[A]", "[B]", "[D]" ]
[ "[A] Irregular-emphysema", "[B] Paraseptal-emphysema", "[D] Centriacinar-emphysema" ]
[B] Paraseptal-emphysema
Choose the correct answer from the options below.
[ { "content": "Alpha 1 antitrypsin deficiency is associated with-\n\n[A] Irregular-emphysema\n[B] Paraseptal-emphysema\n[C] Panacinar-emphysema\n[D] Centriacinar-emphysema", "role": "user" }, { "content": "[C] Panacinar-emphysema", "role": "assistant" } ]
403778ba-ada7-4e4e-bab9-eccb4d0357ad
Uric acid is formed by A) Catabolism of pyrimidines B) Catabolism of ketones C) Catabolism of proteins D) Catabolism of purines
Catabolism of proteins
Catabolism of ketones
Catabolism of purines
Catabolism of pyrimidines
2
single
Uric acid the end product of purine catabolismis a strong reducing agent. Its role as an antioxidant is paicularly significant in the upper respiratory tract REF : DM VASUDEVAN TEXTBOOK ;8th EDITION ;Page no:547 and 548
Biochemistry
Metabolism of nucleic acids
D) Catabolism of purines
A) Catabolism of pyrimidines B) Catabolism of ketones C) Catabolism of proteins D) Catabolism of purines
D)
[ "A)", "B)", "C)" ]
[ "A) Catabolism of pyrimidines", "B) Catabolism of ketones", "C) Catabolism of proteins" ]
C) Catabolism of proteins
Choose the correct answer from the options below.
[ { "content": "Uric acid is formed by\n\nA) Catabolism of pyrimidines\nB) Catabolism of ketones\nC) Catabolism of proteins\nD) Catabolism of purines", "role": "user" }, { "content": "D) Catabolism of purines", "role": "assistant" } ]
251ddabd-685a-4090-a471-4977be2c25c1
Which of the following is positive in Follicular lymphoma (1) None of the above (2) Bcl 2 (3) Bcl 1 (4) Bcl 6
Bcl 2
Bcl 6
Bcl 1
None of the above
0
multi
* Burkitt lymphoma and Follicular lymphoma arises from Germinal center B cell * Mantle cell lymphoma arises from Naive B cell * Hairy cell leukemia and extranodal marginal zone lymphoma arises from Memory B cell Translocation In :- * Burkitt lymphoma t (8:14) * Follicular lymphoma t (14:18) * Mantle zone lymphoma t(11:14) * Marginal Zone lymphoma t(11:18) CD23 is negative in Mantle cell lymphoma Ref:- Robbins Basic Pathology 9th Edition; Pg num:- 468,469
Pathology
Haematology
(2) Bcl 2
(1) None of the above (2) Bcl 2 (3) Bcl 1 (4) Bcl 6
(2)
[ "(1)", "(3)", "(4)" ]
[ "(1) None of the above", "(3) Bcl 1", "(4) Bcl 6" ]
(1) None of the above
Choose the correct answer from the options below.
[ { "content": "Which of the following is positive in Follicular lymphoma\n\n(1) None of the above\n(2) Bcl 2\n(3) Bcl 1\n(4) Bcl 6", "role": "user" }, { "content": "(2) Bcl 2", "role": "assistant" } ]
2a4e24cc-65cb-407e-9006-15f0d7ada202
According to Pikham pediatric Dentistry what is the treatment in a child having laterally luxated teeth which are not in occlusion: A) Grind the opposite teeth. B) Wait and watch. C) Immediate repositioning of the teeth. D) Extraction.
Wait and watch.
Grind the opposite teeth.
Extraction.
Immediate repositioning of the teeth.
2
multi
Immediate treatment in a laterally luxated tooth is immediate repositioning and stabilization. But according to Pikham Pediatric Dentistry, he recommends extraction of Laterally luxated teeth because of the fear of aspiration.
Dental
null
D) Extraction.
A) Grind the opposite teeth. B) Wait and watch. C) Immediate repositioning of the teeth. D) Extraction.
D)
[ "A)", "B)", "C)" ]
[ "A) Grind the opposite teeth.", "B) Wait and watch.", "C) Immediate repositioning of the teeth." ]
A) Grind the opposite teeth.
Choose the correct answer from the options below.
[ { "content": "According to Pikham pediatric Dentistry what is the treatment in a child having laterally luxated teeth which are not in occlusion:\n\nA) Grind the opposite teeth.\nB) Wait and watch.\nC) Immediate repositioning of the teeth.\nD) Extraction.", "role": "user" }, { "content": "D) Extraction.", "role": "assistant" } ]
c1d927bd-14f6-4d48-8420-54ead23e6bcf
An asymptomatic male came for USG abdomen for medical fitness. A focal lesion was found in his liver on ultrasound as shown here. The patient was told that this is the most common benign hepatic tumor. Which of the following is a false statement about this lesion? A. Characteristic Centripetal fill-in appearance is seen on postcontrast study. B. Angiography shows characteristic "cotton-wool" appearance. C. Most of these lesions are asymptomatic D. The most sensitive and specific investigation CT Triphasic Contrast
The most sensitive and specific investigation CT Triphasic Contrast
Most of these lesions are asymptomatic
Characteristic Centripetal fill-in appearance is seen on postcontrast study.
Angiography shows characteristic "cotton-wool" appearance.
0
multi
Ans. A. The most sensitive and specific investigation CT Triphasic ContrastHemangiomas are the commonest benign hepatic tumors with a prevalence at postmortem of between 4 per cent and 20 per cent. Multiple hemangiomas occur in up to 10 per cent of cases. They are composed of vascular channels of varying size (cavernous to capillary), lined with endothelium, often with intervening fibrous tissue of varying amounts. Most hemangiomas are asymptomatic, incidental findings on imaging. Those between approximately 2 and 4 cm in diameter are most likely to possess characteristic features allowing a confident diagnosis by imaging alone.
Radiology
G.I.T.
D. The most sensitive and specific investigation CT Triphasic Contrast
A. Characteristic Centripetal fill-in appearance is seen on postcontrast study. B. Angiography shows characteristic "cotton-wool" appearance. C. Most of these lesions are asymptomatic D. The most sensitive and specific investigation CT Triphasic Contrast
D.
[ "A.", "B.", "C." ]
[ "A. Characteristic Centripetal fill-in appearance is seen on postcontrast study.", "B. Angiography shows characteristic \"cotton-wool\" appearance.", "C. Most of these lesions are asymptomatic" ]
C. Most of these lesions are asymptomatic
Choose the correct answer from the options below.
[ { "content": "An asymptomatic male came for USG abdomen for medical fitness. A focal lesion was found in his liver on ultrasound as shown here. The patient was told that this is the most common benign hepatic tumor. Which of the following is a false statement about this lesion?\n\nA. Characteristic Centripetal fill-in appearance is seen on postcontrast study.\nB. Angiography shows characteristic \"cotton-wool\" appearance.\nC. Most of these lesions are asymptomatic\nD. The most sensitive and specific investigation CT Triphasic Contrast", "role": "user" }, { "content": "D. The most sensitive and specific investigation CT Triphasic Contrast", "role": "assistant" } ]
b92bcb87-dc43-4755-a662-1c3a2fc698f8
Commonest site for carcinoma of the breast- [1] Nipple [2] Upper outer quadrant [3] Lower inner quadrant [4] Upper inner quadrant
Lower inner quadrant
Nipple
Upper inner quadrant
Upper outer quadrant
3
single
null
Surgery
null
[2] Upper outer quadrant
[1] Nipple [2] Upper outer quadrant [3] Lower inner quadrant [4] Upper inner quadrant
[2]
[ "[1]", "[3]", "[4]" ]
[ "[1] Nipple", "[3] Lower inner quadrant", "[4] Upper inner quadrant" ]
[3] Lower inner quadrant
Choose the correct answer from the options below.
[ { "content": "Commonest site for carcinoma of the breast-\n\n[1] Nipple\n[2] Upper outer quadrant\n[3] Lower inner quadrant\n[4] Upper inner quadrant", "role": "user" }, { "content": "[2] Upper outer quadrant", "role": "assistant" } ]
b2173dce-e6ef-48aa-bc40-a18f86b4f016
Paltauf's hemorrhage may be seen in: (a) Snake bite (b) Rape (c) Drowning. (d) Hanging
Drowning.
Hanging
Snake bite
Rape
0
single
Ans. a (Drowning)In drowning, fluid actually penetrates alveolar wall to enter tissues & the blood vessels.The alveolar wall may rupture due to increased pressure during the forced expiration & produce hemorrhage which when presents subpleurally is called Paltauf 's haemorrhage.Paltauf's haemorrhages are shining, pale bluish red, & may be minute or 3 to 5 cm in diameter.
Forensic Medicine
Asphyxial Deaths
(c) Drowning.
(a) Snake bite (b) Rape (c) Drowning. (d) Hanging
(c)
[ "(a)", "(b)", "(d)" ]
[ "(a) Snake bite", "(b) Rape", "(d) Hanging" ]
(a) Snake bite
Choose the correct answer from the options below.
[ { "content": "Paltauf's hemorrhage may be seen in:\n\n(a) Snake bite\n(b) Rape\n(c) Drowning.\n(d) Hanging", "role": "user" }, { "content": "(c) Drowning.", "role": "assistant" } ]
83cdea73-2ee5-472f-b7c6-600cb98167b4
Following total thyroidectomy the patient develops respiratory stridor. The cause is: a) B/L complete paralysis b) B/L recurrent laryngeal nerve paralysis c) U/L complete paralysis d) U/L recurrent laryngeal nerve paralysis
B/L recurrent laryngeal nerve paralysis
B/L complete paralysis
U/L recurrent laryngeal nerve paralysis
U/L complete paralysis
0
single
(a) B/L recurrent laryngeal nerve paralysis(Ref. Current Diagnosis & Treatment Otolaryngology, Lalwani, 3rd ed., 478)In B/L recurrent laryngeal nerve paralysis the vocal cords will be in median position, leading to stridor.Note: This is the only vocal cord palsy with stridor, breathing is normal in the remaining palsies.
ENT
Larynx
b) B/L recurrent laryngeal nerve paralysis
a) B/L complete paralysis b) B/L recurrent laryngeal nerve paralysis c) U/L complete paralysis d) U/L recurrent laryngeal nerve paralysis
b)
[ "a)", "c)", "d)" ]
[ "a) B/L complete paralysis", "c) U/L complete paralysis", "d) U/L recurrent laryngeal nerve paralysis" ]
d) U/L recurrent laryngeal nerve paralysis
Choose the correct answer from the options below.
[ { "content": "Following total thyroidectomy the patient develops respiratory stridor. The cause is:\n\na) B/L complete paralysis\nb) B/L recurrent laryngeal nerve paralysis\nc) U/L complete paralysis\nd) U/L recurrent laryngeal nerve paralysis", "role": "user" }, { "content": "b) B/L recurrent laryngeal nerve paralysis", "role": "assistant" } ]
613e5863-58f1-48e5-8b9f-a3b68c35f0b0
Movement of denture base was the least in patient with poor ridges, when [1] 20 degree teeth were used [2] Inverted cusp teeth were used [3] 33 degree teeth were used [4] 0 degree teeth were used
20 degree teeth were used
33 degree teeth were used
0 degree teeth were used
Inverted cusp teeth were used
2
single
null
Dental
null
[4] 0 degree teeth were used
[1] 20 degree teeth were used [2] Inverted cusp teeth were used [3] 33 degree teeth were used [4] 0 degree teeth were used
[4]
[ "[1]", "[2]", "[3]" ]
[ "[1] 20 degree teeth were used", "[2] Inverted cusp teeth were used", "[3] 33 degree teeth were used" ]
[2] Inverted cusp teeth were used
Choose the correct answer from the options below.
[ { "content": "Movement of denture base was the least in patient with poor ridges, when\n\n[1] 20 degree teeth were used\n[2] Inverted cusp teeth were used\n[3] 33 degree teeth were used\n[4] 0 degree teeth were used", "role": "user" }, { "content": "[4] 0 degree teeth were used", "role": "assistant" } ]
8d5efc6b-fed6-45b9-996b-e0b80ae98abf
Lowe's syndrome is characterised by the following except- i. Aminoaciduria ii. Undescended testes iii. Hypophosphatamic rickets iv. Defect in the CNS and eyes
Hypophosphatamic rickets
Undescended testes
Defect in the CNS and eyes
Aminoaciduria
1
multi
Ans. is 'b' i.e., Undescendended testes Lowe's syndrome It is also known as oculocerebrorenal syndrome of Lowe. o It is X-linked disorder. It is characterized by : i) Congenital cataract ii) Mental retardation iii) Fanconi syndrome --> Aminoacidurina o The disease is caused by mutation in the OCRL1 gene, which encodes the phosphatidylinosital polyphosphate 5-phasphatase. Clinical features Progressive growth failure Hypotonia Fanconi syndrome Significant proteinuria Blindness Renal infufficiency Behavioural problems
Pediatrics
null
ii. Undescended testes
i. Aminoaciduria ii. Undescended testes iii. Hypophosphatamic rickets iv. Defect in the CNS and eyes
ii.
[ "i.", "iii.", "iv." ]
[ "i. Aminoaciduria", "iii. Hypophosphatamic rickets", "iv. Defect in the CNS and eyes" ]
i. Aminoaciduria
Choose the correct answer from the options below.
[ { "content": "Lowe's syndrome is characterised by the following except-\n\ni. Aminoaciduria\nii. Undescended testes\niii. Hypophosphatamic rickets\niv. Defect in the CNS and eyes", "role": "user" }, { "content": "ii. Undescended testes", "role": "assistant" } ]
ed8d4a38-0474-44cd-8fb1-06c10714f07f
Which amino acid plays a vital role in Neutrophil extracellular traps? A. Arginine B. Valine C. Aspartic acid D. Isoleucine
Arginine
Valine
Isoleucine
Aspartic acid
0
single
Arginine amino acid is required for breakdown of histone polynucleotidyl complexes necessary for neutrophilic extra cellular trap.
Pathology
null
A. Arginine
A. Arginine B. Valine C. Aspartic acid D. Isoleucine
A.
[ "B.", "C.", "D." ]
[ "B. Valine", "C. Aspartic acid", "D. Isoleucine" ]
C. Aspartic acid
Choose the correct answer from the options below.
[ { "content": "Which amino acid plays a vital role in Neutrophil extracellular traps?\n\nA. Arginine\nB. Valine\nC. Aspartic acid\nD. Isoleucine", "role": "user" }, { "content": "A. Arginine", "role": "assistant" } ]
b6ecd5e4-8fea-40e6-89db-012d5f42dd83
Hydrolysis of which of the following yields 10.5 Kcal energy? i. UTP ii. GTP iii. ATP iv. Creatine phosphate
ATP
GTP
UTP
Creatine phosphate
3
single
ANSWER: (D) Creatine phosphateREF: Harper 28th ed Table 11-1Free Energy of Hydrolysis of Some Organophosphates of Biochemical Importance DGdegCompoundkJ/molkcal/molPhosphoenolpyruvate-61.9-14.8Carbamoyl phosphate-51.4-12.31,3-Bispbosphoglycerate (to 3-phosphogiycerate)-49.3-11.8Creatine phosphate-43.1-10.3ATP - AMP + PPi-32.2-7.7ATP - ADP + Pi-30.5-7.3Glucose 1-phosphate-20.9-5.0PPi-19.2-4.6Fructose 6-phosphate-15.9-3.8Glucose 6-phosphate-13.8-3.3Glycerol 3-phosphate-9.2-2.2
Biochemistry
Respiratory Chain
iv. Creatine phosphate
i. UTP ii. GTP iii. ATP iv. Creatine phosphate
iv.
[ "i.", "ii.", "iii." ]
[ "i. UTP", "ii. GTP", "iii. ATP" ]
iii. ATP
Choose the correct answer from the options below.
[ { "content": "Hydrolysis of which of the following yields 10.5 Kcal energy?\n\ni. UTP\nii. GTP\niii. ATP\niv. Creatine phosphate", "role": "user" }, { "content": "iv. Creatine phosphate", "role": "assistant" } ]
c69008f5-f840-4998-8914-9a409dfb4fb9
A 19-year-old patient complains of primary amenorrhea. She had well developed breast and pubic hair but on examination there was absence of uterus and vagina. Likely diagnosis is : [a] Mullerian agenesis [b] XYY [c] Gonadal dysgenesis [d] Klinefelter syndrome
XYY
Mullerian agenesis
Gonadal dysgenesis
Klinefelter syndrome
1
single
Developmental defect of the Mullerian ducts resulting in the condition described as the Mayer-Rokitansky-Kuster-Hauser (MRHK) syndrome. The MRHK syndrome occurs in 1:5000-1:20,000 women at bih, and is diagnosed in approximately 1:1500 gynaecologic admissions. The clinical features include primary amenorrhoea, paial or complete absence of vagina, a wide array of uterine abnormalities, skeletal/renal and other associated abnormalities, a normal female appearance and secondary sexual characteristics and a normal 46 XX karyotype. The ovaries are anatomically and functionally normal. These patients seek medical consultation because of primary amenorrhoea or in case of presence of functional uterus (1:10 cases)--because of cyclic abdominal pain occurring as a result of occult menstruation. Pelvic ultrasonography/MRI and laparoscopy help to establish the diagnosis. Mullerian duct agenesis may result in the uterus represented by a nodule (rudimentary uterus) with hypoplastic or dimple vagina. Reference: Shaw's Textbook of gynaecology,16th edition page no 132
Gynaecology & Obstetrics
Disorders of menstruation
[a] Mullerian agenesis
[a] Mullerian agenesis [b] XYY [c] Gonadal dysgenesis [d] Klinefelter syndrome
[a]
[ "[b]", "[c]", "[d]" ]
[ "[b] XYY", "[c] Gonadal dysgenesis", "[d] Klinefelter syndrome" ]
[b] XYY
Choose the correct answer from the options below.
[ { "content": "A 19-year-old patient complains of primary amenorrhea. She had well developed breast and pubic hair but on examination there was absence of uterus and vagina. Likely diagnosis is :\n\n[a] Mullerian agenesis\n[b] XYY\n[c] Gonadal dysgenesis\n[d] Klinefelter syndrome", "role": "user" }, { "content": "[a] Mullerian agenesis", "role": "assistant" } ]
917f9982-716e-4c16-8611-87873f22877f
You are being asked to give your expe opinion as a toxicologist regarding an effective antidote for belladonna poisoning. Which of the following agents would you suggest? 1. Pilocarpine 2. Atropine 3. Neostigmine 4. Physostigmine
Neostigmine
Physostigmine
Pilocarpine
Atropine
1
single
- Atropine is obtained from atropa belladonna. - It is non selective muscarinic receptor antagonist Physostigmine is the specific antidote for poisoning with belladonna . It crosses blood-brain barrier and antagonises both central and peripheral actions. Physostigmine sometimes itself induces hypotension, arrhythmias and undesirable central effects. It is therefore employed only as a last reso. Neostigmine does not block the central effect, but is less risky.
Pharmacology
ANS
4. Physostigmine
1. Pilocarpine 2. Atropine 3. Neostigmine 4. Physostigmine
4.
[ "1.", "2.", "3." ]
[ "1. Pilocarpine", "2. Atropine", "3. Neostigmine" ]
3. Neostigmine
Choose the correct answer from the options below.
[ { "content": "You are being asked to give your expe opinion as a toxicologist regarding an effective antidote for belladonna poisoning. Which of the following agents would you suggest?\n\n1. Pilocarpine\n2. Atropine\n3. Neostigmine\n4. Physostigmine", "role": "user" }, { "content": "4. Physostigmine", "role": "assistant" } ]
15372cb0-f9d6-4afb-b9ee-bf56b45f8f44
A 52 year old male with a history of hea disease presents with sudden painless loss of vision in one eye. Examination reveals cherry red spot. Diagnosis is: 1) Diabetic retinopathy 2) Acute ischemic optic neuritis 3) Central retinal aery occlusion 4) Central retinal vein occlusion
Central retinal vein occlusion
Central retinal aery occlusion
Diabetic retinopathy
Acute ischemic optic neuritis
1
single
Central retinal aery occlusion: It occurs due to obstruction at the level of lamina cribrosa. Causes sudden painless loss of vision. Retina becomes white due to oedema & a cherry red spot is seen at the fovea. Aerioles become narrow & blood column within the retinal vessels is segmented. Resuscitation time of the human retina following retinal ischemia is 11/2 hours. Ref: Review of Ophthalmology by A.K. Khurana, 5th Edition, Page 113
Ophthalmology
null
3) Central retinal aery occlusion
1) Diabetic retinopathy 2) Acute ischemic optic neuritis 3) Central retinal aery occlusion 4) Central retinal vein occlusion
3)
[ "1)", "2)", "4)" ]
[ "1) Diabetic retinopathy", "2) Acute ischemic optic neuritis", "4) Central retinal vein occlusion" ]
4) Central retinal vein occlusion
Choose the correct answer from the options below.
[ { "content": "A 52 year old male with a history of hea disease presents with sudden painless loss of vision in one eye. Examination reveals cherry red spot. Diagnosis is:\n\n1) Diabetic retinopathy\n2) Acute ischemic optic neuritis\n3) Central retinal aery occlusion\n4) Central retinal vein occlusion", "role": "user" }, { "content": "3) Central retinal aery occlusion", "role": "assistant" } ]
ca3f0057-0329-4804-bfe7-1594c570f88a
Lower level of scapula is at the level of? (a) T6 (b) T4 (c) T7 (d) T5
T4
T5
T6
T7
3
single
The inferior angle lies over the 7th rib or the 7th intercoastal space. Reference:page no:17 - vishram singh - upper limb & thorax, 2nd edition.
Anatomy
Upper limb
(c) T7
(a) T6 (b) T4 (c) T7 (d) T5
(c)
[ "(a)", "(b)", "(d)" ]
[ "(a) T6", "(b) T4", "(d) T5" ]
(b) T4
Choose the correct answer from the options below.
[ { "content": "Lower level of scapula is at the level of?\n\n(a) T6\n(b) T4\n(c) T7\n(d) T5", "role": "user" }, { "content": "(c) T7", "role": "assistant" } ]
1e755453-494b-422d-b665-2103ce8d4129
Measles epidemic can be anticipated when proportion of suceptible children in a community 1. 40% 2. 20% 3. 80% 4. 60%
20%
40%
60%
80%
1
single
null
Social & Preventive Medicine
null
1. 40%
1. 40% 2. 20% 3. 80% 4. 60%
1.
[ "2.", "3.", "4." ]
[ "2. 20%", "3. 80%", "4. 60%" ]
2. 20%
Choose the correct answer from the options below.
[ { "content": "Measles epidemic can be anticipated when proportion of suceptible children in a community\n\n1. 40%\n2. 20%\n3. 80%\n4. 60%", "role": "user" }, { "content": "1. 40%", "role": "assistant" } ]
61e00303-9d23-4267-a808-e28c7333b0ba
The most likely diagnosis is a case of the intractable convulsions mental defect and facial nevus is- [a] Sturge Weber syndrome [b] Von-Hippen -Lindau disease [c] Tuberous sclerosis [d] Von- Reckling-Hausens disease
Sturge Weber syndrome
Tuberous sclerosis
Von-Hippen -Lindau disease
Von- Reckling-Hausens disease
0
single
Sturge Weber syndrome and Von-Reckling-Hausen disease (NF-1) have been explained earlier about other options.  Tuberous sclerosis ( Bourneville's disease) Tuberous sclerosis is characterized by : - Cutaneous lesions → Adenoma sebaceum, ash-leaf shaped hypopigmented macules, shagreen patches, depigmented nevi. Seizures Mental retardation Other features  → Calcified subependymal nodules, Subependymal giant cell astrocytoma, ependymoma, Rhabdomyomas of the heart, and angiomyomas of the kidney, liver, adrenals and pancreas. Von Hippel - Lindau syndrome This syndrome consists of Retinal, cerebellar and spinal hemangioblastoma. Renal cell carcinoma, Pheochromocytoma, benign cyst of the kidney, liver, pancreas and epididymis may also occur. Polycythemia may occur due to secretion of erythropoietin from hemangioblastoma.
Pathology
null
[a] Sturge Weber syndrome
[a] Sturge Weber syndrome [b] Von-Hippen -Lindau disease [c] Tuberous sclerosis [d] Von- Reckling-Hausens disease
[a]
[ "[b]", "[c]", "[d]" ]
[ "[b] Von-Hippen -Lindau disease", "[c] Tuberous sclerosis", "[d] Von- Reckling-Hausens disease" ]
[d] Von- Reckling-Hausens disease
Choose the correct answer from the options below.
[ { "content": "The most likely diagnosis is a case of the intractable convulsions mental defect and facial nevus is-\n\n[a] Sturge Weber syndrome\n[b] Von-Hippen -Lindau disease\n[c] Tuberous sclerosis\n[d] Von- Reckling-Hausens disease", "role": "user" }, { "content": "[a] Sturge Weber syndrome", "role": "assistant" } ]
8707f715-f2c8-42e6-a2b9-6a939d92baf7
A 60-year-old male Suresh is hospitalized with muscle pain, fatigue and dark urine. His past medical history is significant for stable angina. The patient's medications include atenolol, atorvastatin, and aspirin. His urine dipstick test is positive for blood but urine microscopy did not reveal RBCs in the urine. Serum creatinine kinase was significantly raised in this person. The addition of which of the following medications is most likely to have precipitated this patient's condition? A) Rifampin B) Amikacin C) Griseofulvin D) Erythromycin
Erythromycin
Rifampin
Griseofulvin
Amikacin
0
single
Diagnosis in this condition is Rhabdomyolysis suggested by myoglobinuria (red coloured urine without RBCs) and raised creatinine kinase levels. Statins can cause serious s/e like myopathy and hepatitis. Most statins are metabolized by cytochrome P-450 3A4, with the exception of pravastatin. Concomitant administration of drugs that inhibit statin metabolism (e.g. macrolides- Erythromycin) is associated with increased incidence of statin induced myopathy and rhabdomyolysis. Acute renal failure is a possible sequelae of rhabdomyolysis.
Pharmacology
Hematology and CVS
D) Erythromycin
A) Rifampin B) Amikacin C) Griseofulvin D) Erythromycin
D)
[ "A)", "B)", "C)" ]
[ "A) Rifampin", "B) Amikacin", "C) Griseofulvin" ]
A) Rifampin
Choose the correct answer from the options below.
[ { "content": "A 60-year-old male Suresh is hospitalized with muscle pain, fatigue and dark urine. His past medical history is significant for stable angina. The patient's medications include atenolol, atorvastatin, and aspirin. His urine dipstick test is positive for blood but urine microscopy did not reveal RBCs in the urine. Serum creatinine kinase was significantly raised in this person. The addition of which of the following medications is most likely to have precipitated this patient's condition?\n\nA) Rifampin\nB) Amikacin\nC) Griseofulvin\nD) Erythromycin", "role": "user" }, { "content": "D) Erythromycin", "role": "assistant" } ]
80f33d11-5fbd-4d22-8ef5-fb0470458d20
The period from acquiring inrfection to maximum infectivity is called as- (1) Incubation period (2) Generation time (3) Secondary interval (4) Serial time
Generation time
Serial time
Incubation period
Secondary interval
0
multi
In general, generation time is roughly equal to incubation period. But these 2 terms are not the same. The time of maximum communicability may precede or follow the incubation period. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 108
Social & Preventive Medicine
Epidemiology
(2) Generation time
(1) Incubation period (2) Generation time (3) Secondary interval (4) Serial time
(2)
[ "(1)", "(3)", "(4)" ]
[ "(1) Incubation period", "(3) Secondary interval", "(4) Serial time" ]
(4) Serial time
Choose the correct answer from the options below.
[ { "content": "The period from acquiring inrfection to maximum infectivity is called as-\n\n(1) Incubation period\n(2) Generation time\n(3) Secondary interval\n(4) Serial time", "role": "user" }, { "content": "(2) Generation time", "role": "assistant" } ]
a58e058e-02b3-4cc7-be57-318d9874fba1
Collapsing glomerulopathy is seen in? (A) Tuberculosis (B) HIV (C) IgA nephropathy (D) Post streptococcal GN
Post streptococcal GN
HIV
IgA nephropathy
Tuberculosis
1
single
Ans. is 'b' i.e., HIV Collapsing glomerulopathy:* It is a morphological variant of FSGS. Characterized by collapse and sclerosis of the entire glomerular tuft in addition to the usual FSGS lesions. A characteristic feature is proliferation and hypertrophy of glomerular visceral epithelial cells (podocytes). There is prominent tubular injury with formation of microcystes. It is the most characteristic lesion of HIV nephropathy.
Pathology
Kidney
(B) HIV
(A) Tuberculosis (B) HIV (C) IgA nephropathy (D) Post streptococcal GN
(B)
[ "(A)", "(C)", "(D)" ]
[ "(A) Tuberculosis", "(C) IgA nephropathy", "(D) Post streptococcal GN" ]
(A) Tuberculosis
Choose the correct answer from the options below.
[ { "content": "Collapsing glomerulopathy is seen in?\n\n(A) Tuberculosis\n(B) HIV\n(C) IgA nephropathy\n(D) Post streptococcal GN", "role": "user" }, { "content": "(B) HIV", "role": "assistant" } ]
c9f18487-4543-45ab-936f-1e19d8e256d5
Most common site of Morgagni hernia: [1] Right anterior [2] Left posterior [3] Left anterior [4] Right posterior
Right anterior
Right posterior
Left anterior
Left posterior
0
single
Right anterior Repeat from Nov 06 Morgagni hernia is a rare form of cong. diaphragmatic hernia occurring through foramen of Morgagni or space of Larrey i.e. space between the sternal and costal origins of the diaphragm) It is more common on right side. Usually it is asymptomatic Most common viscera to herniate through space of Morgagni is transverse colon (Bailey & Love, 24/e, p 873) Also know Superior epigastric vessels pass through foramen of Morgagni
Surgery
null
[1] Right anterior
[1] Right anterior [2] Left posterior [3] Left anterior [4] Right posterior
[1]
[ "[2]", "[3]", "[4]" ]
[ "[2] Left posterior", "[3] Left anterior", "[4] Right posterior" ]
[4] Right posterior
Choose the correct answer from the options below.
[ { "content": "Most common site of Morgagni hernia:\n\n[1] Right anterior\n[2] Left posterior\n[3] Left anterior\n[4] Right posterior", "role": "user" }, { "content": "[1] Right anterior", "role": "assistant" } ]
9c72705a-6d3a-4741-b030-26399f390e40
All of the following are true of Eales disease except – [A] Retinal detachment [B] Optic neuritis [C] Occurs in the young [D] Vitreous hemorrhage is present
Occurs in the young
Vitreous hemorrhage is present
Retinal detachment
Optic neuritis
3
multi
Eale's disease is characterized by recurrent bilateral vitreous hemorrhage in young adult (20-30 yrs) males. Tractional retinal detachment may occur as a complication. Optic neuritis is not a feature of Eale's disease.
Ophthalmology
null
[B] Optic neuritis
[A] Retinal detachment [B] Optic neuritis [C] Occurs in the young [D] Vitreous hemorrhage is present
[B]
[ "[A]", "[C]", "[D]" ]
[ "[A] Retinal detachment", "[C] Occurs in the young", "[D] Vitreous hemorrhage is present" ]
[A] Retinal detachment
Choose the correct answer from the options below.
[ { "content": "All of the following are true of Eales disease except –\n\n[A] Retinal detachment\n[B] Optic neuritis\n[C] Occurs in the young\n[D] Vitreous hemorrhage is present", "role": "user" }, { "content": "[B] Optic neuritis", "role": "assistant" } ]
b495f2ce-4022-4c43-b232-7fc500e4d0dd
A 35 year old lady Malti has unilateral headache, nausea, vomiting and visual blurring. The diagnosis is - (A) Glaucoma (B) Subarachnoid haemorrhage (C) Cluster headache (D) Posterior fossa cyst
Cluster headache
Glaucoma
Subarachnoid haemorrhage
Posterior fossa cyst
1
single
null
Medicine
null
(A) Glaucoma
(A) Glaucoma (B) Subarachnoid haemorrhage (C) Cluster headache (D) Posterior fossa cyst
(A)
[ "(B)", "(C)", "(D)" ]
[ "(B) Subarachnoid haemorrhage", "(C) Cluster headache", "(D) Posterior fossa cyst" ]
(C) Cluster headache
Choose the correct answer from the options below.
[ { "content": "A 35 year old lady Malti has unilateral headache, nausea, vomiting and visual blurring. The diagnosis is -\n\n(A) Glaucoma\n(B) Subarachnoid haemorrhage\n(C) Cluster headache\n(D) Posterior fossa cyst", "role": "user" }, { "content": "(A) Glaucoma", "role": "assistant" } ]
832534dc-8c77-4f76-ad37-38d8721c46f3
To obtain best long term result, which of the following procedures for augmentation genioplasty is recommended: I. Pedicled horizontal sliding osteotomy II. Injection of silastic gel III. Insertion of silastic rubber implant IV. On lay bone graft
On lay bone graft
Injection of silastic gel
Insertion of silastic rubber implant
Pedicled horizontal sliding osteotomy
3
single
null
Surgery
null
I. Pedicled horizontal sliding osteotomy
I. Pedicled horizontal sliding osteotomy II. Injection of silastic gel III. Insertion of silastic rubber implant IV. On lay bone graft
I.
[ "II.", "III.", "IV." ]
[ "II. Injection of silastic gel", "III. Insertion of silastic rubber implant", "IV. On lay bone graft" ]
IV. On lay bone graft
Choose the correct answer from the options below.
[ { "content": "To obtain best long term result, which of the\nfollowing procedures for augmentation genioplasty is recommended:\n\nI. Pedicled horizontal sliding osteotomy\nII. Injection of silastic gel\nIII. Insertion of silastic rubber implant\nIV. On lay bone graft", "role": "user" }, { "content": "I. Pedicled horizontal sliding osteotomy", "role": "assistant" } ]
817bb345-887d-425f-bc3e-29deb71eeb2e
Absent/hypoplastic radius is a feature of? (A) Holt-Oram syndrome (B) Chondrodysplasia punctata (C) CCD (D) Spondyloepiphyseal dysplasia
Holt-Oram syndrome
Spondyloepiphyseal dysplasia
Chondrodysplasia punctata
CCD
0
single
Ans ARadial hypoplasia more commonly a sporadic mutation rather than an inherited condition. In case of an inherited condition, several syndromes are known such as the Holt- Oram syndrome, VATER syndrome, Fanconi anemia and TAR syndrome. Other possible causes are an injury to the apical ectodermal ridge during upper limb development, intrauterine compression & maternal drug use (thalidomide).
Radiology
Skeletal System
(A) Holt-Oram syndrome
(A) Holt-Oram syndrome (B) Chondrodysplasia punctata (C) CCD (D) Spondyloepiphyseal dysplasia
(A)
[ "(B)", "(C)", "(D)" ]
[ "(B) Chondrodysplasia punctata", "(C) CCD", "(D) Spondyloepiphyseal dysplasia" ]
(C) CCD
Choose the correct answer from the options below.
[ { "content": "Absent/hypoplastic radius is a feature of?\n\n(A) Holt-Oram syndrome\n(B) Chondrodysplasia punctata\n(C) CCD\n(D) Spondyloepiphyseal dysplasia", "role": "user" }, { "content": "(A) Holt-Oram syndrome", "role": "assistant" } ]
aebe6054-dc3e-461b-9e64-9d9f36279664
A 28 year old boy met with on accident and sustained severe crush injury. He is most likely to develop: A) Acute Renal Failure B) Acute Myocardial Infarction C) Hypercalcemia D) Hypophosphatemia
Acute Renal Failure
Hypophosphatemia
Hypercalcemia
Acute Myocardial Infarction
0
single
Answer is A (Acute Renal Failure): Acute Renal failure is an established complication of crush syndrome. Acute Renal Failure is usually caused by a combination of hypovolemia and release of nephrotoxic substances into the circulation such as myoglobin Crush syndrome is associated with hvpocalcemia and hvperphosphatemia Note Crush syndrome is associated with Hypocalcemia and not hypercalcemia. of calcium into muscle calls through leaky sarcolemmal membranes.
Medicine
null
A) Acute Renal Failure
A) Acute Renal Failure B) Acute Myocardial Infarction C) Hypercalcemia D) Hypophosphatemia
A)
[ "B)", "C)", "D)" ]
[ "B) Acute Myocardial Infarction", "C) Hypercalcemia", "D) Hypophosphatemia" ]
B) Acute Myocardial Infarction
Choose the correct answer from the options below.
[ { "content": "A 28 year old boy met with on accident and sustained severe crush injury. He is most likely to develop:\n\nA) Acute Renal Failure\nB) Acute Myocardial Infarction\nC) Hypercalcemia\nD) Hypophosphatemia", "role": "user" }, { "content": "A) Acute Renal Failure", "role": "assistant" } ]
17cf6c67-b578-4d95-9b25-dc7b169db46f
Vaccines contraindicated in HIV positive child - i. Rabies ii. MMR iii. Influenza iv. OPV
OPV
MMR
Rabies
Influenza
0
single
All live attenuated vaccines are contraindicated in HIV, as it can precipitate the infection due to imnunosuporessio. BCG,OPV ,measles are contraindicated in HIV Reference: Essential pediatrics,op ghai,9 th edition,pg no: 188 189
Pediatrics
Infectious disease
iv. OPV
i. Rabies ii. MMR iii. Influenza iv. OPV
iv.
[ "i.", "ii.", "iii." ]
[ "i. Rabies", "ii. MMR", "iii. Influenza" ]
iii. Influenza
Choose the correct answer from the options below.
[ { "content": "Vaccines contraindicated in HIV positive child -\n\ni. Rabies\nii. MMR\niii. Influenza\niv. OPV", "role": "user" }, { "content": "iv. OPV", "role": "assistant" } ]
47b51eac-a25a-4ee0-9864-0b2c8e48f7d4
Takayam test is used for ? 1. None of the above 2. To know the species 3. For blood grouping 4. To know the nature of stain
To know the nature of stain
To know the species
For blood grouping
None of the above
0
multi
Ans. is 'a' i.e., To know the nature of stain It is a microchemical test to know the nature of stain.Microchemical tests :These tests are based on propey of haem pa of hemoglobin to form characteristic coloured crystals.Teichmann's haemin crystal testTakayama hemochromogen crystal testLuminal spray test : It is especially useful in old obscure blood stains
Forensic Medicine
null
4. To know the nature of stain
1. None of the above 2. To know the species 3. For blood grouping 4. To know the nature of stain
4.
[ "1.", "2.", "3." ]
[ "1. None of the above", "2. To know the species", "3. For blood grouping" ]
2. To know the species
Choose the correct answer from the options below.
[ { "content": "Takayam test is used for ?\n\n1. None of the above\n2. To know the species\n3. For blood grouping\n4. To know the nature of stain", "role": "user" }, { "content": "4. To know the nature of stain", "role": "assistant" } ]
3b4752a3-eff0-4d82-bbcf-9ce7993b94d1
Grievous hu comes under which section of IPC? (1) Section 320 (2) Section 319 (3) Section 324 (4) Section 326
Section 319
Section 320
Section 324
Section 326
1
single
Section 320 REF: Textbook of Forensic Medicine and Toxicology by Nagesh Kumar Rao Page 259 Section 320: Grievous hu The following kinds of hu only are designated as "grievous" Emasculation Permanent privation of the sight of either eye Permanent privation of the hearing of either ear Privation of any member or joint Destruction or permanent impairing of the powers of any member or joint Permanent disfiguration of the head or face Fracture or dislocation of a bone or tooth Any hu which endangers life or which causes the sufferer to be during the space of twenty days in severe bodily pain, or unable to follow his ordinary pursuits.
Forensic Medicine
null
(1) Section 320
(1) Section 320 (2) Section 319 (3) Section 324 (4) Section 326
(1)
[ "(2)", "(3)", "(4)" ]
[ "(2) Section 319", "(3) Section 324", "(4) Section 326" ]
(2) Section 319
Choose the correct answer from the options below.
[ { "content": "Grievous hu comes under which section of IPC?\n\n(1) Section 320\n(2) Section 319\n(3) Section 324\n(4) Section 326", "role": "user" }, { "content": "(1) Section 320", "role": "assistant" } ]
0d4d4dfe-7061-4678-afab-a43182634a00
Drug used in remodeling of hea in congestive cardiac failure are all EXCEPT - (1) Digoxin (2) Beta blocker (3) ACE inhibitor (4) Aldosterone antagonist
Beta blocker
ACE inhibitor
Digoxin
Aldosterone antagonist
2
multi
Ans. is 'c' i.e., Digoxin
Pharmacology
null
(1) Digoxin
(1) Digoxin (2) Beta blocker (3) ACE inhibitor (4) Aldosterone antagonist
(1)
[ "(2)", "(3)", "(4)" ]
[ "(2) Beta blocker", "(3) ACE inhibitor", "(4) Aldosterone antagonist" ]
(2) Beta blocker
Choose the correct answer from the options below.
[ { "content": "Drug used in remodeling of hea in congestive cardiac failure are all EXCEPT -\n\n(1) Digoxin\n(2) Beta blocker\n(3) ACE inhibitor\n(4) Aldosterone antagonist", "role": "user" }, { "content": "(1) Digoxin", "role": "assistant" } ]
3c446c65-404b-4f15-ac36-fc98764b437a
The Myer-Cotton grading system is used for: [1] Tonsillitis [2] None of the above [3] Sinisitis [4] Subglottic stenosis
Subglottic stenosis
Tonsillitis
Sinisitis
None of the above
0
multi
The Myer-Cotton grading system describes the severity of stenosis according to the percentage of subglottic stenosis present. The percentage is calculated by measuring the largest sized endotracheal tube that can be passed through the subglottis and comparing this with the age-appropriate tube size for the child
ENT
null
[4] Subglottic stenosis
[1] Tonsillitis [2] None of the above [3] Sinisitis [4] Subglottic stenosis
[4]
[ "[1]", "[2]", "[3]" ]
[ "[1] Tonsillitis", "[2] None of the above", "[3] Sinisitis" ]
[2] None of the above
Choose the correct answer from the options below.
[ { "content": "The Myer-Cotton grading system is used for:\n\n[1] Tonsillitis\n[2] None of the above\n[3] Sinisitis\n[4] Subglottic stenosis", "role": "user" }, { "content": "[4] Subglottic stenosis", "role": "assistant" } ]
f0fc71dd-c91a-4b85-a967-48257cbb0057
Most common presentation of cardiac lupus? (A) Myocarditis (B) Aortic regurgitation (C) Libman sacks endocarditis (D) Pericarditis
Myocarditis
Pericarditis
Aortic regurgitation
Libman sacks endocarditis
1
single
Ans. is 'b' i.e., Pericarditis Cardiopulmonary involvement in SLEo Pleurisy, pericarditis, effusions.o Myocarditis, endocarditiso Lupus pneumonitiso Coronary artery disease:# Interstitial fibrosis# Pulmonaiy hypertension# Shrinking lung syndrome# ARDS, hemorrhage
Medicine
Cardiomyopathy & Pericarditis
(D) Pericarditis
(A) Myocarditis (B) Aortic regurgitation (C) Libman sacks endocarditis (D) Pericarditis
(D)
[ "(A)", "(B)", "(C)" ]
[ "(A) Myocarditis", "(B) Aortic regurgitation", "(C) Libman sacks endocarditis" ]
(A) Myocarditis
Choose the correct answer from the options below.
[ { "content": "Most common presentation of cardiac lupus?\n\n(A) Myocarditis\n(B) Aortic regurgitation\n(C) Libman sacks endocarditis\n(D) Pericarditis", "role": "user" }, { "content": "(D) Pericarditis", "role": "assistant" } ]
b562d110-bd6c-4d6d-92e3-58b1ded1cf8a
Which one of the following is not used as a tumor marker in testicular tumors? A) LDH B) CEA C) HCG D) AFP
AFP
LDH
HCG
CEA
3
single
CEA is an oncofetal antigen and may be used as a tumor marker in adenocarcinoma of colon, pancreas, lung, breast, and ovary. However not used as a marker for germ cell tumorsTumor markers for germ cell tumors:Alpha-fetoprotein seen in non-seminomatous germ cell tumorsHCG: 1. non-seminomatous germ cell tumors; 2. Non-seminomatous germ cell tumorsOthers:LDHPlacental alkaline phosphatase(Ref: Harrison's 18/e p652, table 81-6)
Medicine
All India exam
B) CEA
A) LDH B) CEA C) HCG D) AFP
B)
[ "A)", "C)", "D)" ]
[ "A) LDH", "C) HCG", "D) AFP" ]
C) HCG
Choose the correct answer from the options below.
[ { "content": "Which one of the following is not used as a tumor marker in testicular tumors?\n\nA) LDH\nB) CEA\nC) HCG\nD) AFP", "role": "user" }, { "content": "B) CEA", "role": "assistant" } ]
3843d62c-0290-4f6d-bdc4-f4a8fa22a710
Which one is not true regarding pseudocyst of pancreas i. Cystogastrostomy is the ideal T/t ii. Increase level of amylase iii. Percutaneus aspiration is the T/t iv. Epigastric mass
Increase level of amylase
Epigastric mass
Cystogastrostomy is the ideal T/t
Percutaneus aspiration is the T/t
3
multi
Percutaneous aspiration is preferred only in cases of infected cyst and abscesses, other wise internal drainage is the t/t of choice. Epigastric mass is the main symptom of the pseudocyst. Increased level of amylase is usually elevated with pancreatic pseudocysts Ref - Srb's manual of surgery 5e p690
Anatomy
G.I.T
iii. Percutaneus aspiration is the T/t
i. Cystogastrostomy is the ideal T/t ii. Increase level of amylase iii. Percutaneus aspiration is the T/t iv. Epigastric mass
iii.
[ "i.", "ii.", "iv." ]
[ "i. Cystogastrostomy is the ideal T/t", "ii. Increase level of amylase", "iv. Epigastric mass" ]
i. Cystogastrostomy is the ideal T/t
Choose the correct answer from the options below.
[ { "content": "Which one is not true regarding pseudocyst of pancreas\n\ni. Cystogastrostomy is the ideal T/t\nii. Increase level of amylase\niii. Percutaneus aspiration is the T/t\niv. Epigastric mass", "role": "user" }, { "content": "iii. Percutaneus aspiration is the T/t", "role": "assistant" } ]
d39dd169-b4ef-4356-9f6d-95432942d02b
Sex worker with discharging ulcer, gram negative diplococci & growth on modified Thayer martin media. Diagnosis - i. Chaneroid ii. N. gonococci iii. LGV iv. Syphilis
N. gonococci
Syphilis
LGV
Chaneroid
0
single
Ans. is 'a' i.e., N. gonococcio Information in this question are -Gram negative diplococci.Growth on modified Thayer-martin media.o Neisseria gonorrhoeae is a gram negative diplococci and Thayer-martin medium is the selective medium for gonococci.Lab diagnosis of gonorrheao Urethral discharge is the most important specimen.o Transport media* It processing is to occur within 6 hrs-Stuart medium or Amies medium.* If processing is to occur > 6 hrs-JEMBEC or Gono - Pak system (media with self - contained CO2-generating system).o Cluture media* In acute cases-Chocolate agar or Muller - Hinton agar.* In chronic cases-Selective medium - Thayer martin medium.o Normally the diagnosis of gonorrhoea is made by isolating the organism in culture.o It may not be possible to obtain gonococci in culture from some chronic cases or from patients with metastatic lesions such as arthritis. Serological test may be of value in such instances.o In serological tests antibodies to gonococcal pili, LPS and outer membrane proteins are detected.o Various tests are -1) Complement fixation text4) Immunofluorescence7) Immunobloting2) Precipitation5) Radioimmunoassay 3) Passive agglutination6) Enzyme - linked immunosorbent assay (ELISA) However, no serological test has been found useful for routine diagnostic procedure.
Skin
S.T.D.
ii. N. gonococci
i. Chaneroid ii. N. gonococci iii. LGV iv. Syphilis
ii.
[ "i.", "iii.", "iv." ]
[ "i. Chaneroid", "iii. LGV", "iv. Syphilis" ]
i. Chaneroid
Choose the correct answer from the options below.
[ { "content": "Sex worker with discharging ulcer, gram negative diplococci & growth on modified Thayer martin media. Diagnosis -\n\ni. Chaneroid\nii. N. gonococci\niii. LGV\niv. Syphilis", "role": "user" }, { "content": "ii. N. gonococci", "role": "assistant" } ]
4492b962-da6e-4c98-97d2-d24f50ab6900
Human immunoglobulin is given in all except 1. Measles 2. Hepatitis B 3. chickenpox 4. Rabies
Measles
Hepatitis B
Rabies
chickenpox
0
multi
null
Social & Preventive Medicine
null
1. Measles
1. Measles 2. Hepatitis B 3. chickenpox 4. Rabies
1.
[ "2.", "3.", "4." ]
[ "2. Hepatitis B", "3. chickenpox", "4. Rabies" ]
3. chickenpox
Choose the correct answer from the options below.
[ { "content": "Human immunoglobulin is given in all except\n\n1. Measles\n2. Hepatitis B\n3. chickenpox\n4. Rabies", "role": "user" }, { "content": "1. Measles", "role": "assistant" } ]
69baf63c-32f8-4908-ac08-370cdeae84b6
A cystic, painless swelling along the upper border of sternocleidomastoid muscle is most likely to be: March 2013 (b) a) Branchial fistula b) Branchial cyst c) Thyroglossal cyst d) Cystic hygroma
Thyroglossal cyst
Branchial cyst
Cystic hygroma
Branchial fistula
1
single
Ans. B i.e. Branchial cyst
Surgery
null
b) Branchial cyst
a) Branchial fistula b) Branchial cyst c) Thyroglossal cyst d) Cystic hygroma
b)
[ "a)", "c)", "d)" ]
[ "a) Branchial fistula", "c) Thyroglossal cyst", "d) Cystic hygroma" ]
c) Thyroglossal cyst
Choose the correct answer from the options below.
[ { "content": "A cystic, painless swelling along the upper border of sternocleidomastoid muscle is most likely to be: March 2013 (b)\n\na) Branchial fistula\nb) Branchial cyst\nc) Thyroglossal cyst\nd) Cystic hygroma", "role": "user" }, { "content": "b) Branchial cyst", "role": "assistant" } ]
b94c351a-1e91-4f40-92ad-8a85428eff30
Identity the structure in the given chest X-ray: A) Right-Costophrenic angle B) Left-Costophrenic angle C) Left-Cardiophrenic angle D) Right-Cardiophrenic angle
Left-Costophrenic angle
Left-Cardiophrenic angle
Right-Costophrenic angle
Right-Cardiophrenic angle
1
single
Ans. b. Left-Cardiophrenic angle
Radiology
Respiratory System
C) Left-Cardiophrenic angle
A) Right-Costophrenic angle B) Left-Costophrenic angle C) Left-Cardiophrenic angle D) Right-Cardiophrenic angle
C)
[ "A)", "B)", "D)" ]
[ "A) Right-Costophrenic angle", "B) Left-Costophrenic angle", "D) Right-Cardiophrenic angle" ]
B) Left-Costophrenic angle
Choose the correct answer from the options below.
[ { "content": "Identity the structure in the given chest X-ray:\n\nA) Right-Costophrenic angle\nB) Left-Costophrenic angle\nC) Left-Cardiophrenic angle\nD) Right-Cardiophrenic angle", "role": "user" }, { "content": "C) Left-Cardiophrenic angle", "role": "assistant" } ]
be5141ed-acfa-4700-878c-2b1609f4eb88
Which of the following is the only intrinsic muscle of larynx that lies outside the laryngeal framework 1) Lateral cricoarytenoid 2) Cricothyroid 3) Superior constrictor 4) Cricopharyngeus
Cricopharyngeus
Superior constrictor
Cricothyroid
Lateral cricoarytenoid
2
single
Cricothyroid muscle is the only intrinsic muscle which is supplied by external laryngeal nerve and lies outside the laryngeal framework. Ref:- Dhingra; pg num:-284
ENT
Larynx
2) Cricothyroid
1) Lateral cricoarytenoid 2) Cricothyroid 3) Superior constrictor 4) Cricopharyngeus
2)
[ "1)", "3)", "4)" ]
[ "1) Lateral cricoarytenoid", "3) Superior constrictor", "4) Cricopharyngeus" ]
1) Lateral cricoarytenoid
Choose the correct answer from the options below.
[ { "content": "Which of the following is the only intrinsic muscle of larynx that lies outside the laryngeal framework\n\n1) Lateral cricoarytenoid\n2) Cricothyroid\n3) Superior constrictor\n4) Cricopharyngeus", "role": "user" }, { "content": "2) Cricothyroid", "role": "assistant" } ]
8316ffdf-80d4-4e54-a136-a98d47df03b0
True regarding primary sclerosing cholangitis associated with ulcerative colitis are all of the following except I. Primary sclerosing cholangitis resolves after total colectomy II. May have raised levels of alkaline phosphatase III. Biliary cirrhosis is a known complication IV. Increased risk of hilar cholangiocarcinoma
Biliary cirrhosis is a known complication
Increased risk of hilar cholangiocarcinoma
May have raised levels of alkaline phosphatase
Primary sclerosing cholangitis resolves after total colectomy
3
multi
Patients with PSC and UC typically have a more quiescent disease course The risk for colon cancer in these patients is up to five times greater than in patients with ulcerative colitis alone. These tumors are more likely to arise proximal to the splenic flexure PSC is progressive and ultimately fatal unless liver transplantation is undeaken. Colectomy has no effect on the course of PSC Ref: Sabiston 20th edition Pgno :1508-1509
Anatomy
G.I.T
I. Primary sclerosing cholangitis resolves after total colectomy
I. Primary sclerosing cholangitis resolves after total colectomy II. May have raised levels of alkaline phosphatase III. Biliary cirrhosis is a known complication IV. Increased risk of hilar cholangiocarcinoma
I.
[ "II.", "III.", "IV." ]
[ "II. May have raised levels of alkaline phosphatase", "III. Biliary cirrhosis is a known complication", "IV. Increased risk of hilar cholangiocarcinoma" ]
IV. Increased risk of hilar cholangiocarcinoma
Choose the correct answer from the options below.
[ { "content": "True regarding primary sclerosing cholangitis associated with ulcerative colitis are all of the following except\n\nI. Primary sclerosing cholangitis resolves after total colectomy\nII. May have raised levels of alkaline phosphatase\nIII. Biliary cirrhosis is a known complication\nIV. Increased risk of hilar cholangiocarcinoma", "role": "user" }, { "content": "I. Primary sclerosing cholangitis resolves after total colectomy", "role": "assistant" } ]
d444109d-2859-4130-86da-acc80bf71cbc
Ophthalmia neonatorum within first 48 hours of birth is caused by [a] Adenovirus [b] Chlamydia trachomatis [c] Neiserria gonorhoeae [d] Candida albicans
Adenovirus
Neiserria gonorhoeae
Candida albicans
Chlamydia trachomatis
1
single
Ans. b (Neisseria gonorrheae) (Ref: Parson's, 18th ed/140)DIFFERENTIAL DIAGNOSIS OF NEONATAL CONJUNCTIVITIS (OPHTHALMIA NEONATORUM)CauseOnsetFindingsCytology&lab tests(1)Toxic AgNO3- Silver nitrate (Crede's prophylaxis)Within hoursHyperemiaSlight watery to mucoid discharge. Negative culture(2)Gonococci (gonococcal conjunctivitis)2nd-4th day of lifeAcute purulent conjunctivitisIntracellular gram-negative diplococci.Positive culture on blood and chocolate agar(3)Other bacteria (Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumoniae; Haemophilus)4th-5th day of lifeMucopurulent conjunctivitisCulture on bloodagar(4)Chlamydia (inclusion conjunctMtis)... most common5th-14th day of lifeMucopurulent conjunctivitisGiemsa-positive cytoplasmic inclusion bodies in epithelial cells.Negative culture.(5)Herpes simplex virus5th-7th day of lifeWatery blepharoconjunctivitis. Corneal involvement.Systemic manifestations.Multinucleated gaint cells, cytoplasmic inclusion bodies.Negative cultureEducational Points:Intact corneal epithelium cannot be penetrated b\ any organism EXCEPT-# Neisseria gonorrhoeae# Neisseria meningitides# Cornybacterium diphtheriaeConjunctivitis FeaturesAcute mucopurulent conjunctivitis# Staph, is commonest causative organism.Ophthalmia neonatorum# Chlamydia is most common causative organism (7-10 days)# Presents at birth/in a hour of birth (Chemical)# Treatment is Credes prophylaxis with 1% silver nitrateLigneous conjunctivitis# Membranous but repeated conjunctivitisAngular conjunctivitis# Caused by Moraxella. Treatment is zinc oxideFollicular conjunctivitis# Trachoma, drug induced,New Castle's conjunctivitis# Epidemic keratoconjunctivitis sicca (adenovirus)Acute herpetic conjunctivitis# occurs in young children infected from contagion of carrierVernal conjunctivitis (Spring catarrh)# Bulbar and palpebral conjunctivitis# Bilateral and recurrent# Ropy discharge# 'Cobble stone' palpebral conjunctiva# Gaint papilla # Horner-Trantas spots# Maxwell-Lion sign# Pseudogerontoxon# Treatment with steroids, acetyl cysteine and topical NSAIDEducational point:# Sulphacetamide eye drops used for ophthalmia neonatorum.
Ophthalmology
Conjuctiva
[c] Neiserria gonorhoeae
[a] Adenovirus [b] Chlamydia trachomatis [c] Neiserria gonorhoeae [d] Candida albicans
[c]
[ "[a]", "[b]", "[d]" ]
[ "[a] Adenovirus", "[b] Chlamydia trachomatis", "[d] Candida albicans" ]
[b] Chlamydia trachomatis
Choose the correct answer from the options below.
[ { "content": "Ophthalmia neonatorum within first 48 hours of birth is caused by\n\n[a] Adenovirus\n[b] Chlamydia trachomatis\n[c] Neiserria gonorhoeae\n[d] Candida albicans", "role": "user" }, { "content": "[c] Neiserria gonorhoeae", "role": "assistant" } ]
bbf97527-6ff2-48be-b959-fc8f1b66164d
In pregnant diabetic intrauterine moality increases after the week of gestation : a. 30th b. 36th c. 25th d. 40th
30th
40th
36th
25th
1
single
40th
Gynaecology & Obstetrics
null
d. 40th
a. 30th b. 36th c. 25th d. 40th
d.
[ "a.", "b.", "c." ]
[ "a. 30th", "b. 36th", "c. 25th" ]
b. 36th
Choose the correct answer from the options below.
[ { "content": "In pregnant diabetic intrauterine moality increases after the week of gestation :\n\na. 30th\nb. 36th\nc. 25th\nd. 40th", "role": "user" }, { "content": "d. 40th", "role": "assistant" } ]
5b91ea13-60b6-40cc-a919-0a889105b564
The formation of which of the following does not represent normal physiological process of dentin formation: i. Secondary dentin and circumpulpal dentin ii. Tertiary dentin and sclerotic dentin iii. Primary and secondary dentin iv. All of the above
Primary and secondary dentin
Secondary dentin and circumpulpal dentin
Tertiary dentin and sclerotic dentin
All of the above
2
multi
null
Dental
null
ii. Tertiary dentin and sclerotic dentin
i. Secondary dentin and circumpulpal dentin ii. Tertiary dentin and sclerotic dentin iii. Primary and secondary dentin iv. All of the above
ii.
[ "i.", "iii.", "iv." ]
[ "i. Secondary dentin and circumpulpal dentin", "iii. Primary and secondary dentin", "iv. All of the above" ]
i. Secondary dentin and circumpulpal dentin
Choose the correct answer from the options below.
[ { "content": "The formation of which of the following does not represent normal physiological process of dentin formation:\n\ni. Secondary dentin and circumpulpal dentin\nii. Tertiary dentin and sclerotic dentin\niii. Primary and secondary dentin\niv. All of the above", "role": "user" }, { "content": "ii. Tertiary dentin and sclerotic dentin", "role": "assistant" } ]
9bd96247-bb26-44e4-9691-9097d710cbef
Drug of choice for infantile spasm is – [A] Vigabatrin [B] Carbamazepine [C] ACTH [D] Ethosuximide
Vigabatrin
ACTH
Ethosuximide
Carbamazepine
0
single
Myoclonic epilepsy may be Infantile spasm or Infantile myoclonus or West syndrome Juvenile myoclonic epilepsy Infantile spasm (Infantile mvoclonus or west syndrome) The onset is usually between 3-8 months of life It is characterized by a triad of - i) Salaam spells (sudden dropping of the head & flexion of arms) ii) Mental retardation iii) Hypsarrhythmic pattern of EEG (diffuse high voltage slow spike and chaotic activity) The spasm occurs in clusters usually on waking. Prognosis for normal mental development is poor. Treatment of infantile myoclonus ACTH and corticosteroids are given for 2-12 weeks, depending upon response. Vigabatrin is the DOC Now.
Pediatrics
null
[A] Vigabatrin
[A] Vigabatrin [B] Carbamazepine [C] ACTH [D] Ethosuximide
[A]
[ "[B]", "[C]", "[D]" ]
[ "[B] Carbamazepine", "[C] ACTH", "[D] Ethosuximide" ]
[C] ACTH
Choose the correct answer from the options below.
[ { "content": "Drug of choice for infantile spasm is –\n\n[A] Vigabatrin\n[B] Carbamazepine\n[C] ACTH\n[D] Ethosuximide", "role": "user" }, { "content": "[A] Vigabatrin", "role": "assistant" } ]
6e1263bf-4a76-47f9-aaf0-f11fbd8fdf32
A patient underwent Bhadrenalectomy in views of B/L pheochromocytoma 1 day later developed lethargy fatigue low BP and pulse normal No signs of volume deficit likely course (a) DI (b) SIADH (c) Addisonian Crisis (d) Cerebral salt wasting DISEASE
Addisonian Crisis
SIADH
DI
Cerebral salt wasting DISEASE
0
single
ref harissons 21st ed
Medicine
Haematology
(c) Addisonian Crisis
(a) DI (b) SIADH (c) Addisonian Crisis (d) Cerebral salt wasting DISEASE
(c)
[ "(a)", "(b)", "(d)" ]
[ "(a) DI", "(b) SIADH", "(d) Cerebral salt wasting DISEASE" ]
(a) DI
Choose the correct answer from the options below.
[ { "content": "A patient underwent Bhadrenalectomy in views of B/L pheochromocytoma 1 day later developed lethargy fatigue low BP and pulse normal No signs of volume deficit likely course\n\n(a) DI\n(b) SIADH\n(c) Addisonian Crisis\n(d) Cerebral salt wasting DISEASE", "role": "user" }, { "content": "(c) Addisonian Crisis", "role": "assistant" } ]
ae3773b2-c801-4738-961c-d4704c74de03
Distribution of blood flow is mainly regulated by the A) Venules B) Arteries C) Capillaries D) Arterioles
Arteries
Arterioles
Capillaries
Venules
1
single
Arterioles regulate the distribution of blood flow by altering their diameter to increase or decrease the peripheral resistance as required.
Physiology
null
D) Arterioles
A) Venules B) Arteries C) Capillaries D) Arterioles
D)
[ "A)", "B)", "C)" ]
[ "A) Venules", "B) Arteries", "C) Capillaries" ]
A) Venules
Choose the correct answer from the options below.
[ { "content": "Distribution of blood flow is mainly regulated by the\n\nA) Venules\nB) Arteries\nC) Capillaries\nD) Arterioles", "role": "user" }, { "content": "D) Arterioles", "role": "assistant" } ]
5afd52af-513a-4600-9dae-8c6bda73826b
Glutamine synthetase is a I. Isomerase II. Lyase III. Transferase IV. Ligase
Isomerase
Ligase
Lyase
Transferase
1
single
Ligases are enzymes that link two substrate together,usually with the simultaneous hydrolysis of ATP. Glutamine synthetase catalyses the amidation of glutamic acid to glutamine.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 49 and 224
Biochemistry
Metabolism of protein and amino acid
IV. Ligase
I. Isomerase II. Lyase III. Transferase IV. Ligase
IV.
[ "I.", "II.", "III." ]
[ "I. Isomerase", "II. Lyase", "III. Transferase" ]
II. Lyase
Choose the correct answer from the options below.
[ { "content": "Glutamine synthetase is a\n\nI. Isomerase\nII. Lyase\nIII. Transferase\nIV. Ligase", "role": "user" }, { "content": "IV. Ligase", "role": "assistant" } ]
f30f742d-a08c-476b-91ba-cd8f341d473c
The operating temperature in an ethylene oxide sterilization during warm cycle is (a) 68-88 degree c (b) 20-35 degree c (c) 92-110 degree c (d) 49-63 degree c
20-35 degree c
49-63 degree c
68-88 degree c
92-110 degree c
1
single
null
Microbiology
null
(d) 49-63 degree c
(a) 68-88 degree c (b) 20-35 degree c (c) 92-110 degree c (d) 49-63 degree c
(d)
[ "(a)", "(b)", "(c)" ]
[ "(a) 68-88 degree c", "(b) 20-35 degree c", "(c) 92-110 degree c" ]
(a) 68-88 degree c
Choose the correct answer from the options below.
[ { "content": "The operating temperature in an ethylene oxide sterilization during warm cycle is\n\n(a) 68-88 degree c\n(b) 20-35 degree c\n(c) 92-110 degree c\n(d) 49-63 degree c", "role": "user" }, { "content": "(d) 49-63 degree c", "role": "assistant" } ]
334866ff-361f-45ed-a875-888c167f1e28
Coris disease is due to defect in a. Hepatic phosphorylase b. Branching enzyme c. Myophosphorylase d. Debranching enzyme
Branching enzyme
Debranching enzyme
Myophosphorylase
Hepatic phosphorylase
1
single
It is type III glycogen storage disease. to deficiency of the debranching enzyme. Clinical features: highly branched dextrin accumulate, fasting hypoglycemia, hepatomegaly.Ref: DM Vasudevan, 7th edition, page no: 125
Biochemistry
Metabolism of carbohydrate
d. Debranching enzyme
a. Hepatic phosphorylase b. Branching enzyme c. Myophosphorylase d. Debranching enzyme
d.
[ "a.", "b.", "c." ]
[ "a. Hepatic phosphorylase", "b. Branching enzyme", "c. Myophosphorylase" ]
c. Myophosphorylase
Choose the correct answer from the options below.
[ { "content": "Coris disease is due to defect in\n\na. Hepatic phosphorylase\nb. Branching enzyme\nc. Myophosphorylase\nd. Debranching enzyme", "role": "user" }, { "content": "d. Debranching enzyme", "role": "assistant" } ]
bfb67460-7508-4a50-9c6e-a3423bbee867
What is the net gain of ATPs when Palmitic acid undergoes complete oxidation? A. 106 ATPs B. 100 ATPs C. 28 ATPs D. 128 ATPs
106 ATPs
100 ATPs
28 ATPs
128 ATPs
0
single
Refer the byte "Beta Oxidation"
Biochemistry
null
A. 106 ATPs
A. 106 ATPs B. 100 ATPs C. 28 ATPs D. 128 ATPs
A.
[ "B.", "C.", "D." ]
[ "B. 100 ATPs", "C. 28 ATPs", "D. 128 ATPs" ]
D. 128 ATPs
Choose the correct answer from the options below.
[ { "content": "What is the net gain of ATPs when Palmitic acid undergoes complete oxidation?\n\nA. 106 ATPs\nB. 100 ATPs\nC. 28 ATPs\nD. 128 ATPs", "role": "user" }, { "content": "A. 106 ATPs", "role": "assistant" } ]
7dddda8d-03bd-473e-99e3-76e49ba99fdb
28 yr old man presented with headache. CT head shows a low attenuation mass in left temporoparietal region which has similar density to CSF and shows no enhancement following contrast administration. Diffusion weighted MRI shows high signal. Which of the following is most probable diagnosis? [a] Epidermoid cyst [b] Multiple sclerosis [c] Arachnoid cyst [d] Migraine
Migraine
Arachnoid cyst
Epidermoid cyst
Multiple sclerosis
2
single
When there is Diffusion Restriction, DW-MRI gives a bright signal and has low apparent Diffusion Coefficient(ADC value). Lesions showing Diffusion Restriction Infarct(Acute Infarct)- IOC Abscess Medulloblastoma & Other Cellularity Tumours Epidermoid Cyst There is free diffusion of water within arachnoid cysts therefore DW-MRI is useful to differentiate b/w arachnoid and epidermoid cyst. Clinical history not suppoive of Migraine. Option D: Multiple sclerosis shows Dawson's fingers.
Radiology
Neuroradiology
[a] Epidermoid cyst
[a] Epidermoid cyst [b] Multiple sclerosis [c] Arachnoid cyst [d] Migraine
[a]
[ "[b]", "[c]", "[d]" ]
[ "[b] Multiple sclerosis", "[c] Arachnoid cyst", "[d] Migraine" ]
[d] Migraine
Choose the correct answer from the options below.
[ { "content": "28 yr old man presented with headache. CT head shows a low attenuation mass in left temporoparietal region which has similar density to CSF and shows no enhancement following contrast administration. Diffusion weighted MRI shows high signal. Which of the following is most probable diagnosis?\n\n[a] Epidermoid cyst\n[b] Multiple sclerosis\n[c] Arachnoid cyst\n[d] Migraine", "role": "user" }, { "content": "[a] Epidermoid cyst", "role": "assistant" } ]
0fc2b368-f84c-42bd-89d0-d3c3c559c2e8
Chronic non- spherocytic hemolytic anemia comes under which class of G6PD deficiency? A) Class I B) Class IV C) Class II D) Class III
Class I
Class II
Class III
Class IV
0
single
Class I - severely G6PD deficient associated with chronic non - spherocytic hemolytic anemia.
Medicine
null
A) Class I
A) Class I B) Class IV C) Class II D) Class III
A)
[ "B)", "C)", "D)" ]
[ "B) Class IV", "C) Class II", "D) Class III" ]
B) Class IV
Choose the correct answer from the options below.
[ { "content": "Chronic non- spherocytic hemolytic anemia comes under which class of G6PD deficiency?\n\nA) Class I\nB) Class IV\nC) Class II\nD) Class III", "role": "user" }, { "content": "A) Class I", "role": "assistant" } ]
f8321123-dae8-4950-a5ac-e93d4e57e14c
Frequency of theta wave - I. 12-16 Hz II. 4-8 Hz III. 2-4 Hz IV. 8-12 Hz
2-4 Hz
4-8 Hz
8-12 Hz
12-16 Hz
1
single
Ans. is 'b' i.e., 4-8 Hz Beta (b) waveAlpha (a) waveTheta waveDelta waveRecorded from/seen ino From parietal & frontal region during specific activation of these parts of braino Seen in drowsiness & children and patients awake, at rest with eyes open.o Recorded from parieto occipital regiono Seen in almost all normal adults when they are awake and in quiet resting state of cerebrationo Seen in awake patient at rest with mind wandering and eyes closed.o Seen in hippocampuso In parietal and temporal region of normal children & drowsiness, emotional stress in adults especially disappointment and frustration.Seen in very deep NR EM sleep & infant, serious organic brain disease, in subcortical transactions separating the ceberal cortex from thalamus.Frequency>14 Hz8-13 Hzo 4-7 Hzo 3-5 Hz (min.)AmplitudeLow amplitudeo High amplitudeo High amplitudeo Large amplitude (Max)Voltage o 50 micro volts (usually) to 100 o 2 to 4 times greater than most other types
Physiology
Sleep Physiology
II. 4-8 Hz
I. 12-16 Hz II. 4-8 Hz III. 2-4 Hz IV. 8-12 Hz
II.
[ "I.", "III.", "IV." ]
[ "I. 12-16 Hz", "III. 2-4 Hz", "IV. 8-12 Hz" ]
III. 2-4 Hz
Choose the correct answer from the options below.
[ { "content": "Frequency of theta wave -\n\nI. 12-16 Hz\nII. 4-8 Hz\nIII. 2-4 Hz\nIV. 8-12 Hz", "role": "user" }, { "content": "II. 4-8 Hz", "role": "assistant" } ]
0bbf3867-4d73-4e1f-a38d-57efd7ecf019
Presynaptic facilitation is caused by i. Prolonged opening of sodium channels ii. Prolonged closure of potassium channels iii. Prolonged opening of chloride channels iv. Prolonged opening of calcium channels
Prolonged opening of calcium channels
Prolonged opening of chloride channels
Prolonged opening of sodium channels
Prolonged closure of potassium channels
0
single
Presynaptic facilitation: when a third neuron facilitates the presynaptic neuron at it ternimal end is called presynaptic facilitation It causes increased neurotransmitters by opening ca+ channals Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:675,676,677
Physiology
General physiology
iv. Prolonged opening of calcium channels
i. Prolonged opening of sodium channels ii. Prolonged closure of potassium channels iii. Prolonged opening of chloride channels iv. Prolonged opening of calcium channels
iv.
[ "i.", "ii.", "iii." ]
[ "i. Prolonged opening of sodium channels", "ii. Prolonged closure of potassium channels", "iii. Prolonged opening of chloride channels" ]
iii. Prolonged opening of chloride channels
Choose the correct answer from the options below.
[ { "content": "Presynaptic facilitation is caused by\n\ni. Prolonged opening of sodium channels\nii. Prolonged closure of potassium channels\niii. Prolonged opening of chloride channels\niv. Prolonged opening of calcium channels", "role": "user" }, { "content": "iv. Prolonged opening of calcium channels", "role": "assistant" } ]
ba3c399d-9f73-4bf0-a0a0-6f7507b7a3e2
Oxygen dissociation curve shifts to right in the following condition: I. Hyperkalemia II. Severe anemia III. Metabolic alkalosis IV. Hypokalemia
Hyperkalemia
Hypokalemia
Metabolic alkalosis
Severe anemia
3
single
Most forms of anemia do not affect the oxyhemoglobin dissociation curve if the association of oxygen and hemoglobin is expressed as percent saturation. It is the amount of hemoglobin that decreases, not the percent saturation or even the aerial PO2. The aerial content of oxygen, however, in milliliters of oxygen per 100 mL of blood, is reduced, because the decreased amount of hemoglobin per 100 mL of blood decreases the oxygen-carrying capacity of the blood. Anemia severe enough to increase tissue anaerobic metabolism causes metabolic acidosis and a rightward shift of the oxyhemoglobin dissociation curve. Ref: Levitzky M.G. (2013). Chapter 7. Transpo of Oxygen and Carbon Dioxide in the Blood. In M.G. Levitzky (Ed), Pulmonary Physiology, 8e.
Physiology
null
II. Severe anemia
I. Hyperkalemia II. Severe anemia III. Metabolic alkalosis IV. Hypokalemia
II.
[ "I.", "III.", "IV." ]
[ "I. Hyperkalemia", "III. Metabolic alkalosis", "IV. Hypokalemia" ]
IV. Hypokalemia
Choose the correct answer from the options below.
[ { "content": "Oxygen dissociation curve shifts to right in the following condition:\n\nI. Hyperkalemia\nII. Severe anemia\nIII. Metabolic alkalosis\nIV. Hypokalemia", "role": "user" }, { "content": "II. Severe anemia", "role": "assistant" } ]
e84da0a4-bd04-4ffb-8058-c007300e2d4a
True statement regarding poal venous system is? (a) Valves are present in the intrahepatic system (b) There are about 10-12 valves along the entire course (c) Whole system is valve less (d) Valves are present at the junction of superior mesenteric aery and splenic aery
Valves are present at the junction of superior mesenteric aery and splenic aery
Whole system is valve less
Valves are present in the intrahepatic system
There are about 10-12 valves along the entire course
1
multi
Whole system is valve less REF: BDC 4th edition vol II p. 268-71, Gray's Anatomy 39th edition p. 1218 In adults, the poal vein and its tributaries have no valves. In fetal life and for a sho postnatal period valves are d emonstrable in its tributaries, but they usually atrophy. Rarely some persist in an atrophic form into adulthood.
Anatomy
null
(c) Whole system is valve less
(a) Valves are present in the intrahepatic system (b) There are about 10-12 valves along the entire course (c) Whole system is valve less (d) Valves are present at the junction of superior mesenteric aery and splenic aery
(c)
[ "(a)", "(b)", "(d)" ]
[ "(a) Valves are present in the intrahepatic system", "(b) There are about 10-12 valves along the entire course", "(d) Valves are present at the junction of superior mesenteric aery and splenic aery" ]
(d) Valves are present at the junction of superior mesenteric aery and splenic aery
Choose the correct answer from the options below.
[ { "content": "True statement regarding poal venous system is?\n\n(a) Valves are present in the intrahepatic system\n(b) There are about 10-12 valves along the entire course\n(c) Whole system is valve less\n(d) Valves are present at the junction of superior mesenteric aery and splenic aery", "role": "user" }, { "content": "(c) Whole system is valve less", "role": "assistant" } ]
2361e501-1a3a-47e1-b792-697af05966c9
Ventricle of Morgagni is situated in: 1. Larynx between true and false cords 2. Nasopharynx representing epithelial diverticulum which forms anterior lobe of pituitary 3. Nose above the vestibule and anterior to middle turbinate 4. Between base of skull and upper border of superior constrictor
Larynx between true and false cords
Between base of skull and upper border of superior constrictor
Nasopharynx representing epithelial diverticulum which forms anterior lobe of pituitary
Nose above the vestibule and anterior to middle turbinate
0
multi
Ventricle of Morgagni, commonly called the ventricle of larynx, is situated between the false and true vocal cords.The defect between base of skull and upper border of superior constrictor which is covered by buccopharyngeal fascia and pierced by eustachian tube is called sinus of Morgagni.The diverticulum of nasopharyngeal mucosa which gives rise to anterior lobe of pituitary is called Rathke's pouch. It may persist as craniopharyngeal canal.
ENT
Larynx
1. Larynx between true and false cords
1. Larynx between true and false cords 2. Nasopharynx representing epithelial diverticulum which forms anterior lobe of pituitary 3. Nose above the vestibule and anterior to middle turbinate 4. Between base of skull and upper border of superior constrictor
1.
[ "2.", "3.", "4." ]
[ "2. Nasopharynx representing epithelial diverticulum which forms anterior lobe of pituitary", "3. Nose above the vestibule and anterior to middle turbinate", "4. Between base of skull and upper border of superior constrictor" ]
4. Between base of skull and upper border of superior constrictor
Choose the correct answer from the options below.
[ { "content": "Ventricle of Morgagni is situated in:\n\n1. Larynx between true and false cords\n2. Nasopharynx representing epithelial diverticulum which forms anterior lobe of pituitary\n3. Nose above the vestibule and anterior to middle turbinate\n4. Between base of skull and upper border of superior constrictor", "role": "user" }, { "content": "1. Larynx between true and false cords", "role": "assistant" } ]
6cb1efbc-131c-420e-b331-94fbff68b864
Mechanism of digitalis in atrial fibrillation: (a) Na+ K+ ATP ase pump inhibition (b) Bradycardia (c) Increase refractoriness of AV node (d) Decrease in contractility
Decrease in contractility
Na+ K+ ATP ase pump inhibition
Increase refractoriness of AV node
Bradycardia
2
single
Ans. C. Increase refractoriness of AV nodeDigoxin is inotropic agent used in heart failure. It has positive inotropic effect and negative chronotropic effect. Inotropic effect is due to blockade of Na+K+ATPase pump. Chronotropic effect is due to vagomimetic effect which increase the refractoriness of AV node. This mechanism is utilized in atrial flutter and fibrillation. Answer is C
Pharmacology
C.V.S
(c) Increase refractoriness of AV node
(a) Na+ K+ ATP ase pump inhibition (b) Bradycardia (c) Increase refractoriness of AV node (d) Decrease in contractility
(c)
[ "(a)", "(b)", "(d)" ]
[ "(a) Na+ K+ ATP ase pump inhibition", "(b) Bradycardia", "(d) Decrease in contractility" ]
(d) Decrease in contractility
Choose the correct answer from the options below.
[ { "content": "Mechanism of digitalis in atrial fibrillation:\n\n(a) Na+ K+ ATP ase pump inhibition\n(b) Bradycardia\n(c) Increase refractoriness of AV node\n(d) Decrease in contractility", "role": "user" }, { "content": "(c) Increase refractoriness of AV node", "role": "assistant" } ]
f7cffb4d-bfd3-4eb6-89bf-8f7c691005c0
Pattern theory of pain control was given by I. Descartes II. Goldschneider III. Melzack IV. Von frey
Von frey
Melzack
Goldschneider
Descartes
2
single
null
Surgery
null
II. Goldschneider
I. Descartes II. Goldschneider III. Melzack IV. Von frey
II.
[ "I.", "III.", "IV." ]
[ "I. Descartes", "III. Melzack", "IV. Von frey" ]
IV. Von frey
Choose the correct answer from the options below.
[ { "content": "Pattern theory of pain control was given by\n\nI. Descartes\nII. Goldschneider\nIII. Melzack\nIV. Von frey", "role": "user" }, { "content": "II. Goldschneider", "role": "assistant" } ]
f2fff366-7a06-4976-85e7-908450c55a97
O2 is given during anaesthesia to prevent – (A) Hypercapnia (B) Pain (C) Hypoxia (D) Hypotension
Pain
Hypoxia
Hypercapnia
Hypotension
1
single
null
Anaesthesia
null
(C) Hypoxia
(A) Hypercapnia (B) Pain (C) Hypoxia (D) Hypotension
(C)
[ "(A)", "(B)", "(D)" ]
[ "(A) Hypercapnia", "(B) Pain", "(D) Hypotension" ]
(B) Pain
Choose the correct answer from the options below.
[ { "content": "O2 is given during anaesthesia to prevent –\n\n(A) Hypercapnia\n(B) Pain\n(C) Hypoxia\n(D) Hypotension", "role": "user" }, { "content": "(C) Hypoxia", "role": "assistant" } ]
5e7cf7b1-d84e-4b6d-9e10-99829c269f27
Zidovudine causes : (A) Ototoxicity (B) Neutropenia (C) Nephrotoxicity (D) Neurotoxicity
Neurotoxicity
Nephrotoxicity
Neutropenia
Ototoxicity
2
single
null
Pharmacology
null
(B) Neutropenia
(A) Ototoxicity (B) Neutropenia (C) Nephrotoxicity (D) Neurotoxicity
(B)
[ "(A)", "(C)", "(D)" ]
[ "(A) Ototoxicity", "(C) Nephrotoxicity", "(D) Neurotoxicity" ]
(A) Ototoxicity
Choose the correct answer from the options below.
[ { "content": "Zidovudine causes :\n\n(A) Ototoxicity\n(B) Neutropenia\n(C) Nephrotoxicity\n(D) Neurotoxicity", "role": "user" }, { "content": "(B) Neutropenia", "role": "assistant" } ]
ada4c094-8189-4e6e-8b96-be5e3486f702
In a highly selective vagotomy, the vagal supply is severed to - i. Pylorus ii. Proximal two-thirds of stomach iii. Antrum iv. Whole of stomach
Antrum
Proximal two-thirds of stomach
Pylorus
Whole of stomach
1
single
null
Surgery
null
ii. Proximal two-thirds of stomach
i. Pylorus ii. Proximal two-thirds of stomach iii. Antrum iv. Whole of stomach
ii.
[ "i.", "iii.", "iv." ]
[ "i. Pylorus", "iii. Antrum", "iv. Whole of stomach" ]
iv. Whole of stomach
Choose the correct answer from the options below.
[ { "content": "In a highly selective vagotomy, the vagal supply is severed to -\n\ni. Pylorus\nii. Proximal two-thirds of stomach\niii. Antrum\niv. Whole of stomach", "role": "user" }, { "content": "ii. Proximal two-thirds of stomach", "role": "assistant" } ]
d93a21c2-4c4f-44cc-ae73-4710f7a45f04
Cyst with scolex and hooks A) Schistosoma B) T solium C) Echinococus D) H. nana
T solium
H. nana
Echinococus
Schistosoma
0
single
(A) T. solium
Microbiology
Misc.
B) T solium
A) Schistosoma B) T solium C) Echinococus D) H. nana
B)
[ "A)", "C)", "D)" ]
[ "A) Schistosoma", "C) Echinococus", "D) H. nana" ]
A) Schistosoma
Choose the correct answer from the options below.
[ { "content": "Cyst with scolex and hooks\n\nA) Schistosoma\nB) T solium\nC) Echinococus\nD) H. nana", "role": "user" }, { "content": "B) T solium", "role": "assistant" } ]
05d57ef0-18b1-4998-975c-34fc3e780fd3
Carbamoyl phosphate synthase I is used in - (1) Purine synthesis (2) Uronic acid pathway (3) Urea cycle (4) Pyrimidine synthesis
Purine synthesis
Pyrimidine synthesis
Urea cycle
Uronic acid pathway
2
single
Ans. is 'c' i.e., Urea cycle o Carbamyl phosphate synthase I - Urea cycleo Carbamyl phosphate synthase II - Pyrimidine synthesisUrea cvcleo Ammonia is ultimately disposed of by formation of urea by "Kreb's Henseleit urea cycle" in the liverr. Urea cycle takes place both in mitochondria and cytosol. First two reactions of urea cycle occur in the mitochondria, and remaining reactions occurs in cytosolr.o Biosynthesis of urea occurs in five steps.Carbamoyl phosphate synthase-I (CPS-I), a mitochondrial enzyme, catalyzes the formation of carbamoyl phosphater by condensation of CO2 and ammonia. Two molecules of ATP are required for the reaction. CPS-I is the rate limiting enzyme of urea cycle0. It is an allosteric enzyme and allosterically activated by N-acetyl glutamater.Ornithine transcarbamoylaser catalyzes the formation of citruliine from carbamoyl phosphate and ornithiner.Arginosuccinate synthase6 catalyzes the formation of arginosuccinate from citruliine and aspartate. This reaction requires 1ATP, but 2 high energy phosphate bonds are consumed as ATP is converted to AMP + PPi. The amino group of aspartate provides one of the two nitrogen atoms that appear in urear (The other one is provided by ammonia NH4 r).Arginosuccinate lyase (arginosuccinase) catalyses the cleavage of arginosuccinate into arginine and fumarate. Fumarate enters in TCA cycle.Arginaser catalyses the formation of urea from argininer by hydrolytic cleavage of arginine to yield urea and ornithine. Ornithine is thus regenerated and can enter mitochondria to initiate another round of the urea cycle.o The source of two nitrogen atoms of urea one from ammoniar and one from amino group of aspartate6. Source of carbon is CO2r. Thus out of all amino acids in%rolved in urea cycle aspartate is consumed, while there is no net loss or gain of ornithine, citruliine, arginosuccinate or arginine. There is production of fumarate as by productr.o 3 molecules of ATP are consumed (2 in first reaction and 1 in third reaction). However, 4 high energy phosphate bonds are utilized as 3rd ATP is converted to AMP+PPi.
Biochemistry
Metabolism of Purines and Pyrimidines
(3) Urea cycle
(1) Purine synthesis (2) Uronic acid pathway (3) Urea cycle (4) Pyrimidine synthesis
(3)
[ "(1)", "(2)", "(4)" ]
[ "(1) Purine synthesis", "(2) Uronic acid pathway", "(4) Pyrimidine synthesis" ]
(1) Purine synthesis
Choose the correct answer from the options below.
[ { "content": "Carbamoyl phosphate synthase I is used in -\n\n(1) Purine synthesis\n(2) Uronic acid pathway\n(3) Urea cycle\n(4) Pyrimidine synthesis", "role": "user" }, { "content": "(3) Urea cycle", "role": "assistant" } ]
33e70f79-a1f8-4d79-8766-6f34147cf44c
Pterygium of nail is seen in [1] Alopecia areata [2] Lichen planus [3] Tinea unguium [4] Psoriasis
Lichen planus
Psoriasis
Tinea unguium
Alopecia areata
0
single
Pterygium of nail Pterygium unguis results from a scarring involving the nail fold extending onto the matrix. "dorsal pterygium" where proximal nail fold fuses to matrix and later to nail bed "ventral pterygium" where a distal extension of the hyponychium attaches to the undersurface of the nail plate thereby obliterating the distal nail groove. Dorsal pterygium is classically seen in lichen planus. It may also be seen in burns, cicatricial pemphigoid, dyskeratosis congenital, graft versus host disease, radiodermatitis, and lupus erythematosus. ventral pterygium is seen in leprosy, neurofibromatosis, subungual exostosis, lupus erythematosus, and systemic sclerosis. IADVL Textbook of dermatology page 1075
Dental
Autoimmune skin disorders
[2] Lichen planus
[1] Alopecia areata [2] Lichen planus [3] Tinea unguium [4] Psoriasis
[2]
[ "[1]", "[3]", "[4]" ]
[ "[1] Alopecia areata", "[3] Tinea unguium", "[4] Psoriasis" ]
[4] Psoriasis
Choose the correct answer from the options below.
[ { "content": "Pterygium of nail is seen in\n\n[1] Alopecia areata\n[2] Lichen planus\n[3] Tinea unguium\n[4] Psoriasis", "role": "user" }, { "content": "[2] Lichen planus", "role": "assistant" } ]
2ed98e39-4dc4-441d-9f38-97d9f518744b
Which is the watershed area between SMA and IMA that commonly undergoes ischemia? (1) Rectosigmoid Jn. (2) Ileocolic Jn. (3) Hepatic flexure (4) Splenic flexure
Hepatic flexure
Splenic flexure
Rectosigmoid Jn.
Ileocolic Jn.
1
single
Anatomic factors predisposing to colonic ischemia include the narrow caliber of the IMA and occasional vascular variations that lack significant collaterals between the SMA and IMA. Predisposing physiologic factors include the low perfusion pressure at the splenic flexure, a watershed area, a decrease in perfusion associated with colonic motility, and sustained mesenteric vasospasm associated with systemic hypotension or other severe physiologic stress produced by sympathetic activity. There are several weak points in the colonic blood supply, known as watershed areas, which result from incomplete anastomoses of the marginal aeries. These watershed areas are more vulnerable to ischemic injury than other pas of the colon. Splenic flexure is the watershed territory between SMA and IMA. Ref: Tyagi S., Cappell M.S. (2012). Chapter 162. Large Bowel Disorders. In G.V. Lawry, S.C. McKean, J. Matloff, J.J. Ross, D.D. Dressler, D.J. Brotman, J.S. Ginsberg (Eds), Principles and Practice of Hospital Medicine. Retrieved March 6, 2013.
Anatomy
null
(4) Splenic flexure
(1) Rectosigmoid Jn. (2) Ileocolic Jn. (3) Hepatic flexure (4) Splenic flexure
(4)
[ "(1)", "(2)", "(3)" ]
[ "(1) Rectosigmoid Jn.", "(2) Ileocolic Jn.", "(3) Hepatic flexure" ]
(3) Hepatic flexure
Choose the correct answer from the options below.
[ { "content": "Which is the watershed area between SMA and IMA that commonly undergoes ischemia?\n\n(1) Rectosigmoid Jn.\n(2) Ileocolic Jn.\n(3) Hepatic flexure\n(4) Splenic flexure", "role": "user" }, { "content": "(4) Splenic flexure", "role": "assistant" } ]
99d6e6b8-a83a-4afe-9e58-afa39aba6422
Symptomatic Neonatal CNS involvement is most commonly seen in which group of congenital intrauterine infections? a) Rubella and Toxoplasmosis b) CMV and Syphillis c) Rubella and HSV d) CMV and Toxoplasmosis
CMV and Toxoplasmosis
Rubella and Toxoplasmosis
Rubella and HSV
CMV and Syphillis
2
single
CNS involvement is a common feature of "TORCH infection". The newborn is asymptomatic at bih. The baby develops symptoms characteristic of the infection in the late neonatal period. Symptomatic CNS manifestations are most common with herpes and rubella infections. Ref: O P Ghai 6th Edition, Page 165; Vope's Neurology of the born 3rd Edition, Page 675
Pediatrics
null
c) Rubella and HSV
a) Rubella and Toxoplasmosis b) CMV and Syphillis c) Rubella and HSV d) CMV and Toxoplasmosis
c)
[ "a)", "b)", "d)" ]
[ "a) Rubella and Toxoplasmosis", "b) CMV and Syphillis", "d) CMV and Toxoplasmosis" ]
d) CMV and Toxoplasmosis
Choose the correct answer from the options below.
[ { "content": "Symptomatic Neonatal CNS involvement is most commonly seen in which group of congenital intrauterine infections?\n\na) Rubella and Toxoplasmosis\nb) CMV and Syphillis\nc) Rubella and HSV\nd) CMV and Toxoplasmosis", "role": "user" }, { "content": "c) Rubella and HSV", "role": "assistant" } ]
a244d307-e501-4aaf-a5c5-452ee4d1b0e6
Hepatorenal syndrome feature are - (1) Normal renal histology (2) Urine sodium < 10 mEq/L (3) Renal function abnormal even after liver become normal (4) Proteinuria < 500 mg/day
Urine sodium < 10 mEq/L
Normal renal histology
Renal function abnormal even after liver become normal
Proteinuria < 500 mg/day
0
single
Urine sodium hepatorenal syndrome Patients with low urine sodium excretion (< 10mEq/L) are at a greater risk of HRS. Urine sodium and creatinine levels are also used to calculate the fractional excretion of sodium, which is helpful in differentiating HRS and prerenal azotemia from intrinsic renal disease Ref Harrison20th edition pg 245
Medicine
Kidney
(2) Urine sodium < 10 mEq/L
(1) Normal renal histology (2) Urine sodium < 10 mEq/L (3) Renal function abnormal even after liver become normal (4) Proteinuria < 500 mg/day
(2)
[ "(1)", "(3)", "(4)" ]
[ "(1) Normal renal histology", "(3) Renal function abnormal even after liver become normal", "(4) Proteinuria < 500 mg/day" ]
(1) Normal renal histology
Choose the correct answer from the options below.
[ { "content": "Hepatorenal syndrome feature are -\n\n(1) Normal renal histology\n(2) Urine sodium < 10 mEq/L\n(3) Renal function abnormal even after liver become normal\n(4) Proteinuria < 500 mg/day", "role": "user" }, { "content": "(2) Urine sodium < 10 mEq/L", "role": "assistant" } ]
cb50cded-1a26-469f-9df2-87be1173706c
Which muscle of larynx is not supplied by recurrent laryngeal nerve - (a) Interarytenoid (b) Thyroarytenoid (c) Vocalis (d) Cricothyroid
Vocalis
Thyroarytenoid
Cricothyroid
Interarytenoid
2
single
Ans. is 'c' i.e., Cricothyroid o All intrinsic muscles are supplied by the reccurrent laryngeal nerve except cricothyroid which is supplied by the external laryngeal nerve.Nerve supply of larynxo The main cranial nerve innervating the larynx is the vagus nerve via its branches; superior laryngeal nerve (SLN) and recurrent laryngeal nerve (RLN).Sensory supply of larynxo Above the level of vocal cords, larynx is supplied by internal laryngeal nerve, a branch of superior laryngeal nerve.o Below the vocal cord, larynx is supplied by recurrent laryngeal nerve.Motor supply of larynxo All the intrinsic muscles of larynx are supplied by recurrent laryngeal nerve except for cricothyroid muscle.o Cricothyroid is supplied by external laryngeal nerve, a branch of superior laryngeal nerve.
ENT
Larynx
(d) Cricothyroid
(a) Interarytenoid (b) Thyroarytenoid (c) Vocalis (d) Cricothyroid
(d)
[ "(a)", "(b)", "(c)" ]
[ "(a) Interarytenoid", "(b) Thyroarytenoid", "(c) Vocalis" ]
(b) Thyroarytenoid
Choose the correct answer from the options below.
[ { "content": "Which muscle of larynx is not supplied by recurrent laryngeal nerve -\n\n(a) Interarytenoid\n(b) Thyroarytenoid\n(c) Vocalis\n(d) Cricothyroid", "role": "user" }, { "content": "(d) Cricothyroid", "role": "assistant" } ]
5c5e80a9-c8d8-432d-8505-e263144c01d2
Flexner-Wintersteiner rosettes in microscopy is seen in: September 2009 (A) Neuroblastoma (B) Retinitis pigmentosa (C) Retinoblastoma (D) Trauma
Retinitis pigmentosa
Trauma
Retinoblastoma
Neuroblastoma
2
single
Ans. C: Retinoblastoma Leukocoria (white pupillary reflex or cat's eye reflex) is the most common presenting sign of retinoblastoma, accounting for about 56.1% of cases. Strabismus, which occurs as a result of visual loss, is the second most common mode of presentation. Thus, funduscopic examination through a well-dilated pupil must be performed in all cases of childhood strabismus. Retinoblastoma can cause secondary changes in the eye, including glaucoma, retinal detachment, and inflammation secondary to tumor necrosis. Pseudouveitis, with a red eye and pain and associated hypopyon and hyphema, is a rare presentation. It is characteristic of an infiltrating type of retinoblastoma in which the tumor cells invade the retina diffusely without forming a discrete tumor mass. Orbital inflammation mimicking orbital cellulitis may occur in eyes with necrotic tumors and does not necessarily imply extraocular extension. Proptosis is a more common presenting symptom in most underdeveloped countries. Histologically, the growth consists chiefly of small round cells with large nuclei resembling the cells of the nuclear layers of the retina. Many of these cells stain poorly, showing that they are undergoing necrosis. Flexner-Wintersteiner rosettes like formation of cells resembling the rods and cones may be found.
Ophthalmology
null
(C) Retinoblastoma
(A) Neuroblastoma (B) Retinitis pigmentosa (C) Retinoblastoma (D) Trauma
(C)
[ "(A)", "(B)", "(D)" ]
[ "(A) Neuroblastoma", "(B) Retinitis pigmentosa", "(D) Trauma" ]
(B) Retinitis pigmentosa
Choose the correct answer from the options below.
[ { "content": "Flexner-Wintersteiner rosettes in microscopy is seen in: September 2009\n\n(A) Neuroblastoma\n(B) Retinitis pigmentosa\n(C) Retinoblastoma\n(D) Trauma", "role": "user" }, { "content": "(C) Retinoblastoma", "role": "assistant" } ]
2c2141a4-50a0-4d3e-b995-b142d5decd23
Spontaneous rupture of the liver occurs in ? I. Spherocytosis II. Poal hypeension III. Hepatoma IV. Secondary deposits
Hepatoma
Poal hypeension
Spherocytosis
Secondary deposits
0
single
Ans. is 'a' i.e., Hepatoma Spontaneous rupture of the liver can be seen in both beningn and malignant tumors of the liver. Hepatoma or HCC is the most common cause.
Surgery
null
III. Hepatoma
I. Spherocytosis II. Poal hypeension III. Hepatoma IV. Secondary deposits
III.
[ "I.", "II.", "IV." ]
[ "I. Spherocytosis", "II. Poal hypeension", "IV. Secondary deposits" ]
II. Poal hypeension
Choose the correct answer from the options below.
[ { "content": "Spontaneous rupture of the liver occurs in ?\n\nI. Spherocytosis\nII. Poal hypeension\nIII. Hepatoma\nIV. Secondary deposits", "role": "user" }, { "content": "III. Hepatoma", "role": "assistant" } ]
d8b6713d-0345-4407-a979-13fe99249479
Cervical cerclage is offered to pregnant women with prior history of preterm bih if cervical length is less than A. 40mm B. 30mm C. 35mm D. 25mm
25mm
30mm
35mm
40mm
0
single
Cervical length screening is now recommended for women with prior history of preterm bih. Between 16 and 24weeks gestation sonographic cervical measurement is completed every 2weeks. If initial or subsequent cervical length is 25 to 29mm, then a weekly interval is considered. If the cervical measurement is <25mm, cerclage is offered. Women without a history of preterm bih but with a sho cervix incidentally identified sonographically, progesterone therapy is to be offered instead of cerclage(Ref: William's Obstetrics; 25th edition)
Gynaecology & Obstetrics
All India exam
D. 25mm
A. 40mm B. 30mm C. 35mm D. 25mm
D.
[ "A.", "B.", "C." ]
[ "A. 40mm", "B. 30mm", "C. 35mm" ]
A. 40mm
Choose the correct answer from the options below.
[ { "content": "Cervical cerclage is offered to pregnant women with prior history of preterm bih if cervical length is less than\n\nA. 40mm\nB. 30mm\nC. 35mm\nD. 25mm", "role": "user" }, { "content": "D. 25mm", "role": "assistant" } ]
9de00ad5-ce32-4eff-a4d0-43b3e360cec2
The following drug is indicated in the treatment of pityriasis versicolar : [a] Metronidazole [b] Ketoconazole [c] Griseofulvin [d] Chloroquine
Ketoconazole
Metronidazole
Griseofulvin
Chloroquine
0
single
A i.e. Ketoconazole - Pityriasis versicolor is superficial mycosis caused by mycelial phase of yeast Malassezia (furfur, globosa, sympodialis)Q. It presents with multiple, small, hypopigmented (usually or pink-salmon or hyperpigmented) scaly macules that develop insidiously over the trunk, chest, back and shoulders in young adultsQ. Macules sta around the hair follicle and then merge with each other to form large areasQ. The characteristic scale is futfuraceous or dust like (fine, branny scaling)Q. Microscopic examination (in 10% KOH) show bananas and grapes (or spaghetti and meat balls) appearance and Wood's lamp examination show apple (yellow) green fluoresce. - Griseofulvin is used systemically for dermatophytosis (tinea infections) but it is ineffective topicallyQ and has no role in treatment of tinea versicolor and candidaQ.
Skin
null
[b] Ketoconazole
[a] Metronidazole [b] Ketoconazole [c] Griseofulvin [d] Chloroquine
[b]
[ "[a]", "[c]", "[d]" ]
[ "[a] Metronidazole", "[c] Griseofulvin", "[d] Chloroquine" ]
[c] Griseofulvin
Choose the correct answer from the options below.
[ { "content": "The following drug is indicated in the treatment of pityriasis versicolar :\n\n[a] Metronidazole\n[b] Ketoconazole\n[c] Griseofulvin\n[d] Chloroquine", "role": "user" }, { "content": "[b] Ketoconazole", "role": "assistant" } ]
7a6d301e-7ff1-49ad-b34e-7200ccdbeca1
True statement regarding use of adrenaline in anaphylactic shock is? (1) 1:10,000 concentration is commonly used (2) 0.5 mg dose is administered by s.c.route (3) Same concentration can be given for s.c.as well as i.v.route (4) It is repeated after every 4-6 hours
0.5 mg dose is administered by s.c.route
1:10,000 concentration is commonly used
It is repeated after every 4-6 hours
Same concentration can be given for s.c.as well as i.v.route
0
multi
Ans. is 'a' i.e., 0.5 mg dose is administered by s.c.route Adrenaline 0.5 ml of 1:1000 solution (i.e., 0.5 mg) by s.c. or i.m. route is the DOC for anaphylactic shock. If not responding, it can be repeated after 5 minutes. In desperate circumstances i.v. route can be used but it must be diluted 10 times (i.e., 1:10000 concentration).
Pharmacology
null
(2) 0.5 mg dose is administered by s.c.route
(1) 1:10,000 concentration is commonly used (2) 0.5 mg dose is administered by s.c.route (3) Same concentration can be given for s.c.as well as i.v.route (4) It is repeated after every 4-6 hours
(2)
[ "(1)", "(3)", "(4)" ]
[ "(1) 1:10,000 concentration is commonly used", "(3) Same concentration can be given for s.c.as well as i.v.route", "(4) It is repeated after every 4-6 hours" ]
(3) Same concentration can be given for s.c.as well as i.v.route
Choose the correct answer from the options below.
[ { "content": "True statement regarding use of adrenaline in anaphylactic shock is?\n\n(1) 1:10,000 concentration is commonly used\n(2) 0.5 mg dose is administered by s.c.route\n(3) Same concentration can be given for s.c.as well as i.v.route\n(4) It is repeated after every 4-6 hours", "role": "user" }, { "content": "(2) 0.5 mg dose is administered by s.c.route", "role": "assistant" } ]
3a65e4dc-8dcb-4bdb-b3ef-84a7af90ec94
Which of the following are signs of tentorial herniation? 1) Sixth nerve palsy 2) All of the above 3) Sunset sign 4) Decerebrate rigidity
Sunset sign
Sixth nerve palsy
Decerebrate rigidity
All of the above
3
multi
Ans. D. All of the aboveIf the intracranial pressure exceeds the compensatory mechanisms, herniation with secondary compression and infarction of brain tissue occurs. Common signs of tentorial herniation include sunset sign, sixth nerve palsy, coma, tonic fits, decebrate rigidity, hypertension, bradycardia, hemiplegia, hemianopia and bilateral fixed dilated pupils.
Pediatrics
Central Nervous System
2) All of the above
1) Sixth nerve palsy 2) All of the above 3) Sunset sign 4) Decerebrate rigidity
2)
[ "1)", "3)", "4)" ]
[ "1) Sixth nerve palsy", "3) Sunset sign", "4) Decerebrate rigidity" ]
3) Sunset sign
Choose the correct answer from the options below.
[ { "content": "Which of the following are signs of tentorial herniation?\n\n1) Sixth nerve palsy\n2) All of the above\n3) Sunset sign\n4) Decerebrate rigidity", "role": "user" }, { "content": "2) All of the above", "role": "assistant" } ]
ee7543bb-224c-4dbb-b33d-4ed2bc53110e
All of the following are true except: A. Myeloperoxidase action is mainly due to OCI- B. Chediak-Higashi syndrome is due to defective phagolysosome formation C. NADPH oxidase acts via superoxide ions D. In Brutons agammaglobulinemia opsonisation is not affected
NADPH oxidase acts via superoxide ions
Chediak-Higashi syndrome is due to defective phagolysosome formation
In Brutons agammaglobulinemia opsonisation is not affected
Myeloperoxidase action is mainly due to OCI-
2
multi
c. In Brutons agammaglobulinemia opsonization is not affected(Ref: Nelson's 20/e p 1012-1016, Ghai8/ep 186)IgM is important for opsonization, so in Brutons agammaglobulinemia opsonisation is affected.
Pediatrics
New Born Infants
D. In Brutons agammaglobulinemia opsonisation is not affected
A. Myeloperoxidase action is mainly due to OCI- B. Chediak-Higashi syndrome is due to defective phagolysosome formation C. NADPH oxidase acts via superoxide ions D. In Brutons agammaglobulinemia opsonisation is not affected
D.
[ "A.", "B.", "C." ]
[ "A. Myeloperoxidase action is mainly due to OCI-", "B. Chediak-Higashi syndrome is due to defective phagolysosome formation", "C. NADPH oxidase acts via superoxide ions" ]
B. Chediak-Higashi syndrome is due to defective phagolysosome formation
Choose the correct answer from the options below.
[ { "content": "All of the following are true except:\n\nA. Myeloperoxidase action is mainly due to OCI-\nB. Chediak-Higashi syndrome is due to defective phagolysosome formation\nC. NADPH oxidase acts via superoxide ions\nD. In Brutons agammaglobulinemia opsonisation is not affected", "role": "user" }, { "content": "D. In Brutons agammaglobulinemia opsonisation is not affected", "role": "assistant" } ]
694d5229-d260-41b3-a4e1-232608661025
Dawn phenomenon refers to- [a] Hypoglycemia followed by hyperglycemia [b] Early morning hyperglycemia [c] Early morning hypolgycemia [d] High insulin levels
Early morning hyperglycemia
Early morning hypolgycemia
Hypoglycemia followed by hyperglycemia
High insulin levels
0
single
Question repeated The dawn phenomenon, sometimes called the dawn effect, is an early-morning (usually between 2 a.m. and 8 a.m.) increase in blood sugar (glucose) relevant to people with diabetes. It is different from chronic Somogyi rebound in that dawn phenomenon is not associated with nocturnal hypoglycemia. The dawn phenomenon can be managed in many patients by avoiding carbohydrate intake at bedtime, adjusting the dosage of medication or insulin, switching to a different medication, or by using an insulin pump to administer extra insulin during early-morning hours. In most of the cases, there is no need to change insulin dosing of patients who encounter the dawn phenomenon.
Medicine
Endocrinology
[b] Early morning hyperglycemia
[a] Hypoglycemia followed by hyperglycemia [b] Early morning hyperglycemia [c] Early morning hypolgycemia [d] High insulin levels
[b]
[ "[a]", "[c]", "[d]" ]
[ "[a] Hypoglycemia followed by hyperglycemia", "[c] Early morning hypolgycemia", "[d] High insulin levels" ]
[d] High insulin levels
Choose the correct answer from the options below.
[ { "content": "Dawn phenomenon refers to-\n\n[a] Hypoglycemia followed by hyperglycemia\n[b] Early morning hyperglycemia\n[c] Early morning hypolgycemia\n[d] High insulin levels", "role": "user" }, { "content": "[b] Early morning hyperglycemia", "role": "assistant" } ]
52cd7973-72df-4573-8f3f-ccaeb6cd8748
All are true regarding dystocia except: [1] It is the M/C indication for primary cesarean delivery [2] ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia [3] Dystocia is difficult labor [4] Dystocia can be due to abnormality in power, passage and passenger
Dystocia is difficult labor
It is the M/C indication for primary cesarean delivery
ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia
Dystocia can be due to abnormality in power, passage and passenger
2
multi
Dystocia literally means difficult labor and is characterized by abnormally slow labor progress. It arises from four distinct abnormalities that may exist singly or in combination: – Abnormalities of the expulsive forces. Uterine contractions maybe insufficiently strong or inappropriately coordinated to efface and dilate the cervix–uterine dysfunction. Also, there may be inadequate voluntary maternal muscle effort during second-stage labor. – Abnormalities of presentation, position, or development of the fetus. – Abnormalities of the maternal bony pelvis–that is, pelvic contraction. – Abnormalities of soft tissues of the reproductive tract that form an obstacle to fetal descent. Common clinical findings in women with ineffective labor Inadequate cervical dilation or fetal descent: Protracted labor–slow progress Arrested labor–no progress Inadequate expulsive effort–ineffective pushing. Fetopelvic disproportion: Excessive fetal size Inadequate pelvic capacity Malpresentation or position of the fetus Ruptured membranes without labor. Dystocia is the most common current indication for primary cesarean delivery. American College of Obstetricians and Gynaecology recommend (1995a) that the cervix be dilated to 4 cm or more before dystocia is diagnosed, thus, the diagnosis often is made before active labor, and therefore before an adequate trial of labor which leads to unnecessary cesarean section.
Gynaecology & Obstetrics
null
[2] ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia
[1] It is the M/C indication for primary cesarean delivery [2] ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia [3] Dystocia is difficult labor [4] Dystocia can be due to abnormality in power, passage and passenger
[2]
[ "[1]", "[3]", "[4]" ]
[ "[1] It is the M/C indication for primary cesarean delivery", "[3] Dystocia is difficult labor", "[4] Dystocia can be due to abnormality in power, passage and passenger" ]
[1] It is the M/C indication for primary cesarean delivery
Choose the correct answer from the options below.
[ { "content": "All are true regarding dystocia except:\n\n[1] It is the M/C indication for primary cesarean delivery\n[2] ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia\n[3] Dystocia is difficult labor\n[4] Dystocia can be due to abnormality in power, passage and passenger", "role": "user" }, { "content": "[2] ACOG recommends the cervix should be atleast 2 cms dilated for diagnosis of dystocia", "role": "assistant" } ]
c5a8eb5f-df62-4e45-b908-7867063e8513
Which of the following type of GIC is used as a base? [A] Type III [B] Type IIa [C] Type I [D] Type IIb
Type I
Type IIa
Type IIb
Type III
3
single
Type I: Luting crowns, bridges and orthodontic brackets. Type IIa: Esthetic restorative cements. Type IIb: Reinforced restorative cements. Type III: Lining cements, base. Ref: Phillip’s Science of Dental Materials ed 12 pg 320
Dental
null
[A] Type III
[A] Type III [B] Type IIa [C] Type I [D] Type IIb
[A]
[ "[B]", "[C]", "[D]" ]
[ "[B] Type IIa", "[C] Type I", "[D] Type IIb" ]
[B] Type IIa
Choose the correct answer from the options below.
[ { "content": "Which of the following type of GIC is used as a base?\n\n[A] Type III\n[B] Type IIa\n[C] Type I\n[D] Type IIb", "role": "user" }, { "content": "[A] Type III", "role": "assistant" } ]
060d3e68-ab85-44b5-a04d-f095e017a63c
Which of the following is a broad spectrum antibiotic ? I. Erythromycin II. Streptomycin III. All IV. Tetracycline
Erythromycin
Streptomycin
Tetracycline
All
2
multi
null
Pharmacology
null
IV. Tetracycline
I. Erythromycin II. Streptomycin III. All IV. Tetracycline
IV.
[ "I.", "II.", "III." ]
[ "I. Erythromycin", "II. Streptomycin", "III. All" ]
I. Erythromycin
Choose the correct answer from the options below.
[ { "content": "Which of the following is a broad spectrum antibiotic ?\n\nI. Erythromycin\nII. Streptomycin\nIII. All\nIV. Tetracycline", "role": "user" }, { "content": "IV. Tetracycline", "role": "assistant" } ]
4f243bb0-bdf6-40f9-a46f-96e389ecea11
A neonate has recurrent attacks of abdominal pain, restless irritability and diaphoresis on feeding. Cardiac auscultation reveals a nonspecific murmur. He is believed to be at risk for M.I. Likely diagnosis here is: (1) VSD (2) ASD (3) TOF (4) Anomalous coronary aery
ASD
VSD
TOF
Anomalous coronary aery
3
single
Normally coronary aery arise from the aoic root, but in this condition it arise from the pulmonary aery. In this case oxygen supply to myocardium is compromised due to delivery of deoxygenated blood and low perfusion pressures. Soon after bih (Neonate) as the pulmonary aerial pressure falls, perfusion pressure to the left coronary aery becomes inadequate. Myocardial infarction and fibrosis may result. Ref: Kliegman, Behrman, Jenson, Stanton (2008), Chapter 432.2, "Anomalous Origin of the Coronary Aeries", In the book, "NELSON TEXTBOOK OF PEDIATRICS", Volume 2, 18th Edition, New Delhi, Pages 1930-31
Pediatrics
null
(4) Anomalous coronary aery
(1) VSD (2) ASD (3) TOF (4) Anomalous coronary aery
(4)
[ "(1)", "(2)", "(3)" ]
[ "(1) VSD", "(2) ASD", "(3) TOF" ]
(1) VSD
Choose the correct answer from the options below.
[ { "content": "A neonate has recurrent attacks of abdominal pain, restless irritability and diaphoresis on feeding. Cardiac auscultation reveals a nonspecific murmur. He is believed to be at risk for M.I. Likely diagnosis here is:\n\n(1) VSD\n(2) ASD\n(3) TOF\n(4) Anomalous coronary aery", "role": "user" }, { "content": "(4) Anomalous coronary aery", "role": "assistant" } ]
e350621b-5922-4955-a17f-eb626b38f668
Green extra aicular ahrodesis done for - a) Coxa vara b) Congenital veical talus c) Genu Valgum d) Cubitus varus
Genu Valgum
Coxa vara
Congenital veical talus
Cubitus varus
2
single
Ans. is 'c' i.e., Congenital Veical Talus Grice and Green procedure is an extra aicular fusion (ahrodesis) of the subtalar joint. It is used in the treatment of patients of congenital veical talus between age of 4 to 8 years old along with open reduction of the deformity.
Surgery
null
b) Congenital veical talus
a) Coxa vara b) Congenital veical talus c) Genu Valgum d) Cubitus varus
b)
[ "a)", "c)", "d)" ]
[ "a) Coxa vara", "c) Genu Valgum", "d) Cubitus varus" ]
d) Cubitus varus
Choose the correct answer from the options below.
[ { "content": "Green extra aicular ahrodesis done for -\n\na) Coxa vara\nb) Congenital veical talus\nc) Genu Valgum\nd) Cubitus varus", "role": "user" }, { "content": "b) Congenital veical talus", "role": "assistant" } ]
96bf26ac-a991-48b0-be79-85b7ea394ea6
Anti cancer drug causing nephrotoxicity - a. Busulfan b. Cyclophosphamide c. Procarbazine d. Cisplatin
Cyclophosphamide
Busulfan
Cisplatin
Procarbazine
2
single
Ans. is 'c' i.e., Cisplatin Platinum compoundo These are alkylating agents and act by similar mechanism,o Drugs are -First generation-CisplatinSecond generation-CarboplatinThird generation-OxaliplatinSide effects of Cisplatino Vomitingo Ototoxicityo Hyperuricemiao Nephrotoxicityo Neuropathy Note-o Cisplatin is most nephrotoxic where as carboplatin is more hematotoxic (bone marrow suppression),o Carboplatin has less nephrotoxic, neurotoxic and ototoxic effects,o Dose limiting toxicity of oxaliplatin is neurotoxicity (Peripheral neuropathy).
Pharmacology
Anti-Neoplastic Agents
d. Cisplatin
a. Busulfan b. Cyclophosphamide c. Procarbazine d. Cisplatin
d.
[ "a.", "b.", "c." ]
[ "a. Busulfan", "b. Cyclophosphamide", "c. Procarbazine" ]
b. Cyclophosphamide
Choose the correct answer from the options below.
[ { "content": "Anti cancer drug causing nephrotoxicity -\n\na. Busulfan\nb. Cyclophosphamide\nc. Procarbazine\nd. Cisplatin", "role": "user" }, { "content": "d. Cisplatin", "role": "assistant" } ]
e6f6ae38-ae91-4a9f-8687-81d7196420b9
K+ sparing diuretic is : a. Furosemide b. Spironolactone c. Thiazide d. None
Furosemide
Spironolactone
Thiazide
None
1
multi
null
Pharmacology
null
b. Spironolactone
a. Furosemide b. Spironolactone c. Thiazide d. None
b.
[ "a.", "c.", "d." ]
[ "a. Furosemide", "c. Thiazide", "d. None" ]
d. None
Choose the correct answer from the options below.
[ { "content": "K+ sparing diuretic is :\n\na. Furosemide\nb. Spironolactone\nc. Thiazide\nd. None", "role": "user" }, { "content": "b. Spironolactone", "role": "assistant" } ]
fdb4243f-830c-4c57-8e98-af143aca8a01
Endemic cretinism is seen when iodine uptake is less than 1. 50microgram/day 2. 5microgram/day 3. 20microgram/day 4. 75microgram/day
5microgram/day
20microgram/day
50microgram/day
75microgram/day
1
single
Endemic cretinism is seen when iodine uptake is less than 20microgram/dayEndemic cretinism is the extreme clinical manifestation of severe hypothyroidism during foetal, neonatal and childhood stages of development. It is characterised by severe and irreversible mental retardation, sho stature, deaf-mutism, spastic dysplegia and squints.Cretinism seen in severe endemic areas is predominantly of two types (a) neurological cretinism, where the neurological manifestations of thyroxin deficiency early in life, i.e. hypothyroidism, were confined to the in-utero or neonatal stages. (b) Myxedematous cretinism, where besides having mental retardation, sufferers also have myxoedema and dwarfism.Associated with goitre when iodine uptake is less than 50microgram/day. Normal requirement is 150microgram/day
Social & Preventive Medicine
Nutrition and health
3. 20microgram/day
1. 50microgram/day 2. 5microgram/day 3. 20microgram/day 4. 75microgram/day
3.
[ "1.", "2.", "4." ]
[ "1. 50microgram/day", "2. 5microgram/day", "4. 75microgram/day" ]
4. 75microgram/day
Choose the correct answer from the options below.
[ { "content": "Endemic cretinism is seen when iodine uptake is less than\n\n1. 50microgram/day\n2. 5microgram/day\n3. 20microgram/day\n4. 75microgram/day", "role": "user" }, { "content": "3. 20microgram/day", "role": "assistant" } ]
5faa05f6-8734-4439-aea9-7dc6d3a5318c
An investigator into the life expectancy of IV drug abusers divides a sample of patients into HIV-positive and HIV-negative groups. What type of data does this division constitute? a. Ordinal b. Interval c. Ration d. Nominal
Nominal
Ordinal
Interval
Ration
0
single
Nominal data (also known as nominal scale) is a type of data that is used to label variables without providing any quantitative value. Given question is about HIV-positive and HIV-negative groups; since there is no order of characteristic and it cannot be measured directly. So,it can't be an ordinal data or metric data respectively. It is nominal data as its division is based only on names, i.e. HIV-positive and HIV-negative groups.
Social & Preventive Medicine
Variables, Scales
d. Nominal
a. Ordinal b. Interval c. Ration d. Nominal
d.
[ "a.", "b.", "c." ]
[ "a. Ordinal", "b. Interval", "c. Ration" ]
a. Ordinal
Choose the correct answer from the options below.
[ { "content": "An investigator into the life expectancy of IV drug abusers divides a sample of patients into HIV-positive and HIV-negative groups. What type of data does this division constitute?\n\na. Ordinal\nb. Interval\nc. Ration\nd. Nominal", "role": "user" }, { "content": "d. Nominal", "role": "assistant" } ]
085e033e-d9c0-4729-bf92-3ae2476ceb22
What is the drug of choice for Obsessive Compulsive Disorder? a) Benzodiazepines b) Fluoxetine c) Alprazolam d) Imipramine
Imipramine
Fluoxetine
Benzodiazepines
Alprazolam
1
single
Ans. (B) Fluoxetine(Ref: Harrison 17/e p2715; CMDT 2010/943; KDT 8/e p492)SSRIs are drug of choice for most of the neurotic disorders including OCD.
Pharmacology
C.N.S
b) Fluoxetine
a) Benzodiazepines b) Fluoxetine c) Alprazolam d) Imipramine
b)
[ "a)", "c)", "d)" ]
[ "a) Benzodiazepines", "c) Alprazolam", "d) Imipramine" ]
a) Benzodiazepines
Choose the correct answer from the options below.
[ { "content": "What is the drug of choice for Obsessive Compulsive Disorder?\n\na) Benzodiazepines\nb) Fluoxetine\nc) Alprazolam\nd) Imipramine", "role": "user" }, { "content": "b) Fluoxetine", "role": "assistant" } ]
19d439fa-59b0-420e-b75f-d16db6cfd7fd
Which true about MDC A. Half the prevalence of HIV-AIDS by 2015 B. Reduce maternal moality by 50% by 1990-2012 C. Reduce hunger and povey by half D. Reduce by 2/3rd the under five moality by year 1990-2012
Reduce by 2/3rd the under five moality by year 1990-2012
Half the prevalence of HIV-AIDS by 2015
Reduce maternal moality by 50% by 1990-2012
Reduce hunger and povey by half
0
multi
Ans. a. Reduce by 2/3rd the under five moality by year 1990-2012 Millennium Development Goals Millennium Development Goal 1: eradicate extreme povey and hungerdeg Target 1.C. Halve, between 1990 and 2015, the propoion of people who suffer from hungerdeg Millennium Development Goal 4: reduce child moalitydeg Target 4.A. Reduce by two-thirds, between 1990 and 2015, the under-five moality ratedeg Millennium Development Goal 5: improve maternal healthdeg - Target 5.A. Reduce by three quaers, between 1990 and 2015, the maternal moality ratiodeg Target 5.B. Achieve, by 2015, universal access to reproductive healthdeg Millennium Development Goal 6: combat HIV/AIDS, malaria and other diseasesdeg Target 6A. Have halted by 2015 and begun to reverse the spread of HIV/AIDSdeg Target 6B. Achieve, by 2010, universal access to treatment for HIV/AIDS for all those who need itQ . Target 6C. Have halted by 2015 and begun to reverse the incidence of malaria and other major diseasesdeg Millennium Development Goal 7: ensure environmental sustainabilitydeg Target 7C: By 2015, halve the propoion of people without sustainable access to safe drinking water and basic sanitationdeg Millennium Development Goal 8: develop a global panership for developmentdeg Target 8E. In cooperation with pharmaceutical companies, provide access to affordable essential medicines in developing countriesdeg
Social & Preventive Medicine
null
D. Reduce by 2/3rd the under five moality by year 1990-2012
A. Half the prevalence of HIV-AIDS by 2015 B. Reduce maternal moality by 50% by 1990-2012 C. Reduce hunger and povey by half D. Reduce by 2/3rd the under five moality by year 1990-2012
D.
[ "A.", "B.", "C." ]
[ "A. Half the prevalence of HIV-AIDS by 2015", "B. Reduce maternal moality by 50% by 1990-2012", "C. Reduce hunger and povey by half" ]
A. Half the prevalence of HIV-AIDS by 2015
Choose the correct answer from the options below.
[ { "content": "Which true about MDC\n\nA. Half the prevalence of HIV-AIDS by 2015\nB. Reduce maternal moality by 50% by 1990-2012\nC. Reduce hunger and povey by half\nD. Reduce by 2/3rd the under five moality by year 1990-2012", "role": "user" }, { "content": "D. Reduce by 2/3rd the under five moality by year 1990-2012", "role": "assistant" } ]
d0259a36-d4f5-42a2-85a0-0a869a2b3b96
On medical check up of a Punjabi student following findings were seen Hb of 9.9gm/d1, RBC count of 5.1 million, MCV of 62.5 fl and RDW of 13.51%. What is the most probable diagnosis ? a) HbD b) Anemia of chronic disease c) Thalassemia trait d) Iron deficiency anemia
HbD
Thalassemia trait
Iron deficiency anemia
Anemia of chronic disease
1
single
Answer- B. Thalassemia traitNormal RDW with low MCV is seen in-- Anemia of chronic diseaseHeterozygous thalassemia (Thalassemia trait)Hemoglobin E trait.
Medicine
null
c) Thalassemia trait
a) HbD b) Anemia of chronic disease c) Thalassemia trait d) Iron deficiency anemia
c)
[ "a)", "b)", "d)" ]
[ "a) HbD", "b) Anemia of chronic disease", "d) Iron deficiency anemia" ]
a) HbD
Choose the correct answer from the options below.
[ { "content": "On medical check up of a Punjabi student following findings were seen Hb of 9.9gm/d1, RBC count of 5.1 million, MCV of 62.5 fl and RDW of 13.51%. What is the most probable diagnosis ?\n\na) HbD\nb) Anemia of chronic disease\nc) Thalassemia trait\nd) Iron deficiency anemia", "role": "user" }, { "content": "c) Thalassemia trait", "role": "assistant" } ]
0c365c0d-492e-41db-acbf-e1ac8a2954a0
In congenital hyperophic pyloric stenosis, the defect is in (1) Circular muscle fibres (2) Longitudinal muscle fibres (3) Mucosa (4) Nerve fibres
Nerve fibres
Circular muscle fibres
Longitudinal muscle fibres
Mucosa
1
single
Infantile Hyperophic Pyloric stenosis In HPS, hyperophy of circular muscle of pylorus results in constriction & obstruction of gastric outlet Accquired condition Incidence of 1 in 3000 to 4000 live bihs This condition is most common between the ages of 3-6 weeks Associated anomalies in 6-20% cases : Esophageal atresia, Hirschprung's disease, ARM and malrotation Ref: Sabiston 20th edition Pgno : 1869
Surgery
G.I.T
(1) Circular muscle fibres
(1) Circular muscle fibres (2) Longitudinal muscle fibres (3) Mucosa (4) Nerve fibres
(1)
[ "(2)", "(3)", "(4)" ]
[ "(2) Longitudinal muscle fibres", "(3) Mucosa", "(4) Nerve fibres" ]
(2) Longitudinal muscle fibres
Choose the correct answer from the options below.
[ { "content": "In congenital hyperophic pyloric stenosis, the defect is in\n\n(1) Circular muscle fibres\n(2) Longitudinal muscle fibres\n(3) Mucosa\n(4) Nerve fibres", "role": "user" }, { "content": "(1) Circular muscle fibres", "role": "assistant" } ]
7e2b88cf-27ae-4920-bf11-7b046622274e
The tubuloglomerular feedback is me­diated by: I. Sensing NaCl concentration in the macula densa II. Sensing of Na+ concentration in the macula densa III. Sensing of HCO3 - concentration in macula densa IV. Opening up of voltage gated Na+ channels in afferent arteriole
Sensing of Na+ concentration in the macula densa
Sensing of HCO3 - concentration in macula densa
Sensing NaCl concentration in the macula densa
Opening up of voltage gated Na+ channels in afferent arteriole
2
single
Macula densa sense both Na+ and Cl- , but Cl- is more important.
Physiology
null
I. Sensing NaCl concentration in the macula densa
I. Sensing NaCl concentration in the macula densa II. Sensing of Na+ concentration in the macula densa III. Sensing of HCO3 - concentration in macula densa IV. Opening up of voltage gated Na+ channels in afferent arteriole
I.
[ "II.", "III.", "IV." ]
[ "II. Sensing of Na+ concentration in the macula densa", "III. Sensing of HCO3 - concentration in macula densa", "IV. Opening up of voltage gated Na+ channels in afferent arteriole" ]
II. Sensing of Na+ concentration in the macula densa
Choose the correct answer from the options below.
[ { "content": "The tubuloglomerular feedback is me­diated by:\n\nI. Sensing NaCl concentration in the macula densa\nII. Sensing of Na+ concentration in the macula densa\nIII. Sensing of HCO3 - concentration in macula densa\nIV. Opening up of voltage gated Na+ channels in afferent arteriole", "role": "user" }, { "content": "I. Sensing NaCl concentration in the macula densa", "role": "assistant" } ]
5a0be6c8-1084-4cc3-9f5b-c1828c537c3a
Which of these fatty acids is found exclusively in breast milk? [a] Docosahexaenoic acid [b] Palmitic [c] Linoleate [d] Linolenic
Linoleate
Linolenic
Palmitic
Docosahexaenoic acid
3
single
Ans. D. Docosahexaenoic acid(Ref: Harper31/e page 197, Table 21.2)Docosahexaenoic acid is present in fish oils, phospholipids of brain, algal oils.DHA is otherwise called cervonic acid.It belongs to o3 fatty acid.
Biochemistry
Lipids
[a] Docosahexaenoic acid
[a] Docosahexaenoic acid [b] Palmitic [c] Linoleate [d] Linolenic
[a]
[ "[b]", "[c]", "[d]" ]
[ "[b] Palmitic", "[c] Linoleate", "[d] Linolenic" ]
[c] Linoleate
Choose the correct answer from the options below.
[ { "content": "Which of these fatty acids is found exclusively in breast milk?\n\n[a] Docosahexaenoic acid\n[b] Palmitic\n[c] Linoleate\n[d] Linolenic", "role": "user" }, { "content": "[a] Docosahexaenoic acid", "role": "assistant" } ]